[Term]
id: PR:000037474
name: activated TLR4 complex (chicken)
def: "An activated TLR4 complex whose components are encoded in the genome of chicken. LPS binding to Toll-like receptor 4 results in dimerization of the TLR4 associated with MD2." [PMID:18768894, PMID:24034933, Reactome:R-GGA-433789]
comment: Category=organism-complex. Requested by=TLR.
synonym: "chick-TLR4actv" EXACT PRO-short-label [PRO:DAN]
synonym: "chick-(LY96:LPS:TLR4)" EXACT [PRO:DAN]
synonym: "MD2:LPS:TLR4 (chicken)" EXACT []
synonym: "LY96:LPS:TLR4 complex (chicken)" EXACT []
xref: Reactome:R-GGA-433789 "PR:000037474 located_in GO:0005886"
is_a: PR:000036076 ! activated TLR4 complex
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus
relationship: has_component PR:A0A1D5NZX9 {cardinality="2"} ! lymphocyte antigen 96 (chicken)
relationship: has_component PR:Q7ZTG5 {cardinality="2"} ! Toll-like receptor 4 (chicken)