[Term]
id: PR:000026124
name: PLP-dependent alpha-oxoamine synthase
def: "A protein that consist of a single copy of the Aminotransferase class I and II (Pfam:PF00155) domain. Alpha-oxoamine synthase corresponds to the alpha-division of pyridoxal-5'-phosphate (PLP)-dependent enzymes. Alpha-oxoamine synthase are involved in catalysis of the decarboxylative condensation of a carboxylic acid coenzyme A (CoA) thioester and an amino acid, with the amino acid being covalently bound to the PLP via a Schiff base at the beginning of the catalytic cycle." [PMID:15189147, PMID:17559874, PRO:CNA]
comment: Category=family.
synonym: "OAS" EXACT []
synonym: "POAS" EXACT []
synonym: "alpha-oxoamine synthase" EXACT []
xref: PIRSF:PIRSF800003
is_a: PR:000000001 ! protein