[Term]
id: PR:000036824
name: NS1
def: "A dengue virus genome polyprotein proteolytic cleavage product that is the N-terminal most non-structural protein within the dengue virus genome polyprotein. Example: UniProtKB:P29990, 776-1127, Asn-905/Asn-982, MOD:00160." [PRO:ES]
comment: Category=modification. Requested by=IDODEN. NS1 is a secreted glycoprotein that is absent from viral particles but accumulates in the supernatant and on the plasma membrane of cells during infection. Because it derives from a glycosylated precursor it includes two N-glycosylated residues at Asn-130 and Asn-207. [PMID:18052531, PRO:ES].
synonym: "DenV-NS1" EXACT PRO-short-label [PRO:DAN]
synonym: "non-structural protein 1" EXACT []
intersection_of: has_part MOD:00160 ! N4-glycosyl-L-asparagine
intersection_of: PR:000036818 ! dengue virus genome polyprotein proteolytic cleavage product
intersection_of: lacks_part PR:000036825 ! NS2A
intersection_of: derives_from PR:000036998 ! NS1-NS2A