iPTMnet Report for O15552 (FFAR2)
Protein Information
UniProt AC / UniProt ID | O15552 / FFAR2_HUMAN |
Protein Name | Free fatty acid receptor 2 |
Gene Name | Name: FFAR2 Synonyms:FFA2,GPCR43,GPR43; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O15552 |
PRO Name | free fatty acid receptor 2 (human) |
Definition | A free fatty acid receptor 2 that is encoded in the genome of human. |
Short Label | hFFAR2 |
Category | organism-gene |
O15552 (FFAR2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R255 | Methylation | score1 | PhosphoSitePlus | |||
S256 | Phosphorylation | score1 | PhosphoSitePlus | |||
R281 | Methylation | score1 | PhosphoSitePlus | |||
R286 | Methylation | score1 | PhosphoSitePlus | |||
S296 | Phosphorylation | score1 | PhosphoSitePlus | |||
S297 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R255 | L255 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R255 | W255 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] | |
R281 | C281 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
S296 | F296 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S297 | F297 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |