PR:000045470	presenilin-1 sequence variant E280K (human)	hPSEN1/var:E280K|UniProtKB:P49768-1, Glu-280, CHEBI:29967		associated_with_disease_progression	DOID:10652	Alzheimer's disease			Alzforum:psen1-e280k	EXP	NCBITaxon:9606		Alzforum:psen1-e280k	20180510	PRO:DAN