[Term]
id: PR:000021978
name: interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4
def: "An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation occurs by interleukin-1 receptor-associated kinase 4 (IRAK-4) and extensively autophosphorylated in the Pro-, Ser-, and Thr-rich ProST region between the N-terminal death domain and kinase domain. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "hp-IRAK1" EXACT []
synonym: "IRAK1/iso:1/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "interleukin-1 receptor-associated kinase 1 hyperphosphorylated" EXACT []
is_a: PR:000021971 ! interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine