[Term]
id: PR:000027182
name: IRAK4:MYD88:TIRAP:activated TLR4 complex
def: "An IRAK4:MYD88:TIRAP:activated TLR complex that contains activated TLR4 receptor." [PMID:12297423, PRO:CNA, PRO:DAN, TLR:AMM]
comment: Category=complex. Requested by=TLR.
synonym: "IRAK4:MyD88:Mal:activated TLR4" EXACT []
is_a: PR:000027193 ! IRAK4:MYD88:TIRAP:activated TLR complex
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: has_component PR:000001155 {cardinality="2"} ! Toll-like receptor 4
relationship: has_component PR:000001740 {cardinality="2"} ! myeloid differentiation primary response protein MyD88
relationship: has_component PR:000001751 {cardinality="2"} ! Toll/interleukin-1 receptor domain-containing adapter protein
relationship: has_component PR:000001780 ! interleukin-1 receptor-associated kinase 4
relationship: has_component PR:000003296 {cardinality="2"} ! lymphocyte antigen 96