[Term]
id: PR:000037309
name: traf3:ticam1:activated TLR3 complex
def: "A protein-containing complex that is composed of activated Toll-like receptor 3, TICAM1 (TRIF) and TRAF3." [PMID:16306937]
comment: Category=complex. Requested by=TLR.
synonym: "TLR3TLR3dsRNATriftraf3" EXACT []
synonym: "TRAF3:TRIF:activated TLR3" EXACT [Reactome:R-HSA-2201339]
is_a: GO:0032991 ! protein-containing complex

[Term]
id: PR:000037310
name: traf3:ticam1:activated TLR3 complex (human)
def: "A traf3:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PRO:VS, Reactome:R-HSA-2201339]
comment: Category=organism-complex. Requested by=TLR.
synonym: "TRAF3:TRIF:activated TLR3 (human)" EXACT [Reactome:R-HSA-2201339]
is_a: PR:000037309 ! traf3:ticam1:activated TLR3 complex
relationship: has_component CHEBI:67208 {cardinality="1"} ! dsRNA
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000037305 {cardinality="2"} ! Toll-like receptor 3, signal peptide removed form (human)
relationship: has_component PR:Q13114 {cardinality="2"} ! TNF receptor-associated factor 3 (human)
relationship: has_component PR:Q8IUC6 {cardinality="2"} ! TIR domain-containing adapter molecule 1 (human)

[Term]
id: PR:000037311
name: traf3:ticam1:activated TLR3 complex (mouse)
def: "A traf3:ticam1:activated TLR3 complex whose components are encoded in the genome of mouse." [PMID:16306936, PMID:16306937, TLR:AMM]
comment: Category=organism-complex. Requested by=TLR.
synonym: "TLR3TLR3dsRNATriftraf3 (mouse)" EXACT []
synonym: "TRAF3:TRIF:activated TLR3 (mouse)" EXACT []
is_a: PR:000037309 ! traf3:ticam1:activated TLR3 complex
relationship: has_component CHEBI:67208 {cardinality="1"} ! dsRNA
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_component PR:000037789 {cardinality="2"} ! Toll-like receptor 3, signal peptide removed form (mouse)
relationship: has_component PR:Q60803 {cardinality="2"} ! TNF receptor-associated factor 3 (mouse)
relationship: has_component PR:Q80UF7 {cardinality="2"} ! TIR domain-containing adapter molecule 1 (mouse)