[Term] id: PR:P14337 name: genome polyprotein (Dengue virus 2 Thailand/0168/1979) def: "A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Thailand/0168/1979." [PRO:ES] comment: Category=organism-gene. synonym: "polyprot (DEN28)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P14337 intersection_of: only_in_taxon NCBITaxon:413041 ! Dengue virus 2 Thailand/0168/1979 intersection_of: PR:000036816 ! dengue virus genome polyprotein [Term] id: PR:000036816 name: dengue virus genome polyprotein def: "A protein that is a translation product of the dengue virus serotype 2 genomic RNA or a 1:1 ortholog thereof." [PRO:ES] comment: Category=gene. Requested by=IDODEN. The dengue virus contains a 10.7 kb single-stranded RNA genome of positive strand polarity with a type I cap at the 5' terminus. The RNA genome is translated into a large glycosylated polyprotein precursor with proteins that are arranged in the order NH2-C-prM-E-NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5-COOH. Proteolytic processing in the region of the structural proteins is mediated by a host cell signal peptidase that is located within the endoplasmic reticulum. [PMID:12297031, PRO:ES] synonym: "DenV-polyprot" EXACT PRO-short-label [PRO:DAN] is_a: PR:000000001 ! protein