[Term]
id: PR:000050159
name: IgA1 immunoglobulin complex, circulating (human)
def: "An IgA immunoglobulin complex, circulating that in monomeric form is composed of two identical immunoglobulin heavy chains of the secretory isoform of the IgA1 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
comment: Category=organism-complex. Requested by=HIPC. Requested by=CL.
synonym: "hIgA1/circulating" EXACT PRO-short-label [PRO:DAN]
synonym: "IgA antibody (human)" BROAD [PRO:ADD, GOC:add]
synonym: "IgA1 antibody (human)" EXACT [PRO:ADD, GOC:add]
is_a: GO:0071746 ! IgA immunoglobulin complex, circulating
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000050183 ! immunoglobulin light chain protein (human)
relationship: has_component PR:000050376 ! IgA1 heavy chain protein, secretory isoform (human)