[Term] id: PR:000028988 name: sterol regulatory element-binding protein def: "A protein that is a transmembrane protein where the N- and C-termini are both cytosolic, and the N terminus contains a basic helix-loop-helix domain (Pfam:PF00010) and functions as a transcription factor when cleaved off." [PMID:17303406] comment: Category=family. synonym: "SRE" RELATED [] synonym: "SREBF" RELATED [] synonym: "SREBP" RELATED [] synonym: "bHLHd1" BROAD [PRO:DNx] synonym: "class D basic helix-loop-helix protein 1" BROAD [PRO:DNx] synonym: "sterol regulatory element-binding transcription factor" EXACT [] is_a: PR:000000001 ! protein