[Term]
id: PR:000035435
name: mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human)
def: "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 in human. This phosphorylated form is observed in prophase, prometaphase, metaphase, anaphase, spindle depolymerization (nocodazole). This form is not observed when there is a lack of kinetochore tension (taxol). Ser-435, Ser-574 and Ser-720 could also be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER]
comment: Category=organism-modification. Kinase=("CDK1"; PR:000003271).
synonym: "hBUB1B/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "hBUBR1 phosphorylated" RELATED []
synonym: "BUBR1 phosphorylated (human)" RELATED []
synonym: "UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035434 ! mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4
relationship: has_part MOD:00046 ! O-phospho-L-serine