[Term]
id: PR:000044662
name: acid-sensing ion channel protein
def: "A ligand-gated ion channel protein that has acid-sensing ion channel activity. An acid-sensing (aka proton-gated) ion channel opens when an extracellular proton has been bound by the channel complex, and enables the transmembrane transfer of a sodium ion." [GO:0044736, PRO:DAN, PRO:XQ]
comment: Category=family. Note: Acid-sensing ion channels operate as homo- or heterotrimers. [PRO:DAN, IUPHARfam:118]
synonym: "ASIC protein" EXACT [PRO:XQ]
synonym: "fam:ASIC_chan" EXACT PRO-short-label [PRO:DAN]
synonym: "proton-gated ion channel protein" EXACT [PRO:DAN]
xref: IUPHARfam:118
intersection_of: capable_of GO:0044736 ! acid-sensing ion channel activity
intersection_of: PR:000044671 ! ligand-gated ion channel protein