[Term] id: PR:000045300 name: histone H3.3, initiator methionine removed ADP-ribosylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-38 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-38, MOD:01399." [HIstome_var_Hs:Histone_H3.3, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K37ar" BROAD [HIstome_ptm_Hs:H3K37ar] synonym: "hH3.3/InitMet-/ADPrib:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-38, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045301 name: histone H3.3, initiator methionine removed trimethylated 4 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-37, MOD:00083." [HIstome_var_Hs:Histone_H3.3, PMID:19483677, PMID:20018718, PMID:21239496, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K36me3" BROAD [HIstome_ptm_Hs:H3K36me3] synonym: "hH3.3/InitMet-/Me3:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-37, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045302 name: histone H3.3, initiator methionine removed dimethylated 5 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-28, MOD:00084." [HIstome_var_Hs:Histone_H3.3, PMID:18172012, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K27me2" BROAD [HIstome_ptm_Hs:H3K27me2] synonym: "hH3.3/InitMet-/Me2:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-28, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:13022 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045303 name: histone H3.3, initiator methionine removed acetylated 7 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-57 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-57, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:19270680, PMID:19625767, PMID:20587414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K56ac" BROAD [HIstome_ptm_Hs:H3K56ac] synonym: "hH3.3/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-57, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045304 name: histone H3.3, initiator methionine removed citrullinated 4 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-3, MOD:00219." [HIstome_var_Hs:Histone_H3.3, PMID:15339660, PMID:17079667, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R2ci" BROAD [HIstome_ptm_Hs:H3R2ci] synonym: "hH3.3/InitMet-/Cit:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-3, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045305 name: histone H3.3, initiator methionine removed phosphorylated 7 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Ser-29, MOD:00046." [HIstome_var_Hs:Histone_H3.3, PMID:11856369, PMID:21282660, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3S28ph" BROAD [HIstome_ptm_Hs:H3S28ph] synonym: "hH3.3/InitMet-/Phos:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Ser-29, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:13207 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045269 name: histone H3.3, initiator methionine removed phosphorylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-12 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Thr-12, MOD:00047." [HIstome_var_Hs:Histone_H3.3, PMID:12560483, PMID:18066052, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3T11ph" BROAD [HIstome_ptm_Hs:H3T11ph] synonym: "hH3.3/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Thr-12, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5625878 "PR:000045269 located_in GO:0005654" is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045268 name: histone H3.2, initiator methionine removed dimethylated 8 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00084." [HIstome_var_Hs:Histone_H3.2, PMID:16861263, PMID:21187428, PMID:21239496, PMID:21310926, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K36me2" BROAD [HIstome_ptm_Hs:H3K36me2] synonym: "hH3.2/InitMet-/Me2:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4722126 "PR:000045268 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045267 name: histone H3.2, initiator methionine removed acetylated 8 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-15 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-15, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:12419248, PMID:16678094, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K14ac" BROAD [HIstome_ptm_Hs:H3K14ac] synonym: "hH3.2/InitMet-/Ac:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-15, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4549224 "PR:000045267 located_in GO:0005654" xref: Reactome:R-HSA-4568755 "PR:000045267 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045266 name: histone H3.2, initiator methionine removed monomethylated 8 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-18, MOD:00414." [HIstome_var_Hs:Histone_H3.2, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R17me1" BROAD [HIstome_ptm_Hs:H3R17me1] synonym: "hH3.2/InitMet-/Me1:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-18, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045265 name: histone H3.2, initiator methionine removed dimethylated 7 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-18, MOD:00783." [HIstome_var_Hs:Histone_H3.2, PMID:16705743, PMID:17478518, PMID:18172323, PMID:18172323, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R17me2" BROAD [HIstome_ptm_Hs:H3R17me2] synonym: "hH3.2/InitMet-/Me2:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-18, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045264 name: histone H3.2, initiator methionine removed trimethylated 5 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00083." [HIstome_var_Hs:Histone_H3.2, PMID:16061184, PMID:16861263, PMID:17403718, PMID:17478518, PMID:17968314, PMID:18579779, PMID:19593370, PMID:19739128, PMID:20404089, PMID:20498303, PMID:20843831, PMID:21062507, PMID:21430779, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K9me3" BROAD [HIstome_ptm_Hs:H3K9me3] synonym: "hH3.2/InitMet-/Me3:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-427744 "PR:000045264 located_in GO:0005654" xref: Reactome:R-HSA-4754191 "PR:000045264 located_in GO:0005654" xref: TDR:8242 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045263 name: histone H3.2, initiator methionine removed dimethylated 6 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00084." [HIstome_var_Hs:Histone_H3.2, PMID:12232854, PMID:15153943, PMID:16861263, PMID:17314394, PMID:17901401, PMID:18552846, PMID:18776137, PMID:18850007, PMID:19349354, PMID:19349354, PMID:19739128, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K9me2" BROAD [HIstome_ptm_Hs:H3K9me2] synonym: "hH3.2/InitMet-/Me2:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-427407 "PR:000045263 located_in GO:0005654" xref: Reactome:R-HSA-4724280 "PR:000045263 located_in GO:0005654" xref: TDR:12360 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045221 name: histone H3.1, initiator methionine removed acetylated 8 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-15 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-15, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:12419248, PMID:16678094, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K14ac" BROAD [HIstome_ptm_Hs:H3K14ac] synonym: "hH3.1/InitMet-/Ac:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-15, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4549217 "PR:000045221 located_in GO:0005654" xref: Reactome:R-HSA-4568743 "PR:000045221 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045261 name: histone H3.2, initiator methionine removed phosphorylated 7 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Tyr-42 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Tyr-42, MOD:00048." [HIstome_var_Hs:Histone_H3.2, PMID:19783980, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3Y41ph" BROAD [HIstome_ptm_Hs:H3Y41ph] synonym: "hH3.2/InitMet-/Phos:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Tyr-42, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045260 name: histone H3.2, initiator methionine removed phosphorylated 6 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Ser-29, MOD:00046." [HIstome_var_Hs:Histone_H3.2, PMID:11856369, PMID:21282660, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3S28ph" BROAD [HIstome_ptm_Hs:H3S28ph] synonym: "hH3.2/InitMet-/Phos:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Ser-29, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000036805 name: histone H3.2 acetylated and trimethylated 1 (human) def: "A histone H3.2 acetylated and methylated form in human that has been trimethylated at positions equivalent to Lys-10 and Lys-37, and acetylated at Lys-19, Lys-24 and Lys-28 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, Met-1, MOD:00058|Lys-10/Lys-37, MOD:00083|Lys-19/Lys-24/Lys-28, MOD:00064." [PRO:CNA, PRO:DAN, TDR:1743] comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006). synonym: "hH3.2(any)/AcMe3:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:Q71DI3, Met-1, MOD:00058|Lys-10/Lys-37, MOD:00083|Lys-19/Lys-24/Lys-28, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:1743 is_a: PR:000036795 ! histone H3.2 acetylated and methylated form relationship: has_part MOD:00058 ! N-acetyl-L-methionine relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045220 name: histone H3.1, initiator methionine removed monomethylated 8 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-18, MOD:00414." [HIstome_var_Hs:Histone_H3.1, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R17me1" BROAD [HIstome_ptm_Hs:H3R17me1] synonym: "hH3.1/InitMet-/Me1:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-18, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000036800 name: histone H3.3 acetylated and methylated 1 (human) def: "A histone H3.3 that has been acetylated on the N-terminal Met and methylated and acetylated on several Lys residues in human. UniProtKB:P84243, Met-1, MOD:00058|Lys-10, MOD:00083|Lys-28, MOD:00084|Lys-80, MOD:00064." [TDR:7224] comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006). synonym: "hH3.3/AcMe:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:P84243, Met-1, MOD:00058|Lys-10, MOD:00083|Lys-28, MOD:00084|Lys-80, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:7224 is_a: PR:000008425 ! histone H3.3 relationship: has_part MOD:00058 ! N-acetyl-L-methionine relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045179 name: histone H3.1, initiator methionine removed phosphorylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-12 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Thr-12, MOD:00047." [HIstome_var_Hs:Histone_H3.1, PMID:12560483, PMID:18066052, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3T11ph" BROAD [HIstome_ptm_Hs:H3T11ph] synonym: "hH3.1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Thr-12, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5625872 "PR:000045179 located_in GO:0005654" xref: TDR:13201 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045306 name: histone H3.3, initiator methionine removed phosphorylated 8 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Tyr-42 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Tyr-42, MOD:00048." [HIstome_var_Hs:Histone_H3.3, PMID:19783980, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3Y41ph" BROAD [HIstome_ptm_Hs:H3Y41ph] synonym: "hH3.3/InitMet-/Phos:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Tyr-42, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045307 name: histone H3.3, initiator methionine removed monomethylated 7 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00085." [HIstome_var_Hs:Histone_H3.3, PMID:16079795, PMID:16517599, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K9Me1" BROAD [HIstome_ptm_Hs:H3K9Me1] synonym: "hH3.3/InitMet-/Me1:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-427369 "PR:000045307 located_in GO:0005654" xref: TDR:14858 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045308 name: histone H3.3, initiator methionine removed dimethylated 6 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00084." [HIstome_var_Hs:Histone_H3.3, PMID:12232854, PMID:15153943, PMID:16861263, PMID:17314394, PMID:17901401, PMID:18552846, PMID:18776137, PMID:18850007, PMID:19349354, PMID:19349354, PMID:19739128, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K9me2" BROAD [HIstome_ptm_Hs:H3K9me2] synonym: "hH3.3/InitMet-/Me2:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-427324 "PR:000045308 located_in GO:0005654" xref: TDR:5808 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045309 name: histone H3.3, initiator methionine removed trimethylated 5 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00083." [HIstome_var_Hs:Histone_H3.3, PMID:16061184, PMID:16861263, PMID:17403718, PMID:17478518, PMID:17968314, PMID:18579779, PMID:19593370, PMID:19739128, PMID:20404089, PMID:20498303, PMID:20843831, PMID:21062507, PMID:21430779, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K9me3" BROAD [HIstome_ptm_Hs:H3K9me3] synonym: "hH3.3/InitMet-/Me3:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5625747 "PR:000045309 located_in GO:0005654" xref: TDR:12361 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047874 name: histone H3.1t, initiator methionine removed dimethylated 1 (human) def: "A histone H3.1t (human) that has had the initiator methionine removed and has been post-translationally modified to include dimethyl-L-lysine at position 5 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-5, MOD:00084." [PRO:DNx, Reactome:R-HSA-2245186] comment: Category=organism-modification. synonym: "hHIST3H3/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q16695, 2-136, Lys-5, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-2245186 "PR:000047874 located_in GO:0005654" is_a: PR:Q16695 ! histone H3.1t (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045229 name: histone H3.2, initiator methionine removed citrullinated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-27 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-27, MOD:00219." [HIstome_var_Hs:Histone_H3.2, PMID:15339660, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R26ci" BROAD [HIstome_ptm_Hs:H3R26ci] synonym: "hH3.2/InitMet-/Cit:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-27, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246539 "PR:000045229 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000047873 name: histone H3.1t, initiator methionine removed form (human) def: "A histone H3.1t (human) that has had the initiator methionine removed. UniProtKB:Q16695, 2-136." [PRO:DNx, Reactome:R-HSA-181914] comment: Category=organism-modification. synonym: "PRO_0000221248" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hHIST3H3/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q16695, 2-136" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-181914 "PR:000047873 located_in GO:0005654" xref: TDR:6109 intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:Q16695 ! histone H3.1t (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045313 name: histone H3.3, initiator methionine removed dimethylated 8 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-37, MOD:00084." [HIstome_var_Hs:Histone_H3.3, PMID:16861263, PMID:21187428, PMID:21239496, PMID:21310926, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K36me2" BROAD [HIstome_ptm_Hs:H3K36me2] synonym: "hH3.3/InitMet-/Me2:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-37, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045312 name: histone H3.3, initiator methionine removed acetylated 8 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-15 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-15, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:12419248, PMID:16678094, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K14ac" BROAD [HIstome_ptm_Hs:H3K14ac] synonym: "hH3.3/InitMet-/Ac:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-15, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045258 name: histone H3.2, initiator methionine removed acetylated 7 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-57 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-57, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:19270680, PMID:19625767, PMID:20587414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K56ac" BROAD [HIstome_ptm_Hs:H3K56ac] synonym: "hH3.2/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-57, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045228 name: histone H3.2, initiator methionine removed phosphorylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-4 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Thr-4, MOD:00047." [HIstome_var_Hs:Histone_H3.2, PMID:15681610, PMID:19622635, PMID:20705812, PMID:20929775, PMID:20953165, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3T3ph" BROAD [HIstome_ptm_Hs:H3T3ph] synonym: "hH3.2/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Thr-4, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:13158 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045314 name: histone H3.3C, initiator methionine removed phosphorylated 1 (human) def: "A histone H3.3C (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-32 of the amino acid sequence represented by UniProtKB:Q6NXT2. UniProtKB:Q6NXT2, 2-135, Ser-32, MOD:00046." [HIstome_var_Hs:Histone_H3.3C, PMID:15851689, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3C:H3S31ph" BROAD [HIstome_ptm_Hs:H3S31ph] synonym: "hH3F3C/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q6NXT2, 2-135, Ser-32, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q6NXT2 ! histone H3.3C (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045252 name: histone H3.2, initiator methionine removed acetylated 5 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:12419248, PMID:16544193, PMID:17403718, PMID:17478518, PMID:17906200, PMID:18337721, PMID:19135889, PMID:20816089, PMID:20972224, PMID:21453398, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K9ac" BROAD [HIstome_ptm_Hs:H3K9ac] synonym: "hH3.2/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045253 name: histone H3.2, initiator methionine removed acetylated 6 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-19, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:15988529, PMID:18552846, PMID:18953329, PMID:19349354, PMID:19349354, PMID:20841388, PMID:20978174, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K18ac" BROAD [HIstome_ptm_Hs:H3K18ac] synonym: "hH3.2/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-19, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568750 "PR:000045253 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045250 name: histone H3.2, initiator methionine removed dimethylated 4 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-80, MOD:00084." [HIstome_var_Hs:Histone_H3.2, PMID:12123582, PMID:16307923, PMID:20699226, PMID:21741597, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K79me2" BROAD [HIstome_ptm_Hs:H3K79me2] synonym: "hH3.2/InitMet-/Me2:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-80, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5649803 "PR:000045250 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045251 name: histone H3.2, initiator methionine removed trimethylated 3 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-80, MOD:00083." [HIstome_var_Hs:Histone_H3.2, PMID:12628190, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K79me3" BROAD [HIstome_ptm_Hs:H3K79me3] synonym: "hH3.2/InitMet-/Me3:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-80, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5649798 "PR:000045251 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045256 name: histone H3.2, initiator methionine removed trimethylated 4 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00083." [HIstome_var_Hs:Histone_H3.2, PMID:19483677, PMID:20018718, PMID:21239496, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K36me3" BROAD [HIstome_ptm_Hs:H3K36me3] synonym: "hH3.2/InitMet-/Me3:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5638140 "PR:000045256 located_in GO:0005654" xref: TDR:7093 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045257 name: histone H3.2, initiator methionine removed dimethylated 5 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00084." [HIstome_var_Hs:Histone_H3.2, PMID:18172012, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K27me2" BROAD [HIstome_ptm_Hs:H3K27me2] synonym: "hH3.2/InitMet-/Me2:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4754197 "PR:000045257 located_in GO:0005654" xref: TDR:7507 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045254 name: histone H3.2, initiator methionine removed citrullinated 3 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-18, MOD:00219." [HIstome_var_Hs:Histone_H3.2, PMID:15339660, PMID:15345777, PMID:17079667, PMID:18209087, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R17ci" BROAD [HIstome_ptm_Hs:H3R17ci] synonym: "hH3.2/InitMet-/Cit:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-18, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246536 "PR:000045254 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045255 name: histone H3.2, initiator methionine removed ADP-ribosylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-38 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-38, MOD:01399." [HIstome_var_Hs:Histone_H3.2, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K37ar" BROAD [HIstome_ptm_Hs:H3K37ar] synonym: "hH3.2/InitMet-/ADPrib:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-38, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045310 name: histone H3.3, initiator methionine removed dimethylated 7 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-18, MOD:00783." [HIstome_var_Hs:Histone_H3.3, PMID:16705743, PMID:17478518, PMID:18172323, PMID:18172323, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R17me2" BROAD [HIstome_ptm_Hs:H3R17me2] synonym: "hH3.3/InitMet-/Me2:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-18, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:Q16695 name: histone H3.1t (human) def: "A histone H3.1t that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16695] comment: Category=organism-gene. synonym: "H3-4" RELATED Gene-based [UniProtKB:Q16695] synonym: "H3FT" RELATED Gene-based [UniProtKB:Q16695] synonym: "hH3-4" EXACT PRO-short-label [PRO:DNx] synonym: "HIST3H3" RELATED Gene-based [UniProtKB:Q16695] synonym: "H3t (human)" EXACT [UniProtKB:Q16695] synonym: "H3/g (human)" EXACT [UniProtKB:Q16695] synonym: "H3/t (human)" EXACT [UniProtKB:Q16695] synonym: "histone H3.4 (human)" EXACT [UniProtKB:Q16695] xref: UniProtKB:Q16695 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008602 ! histone H3.1t relationship: has_gene_template HGNC:4778 ! H3-4 (human) [Term] id: PR:000036265 name: histone H3.2 acetylated 1 (human) def: "A histone H3.2 (human) that has been N-terminal Met acetylated. UniProtKB:Q71DI3, Met-1, MOD:00058." [PRO:CNA, PRO:DAN, TDR:1530] comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006). synonym: "hH3.2/Ac:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:Q71DI3, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:1530 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00058 ! N-acetyl-L-methionine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000036264 name: histone H3.1 acetylated 1 (human) def: "A histone H3.1 (human) that has been N-terminal Met acetylated. UniProtKB:P68431, Met-1, MOD:00058." [PRO:CNA, PRO:DAN, TDR:1490] comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006). synonym: "hH3.1/Ac:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:P68431, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:1490 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00058 ! N-acetyl-L-methionine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045213 name: histone H3.1, initiator methionine removed citrullinated 4 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-3, MOD:00219." [HIstome_var_Hs:Histone_H3.1, PMID:15339660, PMID:17079667, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R2ci" BROAD [HIstome_ptm_Hs:H3R2ci] synonym: "hH3.1/InitMet-/Cit:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-3, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246544 "PR:000045213 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045245 name: histone H3.2, initiator methionine removed phosphorylated 5 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-46 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Thr-46, MOD:00047." [HIstome_var_Hs:Histone_H3.2, PMID:19363025, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3T45ph" BROAD [HIstome_ptm_Hs:H3T45ph] synonym: "hH3.2/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Thr-46, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045244 name: histone H3.2, initiator methionine removed acetylated 3 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:18552846, PMID:20385584, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K27ac" BROAD [HIstome_ptm_Hs:H3K27ac] synonym: "hH3.2/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045247 name: histone H3.2, initiator methionine removed acetylated 4 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K4ac" BROAD [HIstome_ptm_Hs:H3K4ac] synonym: "hH3.2/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568752 "PR:000045247 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045246 name: histone H3.2, initiator methionine removed trimethylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00083." [HIstome_var_Hs:Histone_H3.2, PMID:12351676, PMID:12649488, PMID:16630819, PMID:17200670, PMID:17314394, PMID:18318442, PMID:18628788, PMID:18632628, PMID:18716661, PMID:19340297, PMID:19557159, PMID:19887624, PMID:21115743, PMID:21228036, PMID:21242977, PMID:21512140, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K27me3" BROAD [HIstome_ptm_Hs:H3K27me3] synonym: "hH3.2/InitMet-/Me3:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-212253 "PR:000045246 located_in GO:0005654" xref: Reactome:R-HSA-4754178 "PR:000045246 located_in GO:0005654" xref: TDR:13118 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045241 name: histone H3.2, initiator methionine removed dimethylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-3, MOD:00783." [HIstome_var_Hs:Histone_H3.2, PMID:17898714, PMID:18079182, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R2me2" BROAD [HIstome_ptm_Hs:H3R2me2] synonym: "hH3.2/InitMet-/Me2:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-3, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045240 name: histone H3.2, initiator methionine removed monomethylated 4 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-3, MOD:00414." [HIstome_var_Hs:Histone_H3.2, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R2me1" BROAD [HIstome_ptm_Hs:H3R2me1] synonym: "hH3.2/InitMet-/Me1:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-3, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045243 name: histone H3.2, initiator methionine removed biotinylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-19, MOD:00126." [HIstome_var_Hs:Histone_H3.2, PMID:20688500, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K18bio" BROAD [HIstome_ptm_Hs:H3K18bio] synonym: "hH3.2/InitMet-/Btn:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-19, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045242 name: histone H3.2, initiator methionine removed dimethylated 3 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-9, MOD:00783." [HIstome_var_Hs:Histone_H3.2, PMID:19998411, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R8me2" BROAD [HIstome_ptm_Hs:H3R8me2] synonym: "hH3.2/InitMet-/Me2:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-9, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045249 name: histone H3.2, initiator methionine removed monomethylated 6 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-80, MOD:00085." [HIstome_var_Hs:Histone_H3.2, PMID:20699226, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K79me1" BROAD [HIstome_ptm_Hs:H3K79me1] synonym: "hH3.2/InitMet-/Me1:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-80, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5649805 "PR:000045249 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045248 name: histone H3.2, initiator methionine removed monomethylated 5 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00085." [HIstome_var_Hs:Histone_H3.2, PMID:17030614, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K27me1" BROAD [HIstome_ptm_Hs:H3K27me1] synonym: "hH3.2/InitMet-/Me1:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-28, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5638326 "PR:000045248 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P84243 name: histone H3.3 (human) def: "A histone H3.3 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-gene. Note: The H3F3A and H3F3B genes encode identical proteins. synonym: "H3F3" RELATED Gene-based [UniProtKB:P84243] synonym: "H3-3A" RELATED Gene-based [UniProtKB:P84243] synonym: "H3-3B" RELATED Gene-based [UniProtKB:P84243] synonym: "H3.3A" NARROW Gene-based [PRO:DAN, UniProtKB:P84243] synonym: "H3.3B" NARROW Gene-based [PRO:DAN, UniProtKB:P84243] synonym: "H3F3A" NARROW Gene-based [PRO:DAN, UniProtKB:P84243] synonym: "H3F3B" NARROW Gene-based [PRO:DAN, UniProtKB:P84243] synonym: "PP781" RELATED Gene-based [UniProtKB:P84243] synonym: "hH3.3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P84243 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000008425 ! histone H3.3 relationship: has_gene_template HGNC:4764 ! H3F3A (human) relationship: has_gene_template HGNC:4765 ! H3F3B (human) [Term] id: PR:000036266 name: histone H3.3 acetylated 1 (human) def: "A histone H3.3 that is N-terminal Met acetylated in human. UniProtKB:P84243, Met-1, MOD:00058." [TDR:2154] comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006). synonym: "hH3.3/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:2154 xref: TDR:16791 is_a: PR:000008425 ! histone H3.3 relationship: has_part MOD:00058 ! N-acetyl-L-methionine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045230 name: histone H3.2, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-28, MOD:01399." [HIstome_var_Hs:Histone_H3.2, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K27ar" BROAD [HIstome_ptm_Hs:H3K27ar] synonym: "hH3.2/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-28, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045231 name: histone H3.2, initiator methionine removed trimethylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00083." [HIstome_var_Hs:Histone_H3.2, PMID:12453418, PMID:16307923, PMID:16510874, PMID:16630819, PMID:16731913, PMID:17478518, PMID:18033247, PMID:18850007, PMID:20035052, PMID:21060806, PMID:21922516, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K4me3" BROAD [HIstome_ptm_Hs:H3K4me3] synonym: "hH3.2/InitMet-/Me3:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1214223 "PR:000045231 located_in GO:0005654" xref: TDR:12951 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045232 name: histone H3.2, initiator methionine removed dimethylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00084." [HIstome_var_Hs:Histone_H3.2, PMID:11498594, PMID:12232854, PMID:12453418, PMID:15123803, PMID:15988529, PMID:17906200, PMID:18632628, PMID:19349354, PMID:19349354, PMID:20841388, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K4me2" BROAD [HIstome_ptm_Hs:H3K4me2] synonym: "hH3.2/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1214225 "PR:000045232 located_in GO:0005654" xref: TDR:13745 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045233 name: histone H3.2, initiator methionine removed monomethylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00085." [HIstome_var_Hs:Histone_H3.2, PMID:11498594, PMID:12453418, PMID:15123803, PMID:18809715, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K4me1" BROAD [HIstome_ptm_Hs:H3K4me1] synonym: "hH3.2/InitMet-/Me1:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-5, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4687009 "PR:000045233 located_in GO:0005654" xref: TDR:12313 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045234 name: histone H3.2, initiator methionine removed acetylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-24 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-24, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:21164480, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K23ac" BROAD [HIstome_ptm_Hs:H3K23ac] synonym: "hH3.2/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-24, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568747 "PR:000045234 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045235 name: histone H3.2, initiator methionine removed biotinylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00126." [HIstome_var_Hs:Histone_H3.2, PMID:20688500, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K9bio" BROAD [HIstome_ptm_Hs:H3K9bio] synonym: "hH3.2/InitMet-/Btn:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045236 name: histone H3.2, initiator methionine removed acetylated 2 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00064." [HIstome_var_Hs:Histone_H3.2, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K36ac" BROAD [HIstome_ptm_Hs:H3K36ac] synonym: "hH3.2/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045237 name: histone H3.2, initiator methionine removed monomethylated 3 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-27 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-27, MOD:00414." [HIstome_var_Hs:Histone_H3.2, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R26me1" BROAD [HIstome_ptm_Hs:H3R26me1] synonym: "hH3.2/InitMet-/Me1:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-27, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045238 name: histone H3.2, initiator methionine removed phosphorylated 3 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-7 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Thr-7, MOD:00047." [HIstome_var_Hs:Histone_H3.2, PMID:20228790, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3T6ph" BROAD [HIstome_ptm_Hs:H3T6ph] synonym: "hH3.2/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Thr-7, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045239 name: histone H3.2, initiator methionine removed phosphorylated 4 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-11 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Ser-11, MOD:00046." [HIstome_var_Hs:Histone_H3.2, PMID:10436156, PMID:12677454, PMID:14583461, PMID:16651411, PMID:18256527, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3S10ph" BROAD [HIstome_ptm_Hs:H3S10ph] synonym: "hH3.2/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Ser-11, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P68431 name: histone H3.1 (human) def: "A histone H3 that is a translation product of any of the following genes in human: HIST1H3A/HIST1H3B/HIST1H3C/HIST1H3D/HIST1H3E/HIST1H3F/HIST1H3G/HIST1H3H/HIST1H3I/HIST1H3J." [PRO:DNx, UniProtKB:P68431] comment: Category=organism-gene. Note: The HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, and HIST1H3J genes encode identical proteins. synonym: "H3C1" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C2" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C3" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C4" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C6" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C7" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C8" RELATED Gene-based [UniProtKB:P68431] synonym: "H3FA" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FB" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FC" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FD" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FF" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FH" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FI" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FJ" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FK" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FL" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3C10" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C11" RELATED Gene-based [UniProtKB:P68431] synonym: "H3C12" RELATED Gene-based [UniProtKB:P68431] synonym: "hH3.1" EXACT PRO-short-label [PRO:DNx] synonym: "HIST1H3A" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3B" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3C" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3D" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3E" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3F" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3G" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3H" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3I" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "HIST1H3J" NARROW Gene-based [PRO:DAN, UniProtKB:P68431] synonym: "H3FC HIST1H3C" RELATED Gene-based [UniProtKB:P68431] synonym: "histone H3/a (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/b (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/c (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/d (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/f (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/h (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/i (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/j (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/k (human)" NARROW [PRO:DAN, UniProtKB:P68431] synonym: "histone H3/l (human)" NARROW [PRO:DAN, UniProtKB:P68431] xref: UniProtKB:P68431 is_a: PR:000027594 ! histone H3 relationship: has_gene_template HGNC:4766 ! HIST1H3A (human) relationship: has_gene_template HGNC:4767 ! HIST1H3D (human) relationship: has_gene_template HGNC:4768 ! HIST1H3C (human) relationship: has_gene_template HGNC:4769 ! HIST1H3E (human) relationship: has_gene_template HGNC:4771 ! HIST1H3I (human) relationship: has_gene_template HGNC:4772 ! HIST1H3G (human) relationship: has_gene_template HGNC:4773 ! HIST1H3F (human) relationship: has_gene_template HGNC:4774 ! HIST1H3J (human) relationship: has_gene_template HGNC:4775 ! HIST1H3H (human) relationship: has_gene_template HGNC:4776 ! HIST1H3B (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045223 name: histone H3.1t, initiator methionine removed acetylated 1 (human) def: "A histone H3.1t (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-10, MOD:00064." [HIstome_var_Hs:Histone_H3.1t, PMID:12419248, PMID:16544193, PMID:17403718, PMID:17478518, PMID:17906200, PMID:18337721, PMID:19135889, PMID:20816089, PMID:20972224, PMID:21453398, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1t:H3K9ac" BROAD [HIstome_ptm_Hs:H3K9ac] synonym: "hHIST3H3/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q16695, 2-136, Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q16695 ! histone H3.1t (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045222 name: histone H3.1, initiator methionine removed dimethylated 8 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-37, MOD:00084." [HIstome_var_Hs:Histone_H3.1, PMID:16861263, PMID:21187428, PMID:21239496, PMID:21310926, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K36me2" BROAD [HIstome_ptm_Hs:H3K36me2] synonym: "hH3.1/InitMet-/Me2:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-37, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4722125 "PR:000045222 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045188 name: histone H3.1, initiator methionine removed acetylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-24 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-24, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:21164480, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K23ac" BROAD [HIstome_ptm_Hs:H3K23ac] synonym: "hH3.1/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-24, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568754 "PR:000045188 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045189 name: histone H3.1, initiator methionine removed biotinylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-10, MOD:00126." [HIstome_var_Hs:Histone_H3.1, PMID:20688500, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K9bio" BROAD [HIstome_ptm_Hs:H3K9bio] synonym: "hH3.1/InitMet-/Btn:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-10, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045227 name: histone H3.2, initiator methionine removed monomethylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00085." [HIstome_var_Hs:Histone_H3.2, PMID:17544230, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K36me1" BROAD [HIstome_ptm_Hs:H3K36me1] synonym: "hH3.2/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-37, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4722131 "PR:000045227 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045226 name: histone H3.2, initiator methionine removed citrullinated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-9, MOD:00219." [HIstome_var_Hs:Histone_H3.2, PMID:15339660, PMID:15345777, PMID:17079667, PMID:18209087, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R8ci" BROAD [HIstome_ptm_Hs:H3R8ci] synonym: "hH3.2/InitMet-/Cit:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-9, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246545 "PR:000045226 located_in GO:0005654" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045225 name: histone H3.2, initiator methionine removed phosphorylated 1 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-12 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Thr-12, MOD:00047." [HIstome_var_Hs:Histone_H3.2, PMID:12560483, PMID:18066052, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3T11ph" BROAD [HIstome_ptm_Hs:H3T11ph] synonym: "hH3.2/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Thr-12, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5625871 "PR:000045225 located_in GO:0005654" xref: TDR:13205 is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045224 name: histone H3.1t, initiator methionine removed acetylated 2 (human) def: "A histone H3.1t (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-15 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-15, MOD:00064." [HIstome_var_Hs:Histone_H3.1t, PMID:12419248, PMID:16678094, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1t:H3K14ac" BROAD [HIstome_ptm_Hs:H3K14ac] synonym: "hHIST3H3/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q16695, 2-136, Lys-15, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q16695 ! histone H3.1t (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045182 name: histone H3.1, initiator methionine removed phosphorylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-4 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Thr-4, MOD:00047." [HIstome_var_Hs:Histone_H3.1, PMID:15681610, PMID:19622635, PMID:20705812, PMID:20929775, PMID:20953165, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3T3ph" BROAD [HIstome_ptm_Hs:H3T3ph] synonym: "hH3.1/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Thr-4, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045183 name: histone H3.1, initiator methionine removed citrullinated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-27 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-27, MOD:00219." [HIstome_var_Hs:Histone_H3.1, PMID:15339660, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R26ci" BROAD [HIstome_ptm_Hs:H3R26ci] synonym: "hH3.1/InitMet-/Cit:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-27, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246532 "PR:000045183 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045180 name: histone H3.1, initiator methionine removed citrullinated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-9, MOD:00219." [HIstome_var_Hs:Histone_H3.1, PMID:15339660, PMID:15345777, PMID:17079667, PMID:18209087, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R8ci" BROAD [HIstome_ptm_Hs:H3R8ci] synonym: "hH3.1/InitMet-/Cit:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-9, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246530 "PR:000045180 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045181 name: histone H3.1, initiator methionine removed monomethylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-37, MOD:00085." [HIstome_var_Hs:Histone_H3.1, PMID:17544230, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K36me1" BROAD [HIstome_ptm_Hs:H3K36me1] synonym: "hH3.1/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-37, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4722135 "PR:000045181 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045186 name: histone H3.1, initiator methionine removed dimethylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-5, MOD:00084." [HIstome_var_Hs:Histone_H3.1, PMID:11498594, PMID:12232854, PMID:12453418, PMID:15123803, PMID:15988529, PMID:17906200, PMID:18632628, PMID:19349354, PMID:19349354, PMID:20841388, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K4me2" BROAD [HIstome_ptm_Hs:H3K4me2] synonym: "hH3.1/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-5, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1214170 "PR:000045186 located_in GO:0005654" xref: TDR:14007 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045187 name: histone H3.1, initiator methionine removed monomethylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-5, MOD:00085." [HIstome_var_Hs:Histone_H3.1, PMID:11498594, PMID:12453418, PMID:15123803, PMID:18809715, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K4me1" BROAD [HIstome_ptm_Hs:H3K4me1] synonym: "hH3.1/InitMet-/Me1:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-5, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4687016 "PR:000045187 located_in GO:0005654" xref: TDR:7683 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045184 name: histone H3.1, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-28, MOD:01399." [HIstome_var_Hs:Histone_H3.1, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K27ar" BROAD [HIstome_ptm_Hs:H3K27ar] synonym: "hH3.1/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-28, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045185 name: histone H3.1, initiator methionine removed trimethylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-5, MOD:00083." [HIstome_var_Hs:Histone_H3.1, PMID:12453418, PMID:16307923, PMID:16510874, PMID:16630819, PMID:16731913, PMID:17478518, PMID:18033247, PMID:18850007, PMID:20035052, PMID:21060806, PMID:21922516, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K4me3" BROAD [HIstome_ptm_Hs:H3K4me3] synonym: "hH3.1/InitMet-/Me3:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-5, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1214186 "PR:000045185 located_in GO:0005654" xref: TDR:12958 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P84243-1 name: histone H3.3 isoform 1 (human) def: "A histone H3.3 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hH3.3/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P84243-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040180 ! histone H3.3 isoform 1 [Term] id: PR:000035690 name: histone H3, initiator methionine removed unphosphorylated form (human) def: "A histone H3, initiator methionine removed unphosphorylated form in human." [PMID:21658950] comment: Category=organism-modification. synonym: "hH3(any)/InitMet-/PhosRes-" EXACT PRO-short-label [PRO:DAN] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035689 ! histone H3, initiator methionine removed unphosphorylated form [Term] id: PR:000035525 name: histone H3, initiator methionine removed phosphorylated 1 (human) def: "A histone H3, initiator methionine removed phosphorylated 1 in human. Phosphorylated on the Thr residue within the N-terminal sequence ARTKQ." [PMID:21658950] comment: Category=organism-modification. synonym: "hH3T3ph" EXACT [] synonym: "human histone H3 Thr-3" EXACT [] synonym: "hH3(any)/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DAN] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035524 ! histone H3, initiator methionine removed phosphorylated 1 [Term] id: PR:000045195 name: histone H3.1, initiator methionine removed dimethylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-3, MOD:00783." [HIstome_var_Hs:Histone_H3.1, PMID:17898714, PMID:18079182, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R2me2" BROAD [HIstome_ptm_Hs:H3R2me2] synonym: "hH3.1/InitMet-/Me2:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-3, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045194 name: histone H3.1, initiator methionine removed monomethylated 4 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-3, MOD:00414." [HIstome_var_Hs:Histone_H3.1, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R2me1" BROAD [HIstome_ptm_Hs:H3R2me1] synonym: "hH3.1/InitMet-/Me1:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-3, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045197 name: histone H3.1, initiator methionine removed biotinylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-19, MOD:00126." [HIstome_var_Hs:Histone_H3.1, PMID:20688500, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K18bio" BROAD [HIstome_ptm_Hs:H3K18bio] synonym: "hH3.1/InitMet-/Btn:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-19, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045196 name: histone H3.1, initiator methionine removed dimethylated 3 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-9, MOD:00783." [HIstome_var_Hs:Histone_H3.1, PMID:19998411, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R8me2" BROAD [HIstome_ptm_Hs:H3R8me2] synonym: "hH3.1/InitMet-/Me2:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-9, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045191 name: histone H3.1, initiator methionine removed monomethylated 3 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-27 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-27, MOD:00414." [HIstome_var_Hs:Histone_H3.1, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R26me1" BROAD [HIstome_ptm_Hs:H3R26me1] synonym: "hH3.1/InitMet-/Me1:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-27, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045190 name: histone H3.1, initiator methionine removed acetylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-37, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K36ac" BROAD [HIstome_ptm_Hs:H3K36ac] synonym: "hH3.1/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-37, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045193 name: histone H3.1, initiator methionine removed phosphorylated 4 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-11 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Ser-11, MOD:00046." [HIstome_var_Hs:Histone_H3.1, PMID:10436156, PMID:12677454, PMID:14583461, PMID:16651411, PMID:18256527, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3S10ph" BROAD [HIstome_ptm_Hs:H3S10ph] synonym: "hH3.1/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Ser-11, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:14837 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045192 name: histone H3.1, initiator methionine removed phosphorylated 3 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-7 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Thr-7, MOD:00047." [HIstome_var_Hs:Histone_H3.1, PMID:20228790, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3T6ph" BROAD [HIstome_ptm_Hs:H3T6ph] synonym: "hH3.1/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Thr-7, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045199 name: histone H3.1, initiator methionine removed phosphorylated 5 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-46 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Thr-46, MOD:00047." [HIstome_var_Hs:Histone_H3.1, PMID:19363025, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3T45ph" BROAD [HIstome_ptm_Hs:H3T45ph] synonym: "hH3.1/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Thr-46, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045198 name: histone H3.1, initiator methionine removed acetylated 3 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-28, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:18552846, PMID:20385584, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K27ac" BROAD [HIstome_ptm_Hs:H3K27ac] synonym: "hH3.1/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-28, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045262 name: histone H3.2, initiator methionine removed monomethylated 7 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00085." [HIstome_var_Hs:Histone_H3.2, PMID:16079795, PMID:16517599, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3K9Me1" BROAD [HIstome_ptm_Hs:H3K9Me1] synonym: "hH3.2/InitMet-/Me1:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Lys-10, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-417240 "PR:000045262 located_in GO:0005654" xref: Reactome:R-HSA-4724283 "PR:000045262 located_in GO:0005654" xref: Reactome:R-HSA-8943828 "PR:000045262 located_in GO:0005829" is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045311 name: histone H3.3, initiator methionine removed monomethylated 8 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-18, MOD:00414." [HIstome_var_Hs:Histone_H3.3, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R17me1" BROAD [HIstome_ptm_Hs:H3R17me1] synonym: "hH3.3/InitMet-/Me1:8" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-18, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045259 name: histone H3.2, initiator methionine removed citrullinated 4 (human) def: "A histone H3.2 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:Q71DI3. UniProtKB:Q71DI3, 2-136, Arg-3, MOD:00219." [HIstome_var_Hs:Histone_H3.2, PMID:15339660, PMID:17079667, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.2:H3R2ci" BROAD [HIstome_ptm_Hs:H3R2ci] synonym: "hH3.2/InitMet-/Cit:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q71DI3, 2-136, Arg-3, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:Q71DI3 ! histone H3.2 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:Q71DI3 name: histone H3.2 (human) def: "A histone H3.2 that is a translation product of any of the following genes in human: HIST2H3A/HIST2H3C/HIST2H3D." [PRO:DAN, UniProtKB:Q71DI3] comment: Category=organism-gene. Note: The HIST2H3A, HIST2H3C, and HIST2H3D genes encode identical proteins. synonym: "H3F2" NARROW Gene-based [PRO:DAN, UniProtKB:Q71DI3] synonym: "H3FM" NARROW Gene-based [PRO:DAN, UniProtKB:Q71DI3] synonym: "H3C13" RELATED Gene-based [UniProtKB:Q71DI3] synonym: "H3C14" RELATED Gene-based [UniProtKB:Q71DI3] synonym: "H3C15" RELATED Gene-based [UniProtKB:Q71DI3] synonym: "hH3.2" EXACT PRO-short-label [PRO:DNx] synonym: "HIST2H3A" NARROW Gene-based [PRO:DAN, UniProtKB:Q71DI3] synonym: "HIST2H3C" NARROW Gene-based [PRO:DAN, UniProtKB:Q71DI3] synonym: "HIST2H3D" NARROW Gene-based [PRO:DAN, UniProtKB:Q71DI3] synonym: "histone H3/m (human)" NARROW [PRO:DAN, UniProtKB:Q71DI3] synonym: "histone H3/o (human)" NARROW [PRO:DAN, UniProtKB:Q71DI3] synonym: "H3-clustered histone 13 (human)" EXACT [UniProtKB:Q71DI3] synonym: "H3-clustered histone 14 (human)" EXACT [UniProtKB:Q71DI3] synonym: "H3-clustered histone 15 (human)" EXACT [UniProtKB:Q71DI3] xref: UniProtKB:Q71DI3 is_a: PR:000036794 ! histone H3.2 relationship: has_gene_template HGNC:20503 ! HIST2H3C (human) relationship: has_gene_template HGNC:20505 ! HIST2H3A (human) relationship: has_gene_template HGNC:25311 ! HIST2H3D (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000045296 name: histone H3.3, initiator methionine removed trimethylated 3 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-80, MOD:00083." [HIstome_var_Hs:Histone_H3.3, PMID:12628190, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K79me3" BROAD [HIstome_ptm_Hs:H3K79me3] synonym: "hH3.3/InitMet-/Me3:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-80, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045297 name: histone H3.3, initiator methionine removed acetylated 5 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:12419248, PMID:16544193, PMID:17403718, PMID:17478518, PMID:17906200, PMID:18337721, PMID:19135889, PMID:20816089, PMID:20972224, PMID:21453398, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K9ac" BROAD [HIstome_ptm_Hs:H3K9ac] synonym: "hH3.3/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5250654 "PR:000045297 located_in GO:0005654" is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045294 name: histone H3.3, initiator methionine removed monomethylated 6 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-80, MOD:00085." [HIstome_var_Hs:Histone_H3.3, PMID:20699226, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K79me1" BROAD [HIstome_ptm_Hs:H3K79me1] synonym: "hH3.3/InitMet-/Me1:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-80, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045295 name: histone H3.3, initiator methionine removed dimethylated 4 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-80, MOD:00084." [HIstome_var_Hs:Histone_H3.3, PMID:12123582, PMID:16307923, PMID:20699226, PMID:21741597, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K79me2" BROAD [HIstome_ptm_Hs:H3K79me2] synonym: "hH3.3/InitMet-/Me2:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-80, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:12831 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045292 name: histone H3.3, initiator methionine removed acetylated 4 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-5, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K4ac" BROAD [HIstome_ptm_Hs:H3K4ac] synonym: "hH3.3/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-5, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045293 name: histone H3.3, initiator methionine removed monomethylated 5 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-28, MOD:00085." [HIstome_var_Hs:Histone_H3.3, PMID:17030614, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K27me1" BROAD [HIstome_ptm_Hs:H3K27me1] synonym: "hH3.3/InitMet-/Me1:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-28, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045290 name: histone H3.3, initiator methionine removed phosphorylated 6 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-46 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Thr-46, MOD:00047." [HIstome_var_Hs:Histone_H3.3, PMID:19363025, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3T45ph" BROAD [HIstome_ptm_Hs:H3T45ph] synonym: "hH3.3/InitMet-/Phos:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Thr-46, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045291 name: histone H3.3, initiator methionine removed trimethylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-28, MOD:00083." [HIstome_var_Hs:Histone_H3.3, PMID:12351676, PMID:12649488, PMID:16630819, PMID:17200670, PMID:17314394, PMID:18318442, PMID:18628788, PMID:18632628, PMID:18716661, PMID:19340297, PMID:19557159, PMID:19887624, PMID:21115743, PMID:21228036, PMID:21242977, PMID:21512140, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K27me3" BROAD [HIstome_ptm_Hs:H3K27me3] synonym: "hH3.3/InitMet-/Me3:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-28, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-212282 "PR:000045291 located_in GO:0005654" is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:Q6NXT2 name: histone H3.3C (human) def: "A histone H3.3C that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6NXT2] comment: Category=organism-gene. synonym: "H3-5" RELATED Gene-based [UniProtKB:Q6NXT2] synonym: "H3F3C" RELATED Gene-based [UniProtKB:Q6NXT2] synonym: "hH3-5" EXACT PRO-short-label [PRO:DNx] synonym: "histone H3.5 (human)" EXACT [UniProtKB:Q6NXT2] xref: UniProtKB:Q6NXT2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000029532 ! histone H3.3C relationship: has_gene_template HGNC:33164 ! H3-5 (human) [Term] id: PR:000045298 name: histone H3.3, initiator methionine removed acetylated 6 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-19, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:15988529, PMID:18552846, PMID:18953329, PMID:19349354, PMID:19349354, PMID:20841388, PMID:20978174, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K18ac" BROAD [HIstome_ptm_Hs:H3K18ac] synonym: "hH3.3/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-19, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045299 name: histone H3.3, initiator methionine removed citrullinated 3 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-18, MOD:00219." [HIstome_var_Hs:Histone_H3.3, PMID:15339660, PMID:15345777, PMID:17079667, PMID:18209087, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R17ci" BROAD [HIstome_ptm_Hs:H3R17ci] synonym: "hH3.3/InitMet-/Cit:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-18, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045218 name: histone H3.1, initiator methionine removed trimethylated 5 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-10, MOD:00083." [HIstome_var_Hs:Histone_H3.1, PMID:16061184, PMID:16861263, PMID:17403718, PMID:17478518, PMID:17968314, PMID:18579779, PMID:19593370, PMID:19739128, PMID:20404089, PMID:20498303, PMID:20843831, PMID:21062507, PMID:21430779, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K9me3" BROAD [HIstome_ptm_Hs:H3K9me3] synonym: "hH3.1/InitMet-/Me3:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-10, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-427734 "PR:000045218 located_in GO:0005654" xref: Reactome:R-HSA-4754188 "PR:000045218 located_in GO:0005654" xref: TDR:1538 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045219 name: histone H3.1, initiator methionine removed dimethylated 7 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-18, MOD:00783." [HIstome_var_Hs:Histone_H3.1, PMID:16705743, PMID:17478518, PMID:18172323, PMID:18172323, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R17me2" BROAD [HIstome_ptm_Hs:H3R17me2] synonym: "hH3.1/InitMet-/Me2:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-18, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045216 name: histone H3.1, initiator methionine removed monomethylated 7 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-10, MOD:00085." [HIstome_var_Hs:Histone_H3.1, PMID:16079795, PMID:16517599, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K9Me1" BROAD [HIstome_ptm_Hs:H3K9Me1] synonym: "hH3.1/InitMet-/Me1:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-10, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-212105 "PR:000045216 located_in GO:0005654" xref: Reactome:R-HSA-8943830 "PR:000045216 located_in GO:0005829" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045217 name: histone H3.1, initiator methionine removed dimethylated 6 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-10, MOD:00084." [HIstome_var_Hs:Histone_H3.1, PMID:12232854, PMID:15153943, PMID:16861263, PMID:17314394, PMID:17901401, PMID:18552846, PMID:18776137, PMID:18850007, PMID:19349354, PMID:19349354, PMID:19739128, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K9me2" BROAD [HIstome_ptm_Hs:H3K9me2] synonym: "hH3.1/InitMet-/Me2:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-10, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-427378 "PR:000045217 located_in GO:0005654" xref: TDR:8281 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045214 name: histone H3.1, initiator methionine removed phosphorylated 6 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Ser-29, MOD:00046." [HIstome_var_Hs:Histone_H3.1, PMID:11856369, PMID:21282660, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3S28ph" BROAD [HIstome_ptm_Hs:H3S28ph] synonym: "hH3.1/InitMet-/Phos:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Ser-29, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045215 name: histone H3.1, initiator methionine removed phosphorylated 7 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Tyr-42 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Tyr-42, MOD:00048." [HIstome_var_Hs:Histone_H3.1, PMID:19783980, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3Y41ph" BROAD [HIstome_ptm_Hs:H3Y41ph] synonym: "hH3.1/InitMet-/Phos:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Tyr-42, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045212 name: histone H3.1, initiator methionine removed acetylated 7 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-57 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-57, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:19270680, PMID:19625767, PMID:20587414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K56ac" BROAD [HIstome_ptm_Hs:H3K56ac] synonym: "hH3.1/InitMet-/Ac:7" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-57, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000027594 name: histone H3 def: "A core histone that is a translation product of one of the H3 gene variants. It is a core histone and contains a copy of the Histone (Pfam:PF00125) domain at its C-terminus." [PMID:18443735, PMID:19234519, PRO:CNA] comment: Category=family. synonym: "H3(any)" EXACT PRO-short-label [PRO:DAN] xref: PIRSF:PIRSF002051 is_a: PR:000043452 ! core histone [Term] id: PR:000045210 name: histone H3.1, initiator methionine removed trimethylated 4 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-37, MOD:00083." [HIstome_var_Hs:Histone_H3.1, PMID:19483677, PMID:20018718, PMID:21239496, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K36me3" BROAD [HIstome_ptm_Hs:H3K36me3] synonym: "hH3.1/InitMet-/Me3:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-37, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5638160 "PR:000045210 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045211 name: histone H3.1, initiator methionine removed dimethylated 5 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-28, MOD:00084." [HIstome_var_Hs:Histone_H3.1, PMID:18172012, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K27me2" BROAD [HIstome_ptm_Hs:H3K27me2] synonym: "hH3.1/InitMet-/Me2:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-28, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4754193 "PR:000045211 located_in GO:0005654" xref: TDR:12699 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045278 name: histone H3.3, initiator methionine removed acetylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-24 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-24, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:21164480, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K23ac" BROAD [HIstome_ptm_Hs:H3K23ac] synonym: "hH3.3/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-24, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045279 name: histone H3.3, initiator methionine removed biotinylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-10, MOD:00126." [HIstome_var_Hs:Histone_H3.3, PMID:20688500, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K9bio" BROAD [HIstome_ptm_Hs:H3K9bio] synonym: "hH3.3/InitMet-/Btn:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-10, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045274 name: histone H3.3, initiator methionine removed ADP-ribosylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-28, MOD:01399." [HIstome_var_Hs:Histone_H3.3, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K27ar" BROAD [HIstome_ptm_Hs:H3K27ar] synonym: "hH3.3/InitMet-/ADPrib:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-28, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045275 name: histone H3.3, initiator methionine removed trimethylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-5, MOD:00083." [HIstome_var_Hs:Histone_H3.3, PMID:12453418, PMID:16307923, PMID:16510874, PMID:16630819, PMID:16731913, PMID:17478518, PMID:18033247, PMID:18850007, PMID:20035052, PMID:21060806, PMID:21922516, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K4me3" BROAD [HIstome_ptm_Hs:H3K4me3] synonym: "hH3.3/InitMet-/Me3:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-5, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1214216 "PR:000045275 located_in GO:0005654" xref: TDR:12549 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045276 name: histone H3.3, initiator methionine removed dimethylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-5, MOD:00084." [HIstome_var_Hs:Histone_H3.3, PMID:11498594, PMID:12232854, PMID:12453418, PMID:15123803, PMID:15988529, PMID:17906200, PMID:18632628, PMID:19349354, PMID:19349354, PMID:20841388, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K4me2" BROAD [HIstome_ptm_Hs:H3K4me2] synonym: "hH3.3/InitMet-/Me2:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-5, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1214206 "PR:000045276 located_in GO:0005654" xref: TDR:13320 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045277 name: histone H3.3, initiator methionine removed monomethylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-5, MOD:00085." [HIstome_var_Hs:Histone_H3.3, PMID:11498594, PMID:12453418, PMID:15123803, PMID:18809715, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K4me1" BROAD [HIstome_ptm_Hs:H3K4me1] synonym: "hH3.3/InitMet-/Me1:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-5, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:2755 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045270 name: histone H3.3, initiator methionine removed citrullinated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-9, MOD:00219." [HIstome_var_Hs:Histone_H3.3, PMID:15339660, PMID:15345777, PMID:17079667, PMID:18209087, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R8ci" BROAD [HIstome_ptm_Hs:H3R8ci] synonym: "hH3.3/InitMet-/Cit:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-9, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045271 name: histone H3.3, initiator methionine removed monomethylated 1 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-37, MOD:00085." [HIstome_var_Hs:Histone_H3.3, PMID:17544230, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K36me1" BROAD [HIstome_ptm_Hs:H3K36me1] synonym: "hH3.3/InitMet-/Me1:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-37, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045272 name: histone H3.3, initiator methionine removed phosphorylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-4 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Thr-4, MOD:00047." [HIstome_var_Hs:Histone_H3.3, PMID:15681610, PMID:19622635, PMID:20705812, PMID:20929775, PMID:20953165, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3T3ph" BROAD [HIstome_ptm_Hs:H3T3ph] synonym: "hH3.3/InitMet-/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Thr-4, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:13799 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045273 name: histone H3.3, initiator methionine removed citrullinated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-27 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-27, MOD:00219." [HIstome_var_Hs:Histone_H3.3, PMID:15339660, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R26ci" BROAD [HIstome_ptm_Hs:H3R26ci] synonym: "hH3.3/InitMet-/Cit:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-27, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045281 name: histone H3.3, initiator methionine removed monomethylated 3 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-27 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-27, MOD:00414." [HIstome_var_Hs:Histone_H3.3, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R26me1" BROAD [HIstome_ptm_Hs:H3R26me1] synonym: "hH3.3/InitMet-/Me1:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-27, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045280 name: histone H3.3, initiator methionine removed acetylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-37 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-37, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K36ac" BROAD [HIstome_ptm_Hs:H3K36ac] synonym: "hH3.3/InitMet-/Ac:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-37, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045283 name: histone H3.3, initiator methionine removed phosphorylated 4 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-32 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Ser-32, MOD:00046." [HIstome_var_Hs:Histone_H3.3, PMID:15851689, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3S31ph" BROAD [HIstome_ptm_Hs:H3S31ph] synonym: "hH3.3/InitMet-/Phos:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Ser-32, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045282 name: histone H3.3, initiator methionine removed phosphorylated 3 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Thr-7 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Thr-7, MOD:00047." [HIstome_var_Hs:Histone_H3.3, PMID:20228790, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3T6ph" BROAD [HIstome_ptm_Hs:H3T6ph] synonym: "hH3.3/InitMet-/Phos:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Thr-7, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00047 ! O-phospho-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045285 name: histone H3.3, initiator methionine removed monomethylated 4 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-3, MOD:00414." [HIstome_var_Hs:Histone_H3.3, PMID:15186775, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R2me1" BROAD [HIstome_ptm_Hs:H3R2me1] synonym: "hH3.3/InitMet-/Me1:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-3, MOD:00414" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00414 ! monomethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045284 name: histone H3.3, initiator methionine removed phosphorylated 5 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been phosphorylated at the position equivalent to Ser-11 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Ser-11, MOD:00046." [HIstome_var_Hs:Histone_H3.3, PMID:10436156, PMID:12677454, PMID:14583461, PMID:16651411, PMID:18256527, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3S10ph" BROAD [HIstome_ptm_Hs:H3S10ph] synonym: "hH3.3/InitMet-/Phos:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Ser-11, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] xref: TDR:14482 is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045287 name: histone H3.3, initiator methionine removed dimethylated 3 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-9 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-9, MOD:00783." [HIstome_var_Hs:Histone_H3.3, PMID:19998411, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R8me2" BROAD [HIstome_ptm_Hs:H3R8me2] synonym: "hH3.3/InitMet-/Me2:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-9, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045286 name: histone H3.3, initiator methionine removed dimethylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Arg-3 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Arg-3, MOD:00783." [HIstome_var_Hs:Histone_H3.3, PMID:17898714, PMID:18079182, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3R2me2" BROAD [HIstome_ptm_Hs:H3R2me2] synonym: "hH3.3/InitMet-/Me2:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Arg-3, MOD:00783" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00783 ! dimethylated L-arginine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045289 name: histone H3.3, initiator methionine removed acetylated 3 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-28, MOD:00064." [HIstome_var_Hs:Histone_H3.3, PMID:18552846, PMID:20385584, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K27ac" BROAD [HIstome_ptm_Hs:H3K27ac] synonym: "hH3.3/InitMet-/Ac:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-28, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045288 name: histone H3.3, initiator methionine removed biotinylated 2 (human) def: "A histone H3.3 (human) that has had the initiator methionine removed and that has been biotinylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:P84243. UniProtKB:P84243, 2-136, Lys-19, MOD:00126." [HIstome_var_Hs:Histone_H3.3, PMID:20688500, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.3:H3K18bio" BROAD [HIstome_ptm_Hs:H3K18bio] synonym: "hH3.3/InitMet-/Btn:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P84243, 2-136, Lys-19, MOD:00126" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P84243 ! histone H3.3 (human) relationship: has_part MOD:00126 ! N6-biotinyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045209 name: histone H3.1, initiator methionine removed ADP-ribosylated 2 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been ADP-ribosylated at the position equivalent to Lys-38 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-38, MOD:01399." [HIstome_var_Hs:Histone_H3.1, PMID:20525793, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K37ar" BROAD [HIstome_ptm_Hs:H3K37ar] synonym: "hH3.1/InitMet-/ADPrib:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-38, MOD:01399" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:01399 ! N6-(ADP-ribosyl)-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045208 name: histone H3.1, initiator methionine removed citrullinated 3 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been citrullinated at the position equivalent to Arg-18 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Arg-18, MOD:00219." [HIstome_var_Hs:Histone_H3.1, PMID:15339660, PMID:15345777, PMID:17079667, PMID:18209087, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3R17ci" BROAD [HIstome_ptm_Hs:H3R17ci] synonym: "hH3.1/InitMet-/Cit:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Arg-18, MOD:00219" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5246534 "PR:000045208 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00219 ! L-citrulline relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045201 name: histone H3.1, initiator methionine removed acetylated 4 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-5 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-5, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:18552846, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K4ac" BROAD [HIstome_ptm_Hs:H3K4ac] synonym: "hH3.1/InitMet-/Ac:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-5, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568751 "PR:000045201 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045200 name: histone H3.1, initiator methionine removed trimethylated 1 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-28, MOD:00083." [HIstome_var_Hs:Histone_H3.1, PMID:12351676, PMID:12649488, PMID:16630819, PMID:17200670, PMID:17314394, PMID:18318442, PMID:18628788, PMID:18632628, PMID:18716661, PMID:19340297, PMID:19557159, PMID:19887624, PMID:21115743, PMID:21228036, PMID:21242977, PMID:21512140, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K27me3" BROAD [HIstome_ptm_Hs:H3K27me3] synonym: "hH3.1/InitMet-/Me3:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-28, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-212220 "PR:000045200 located_in GO:0005654" xref: Reactome:R-HSA-4754169 "PR:000045200 located_in GO:0005654" xref: TDR:3379 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045203 name: histone H3.1, initiator methionine removed monomethylated 6 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-80, MOD:00085." [HIstome_var_Hs:Histone_H3.1, PMID:20699226, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K79me1" BROAD [HIstome_ptm_Hs:H3K79me1] synonym: "hH3.1/InitMet-/Me1:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-80, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5649791 "PR:000045203 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045202 name: histone H3.1, initiator methionine removed monomethylated 5 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been monomethylated at the position equivalent to Lys-28 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-28, MOD:00085." [HIstome_var_Hs:Histone_H3.1, PMID:17030614, PMID:17512414, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K27me1" BROAD [HIstome_ptm_Hs:H3K27me1] synonym: "hH3.1/InitMet-/Me1:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-28, MOD:00085" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5638327 "PR:000045202 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00085 ! N6-methyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045205 name: histone H3.1, initiator methionine removed trimethylated 3 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been trimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-80, MOD:00083." [HIstome_var_Hs:Histone_H3.1, PMID:12628190, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K79me3" BROAD [HIstome_ptm_Hs:H3K79me3] synonym: "hH3.1/InitMet-/Me3:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-80, MOD:00083" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5649795 "PR:000045205 located_in GO:0005654" xref: TDR:1805 is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00083 ! N6,N6,N6-trimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045204 name: histone H3.1, initiator methionine removed dimethylated 4 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been dimethylated at the position equivalent to Lys-80 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-80, MOD:00084." [HIstome_var_Hs:Histone_H3.1, PMID:12123582, PMID:16307923, PMID:20699226, PMID:21741597, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K79me2" BROAD [HIstome_ptm_Hs:H3K79me2] synonym: "hH3.1/InitMet-/Me2:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-80, MOD:00084" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5649768 "PR:000045204 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00084 ! N6,N6-dimethyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045207 name: histone H3.1, initiator methionine removed acetylated 6 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-19 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-19, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:15988529, PMID:18552846, PMID:18953329, PMID:19349354, PMID:19349354, PMID:20841388, PMID:20978174, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K18ac" BROAD [HIstome_ptm_Hs:H3K18ac] synonym: "hH3.1/InitMet-/Ac:6" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-19, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568761 "PR:000045207 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:000045206 name: histone H3.1, initiator methionine removed acetylated 5 (human) def: "A histone H3.1 (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:P68431. UniProtKB:P68431, 2-136, Lys-10, MOD:00064." [HIstome_var_Hs:Histone_H3.1, PMID:12419248, PMID:16544193, PMID:17403718, PMID:17478518, PMID:17906200, PMID:18337721, PMID:19135889, PMID:20816089, PMID:20972224, PMID:21453398, PRO:DAN, PRO:JPB, PRO:JR] comment: Category=organism-modification. synonym: "H3.1:H3K9ac" BROAD [HIstome_ptm_Hs:H3K9ac] synonym: "hH3.1/InitMet-/Ac:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P68431, 2-136, Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-4568939 "PR:000045206 located_in GO:0005654" is_a: PR:P68431 ! histone H3.1 (human) relationship: has_part MOD:00064 ! N6-acetyl-L-lysine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens relationship: lacks_part PR:000021937 ! initiator methionine