[Term]
id: PR:000050310
name: IgG2 immunoglobulin complex, circulating (human)
def: "An IgG2 immunoglobulin complex (human) that is composed of two identical immunoglobulin heavy chains of an IgG2 isotype of the secretory isoform and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, PMID:25368619, PRO:ADD]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL.
synonym: "hIgG2/circulating" EXACT PRO-short-label [PRO:ADD, GOC:add]
synonym: "IgG antibody (human)" BROAD [PRO:ADD, GOC:add]
synonym: "IgG2 antibody (human)" EXACT [PRO:ADD, GOC:add]
is_a: PR:000050306 ! IgG2 immunoglobulin complex (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000050183 {cardinality="2"} ! immunoglobulin light chain protein (human)
relationship: has_component PR:000050298 {cardinality="2"} ! IgG2 heavy chain protein, secretory isoform (human)