PR:000037687	presenilin-1 sequence variant R278I (human)	hPSEN1/var:R278I|UniProtKB:P49768-1, Arg-278, CHEBI:30009		associated_with_disease_progression	DOID:10652	Alzheimer's disease			Alzforum:psen1-r278i	EXP	NCBITaxon:9606		Alzforum:psen1-r278i	20180510	PRO:DAN