[Term]
id: PR:000027472
name: RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated 2
def: "A RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated form that is the actived form (see PR:000003103), which has been further phosphorylated by autocatalysis in trans at two sites that lie in the characteristic AKT substrate motif RxRxx[ST]. Example: UniProtKB:P31749-1, Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046." [PMID:16549426, PRO:PD]
comment: Category=modification.
synonym: "AKT1/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "Akt1 autophosphorylated" EXACT []
is_a: PR:000003102 ! RAC-alpha serine/threonine-protein kinase isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine