[Term]
id: PR:000025784
name: MYD88:TIRAP:activated TLR4 receptor
def: "A MYD88:TIRAP:activated TLR complex whose activated TLR component is TLR4 receptor." [PMID:16751103, PRO:CNA, PRO:DAN, TLR:AMM]
comment: Category=complex. Requested by=TLR.
synonym: "MYD88:Mal:activated TLR4 receptor" EXACT []
synonym: "MyD88:Mal complexed with the activated TLR4 receptor" EXACT []
is_a: PR:000025774 ! MYD88:TIRAP:activated TLR complex
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: has_component PR:000001155 {cardinality="2"} ! Toll-like receptor 4
relationship: has_component PR:000001740 {cardinality="2"} ! myeloid differentiation primary response protein MyD88
relationship: has_component PR:000001751 {cardinality="2"} ! Toll/interleukin-1 receptor domain-containing adapter protein
relationship: has_component PR:000003296 {cardinality="2"} ! lymphocyte antigen 96

[Term]
id: PR:000037475
name: MYD88:TIRAP:activated TLR4 receptor (chicken)
def: "A MYD88:TIRAP:activated TLR4 receptor whose components are encoded in the genome of chicken." [Reactome:R-GGA-433821]
comment: Category=organism-complex. Requested by=TLR.
synonym: "chick-(MYD88:TIRAP:TLR4actv)" EXACT PRO-short-label [PRO:DAN]
synonym: "MYD88:MAL:LY96:TLR4:LPS complex (chicken)" EXACT []
synonym: "MYD88:MAL:activated TLR4 receptor (chicken)" EXACT []
is_a: PR:000025784 ! MYD88:TIRAP:activated TLR4 receptor
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus
relationship: has_component PR:A0A1D5NZX9 {cardinality="2"} ! lymphocyte antigen 96 (chicken)
relationship: has_component PR:A5HNF6 {cardinality="2"} ! myeloid differentiation primary response protein MyD88 (chicken)
relationship: has_component PR:Q4U127 {cardinality="2"} ! Toll-interleukin 1 receptor domain-containing adaptor protein (chicken)
relationship: has_component PR:Q7ZTG5 {cardinality="2"} ! Toll-like receptor 4 (chicken)

[Term]
id: PR:000027175
name: MYD88l:TIRAP:activated TLR4 receptor (mouse)
def: "A MYD88:TIRAP:activated TLR4 receptor whose components are encoded in the genome of mouse.This complex contains the long isoform of Myd88." [PMID:16751103, TLR:AMM]
comment: Category=organism-complex. Requested by=TLR.
synonym: "TLR4MD2LPSditm" EXACT [TLR:AMM]
synonym: "MyD88l:Mal:activated TLR4 receptor (mouse)" EXACT []
is_a: PR:000025784 ! MYD88:TIRAP:activated TLR4 receptor
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_component PR:000027171 {cardinality="2"} ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:000027172 {cardinality="2"} ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:P22366-1 {cardinality="2"} ! myeloid differentiation primary response protein MyD88 isoform 1 (mouse)
relationship: has_component PR:Q99JY1 {cardinality="2"} ! Toll/interleukin-1 receptor domain-containing adapter protein (mouse)

[Term]
id: PR:000027174
name: MYD88s:TIRAP:activated TLR4 receptor (mouse)
def: "A MYD88:TIRAP:activated TLR4 receptor whose components are encoded in the genome of mouse. This complex contains the short isoform of MYD88." [PMID:12538665, TLR:AMM]
comment: Category=organism-complex. Requested by=TLR.
synonym: "TLR4MD2LPSditms" EXACT [TLR:AMM]
synonym: "MYD88s:Mal:activated TLR4 receptor (mouse)" EXACT []
is_a: PR:000025784 ! MYD88:TIRAP:activated TLR4 receptor
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_component PR:000027171 {cardinality="2"} ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:000027172 {cardinality="2"} ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
relationship: has_component PR:P22366-2 {cardinality="2"} ! myeloid differentiation primary response protein MyD88 isoform 2 (mouse)
relationship: has_component PR:Q99JY1 {cardinality="2"} ! Toll/interleukin-1 receptor domain-containing adapter protein (mouse)