[Term]
id: PR:000049719
name: tyrosine-protein kinase Yes, initiator methionine removed form (human)
def: "A tyrosine-protein kinase Yes (human) that has had the initiator methionine removed. UniProtKB:P07947, 2-543." [PRO:DNx, Reactome:R-HSA-373640]
comment: Category=organism-modification.
synonym: "PRO_0000088181" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hYES1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07947, 2-543" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-373640 "PR:000049719 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P07947 ! tyrosine-protein kinase Yes (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000017528
name: tyrosine-protein kinase Yes
def: "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human YES1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "YES" RELATED Gene-based []
synonym: "YES1" EXACT PRO-short-label [PRO:DNx]
synonym: "p61-Yes" EXACT []
synonym: "proto-oncogene c-Yes" EXACT []
synonym: "proto-oncogene tyrosine-protein kinase Yes" EXACT []
xref: IUPHARobj:2284
is_a: PR:000002997 ! proto-oncogene SRC-like tyrosine-protein kinase

[Term]
id: PR:P07947
name: tyrosine-protein kinase Yes (human)
def: "A tyrosine-protein kinase Yes that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07947]
comment: Category=organism-gene.
synonym: "YES" RELATED Gene-based [UniProtKB:P07947]
synonym: "YES1" RELATED Gene-based [UniProtKB:P07947]
synonym: "hYES1" EXACT PRO-short-label [PRO:DNx]
synonym: "p61-Yes (human)" EXACT [UniProtKB:P07947]
synonym: "proto-oncogene c-Yes (human)" EXACT [UniProtKB:P07947]
xref: DTO:03100571
xref: UniProtKB:P07947
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017528 ! tyrosine-protein kinase Yes
relationship: has_gene_template HGNC:12841 ! YES1 (human)

[Term]
id: PR:000045651
name: tyrosine-protein kinase Yes phosphorylated 1 (human)
def: "A tyrosine-protein kinase Yes (human) that has been phosphorylated at Tyr-537. UniProtKB:P07947, Tyr-537, MOD:00048." [PMID:7690925, iPTMnet:P07947]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:7690925). Status=unreviewed.
synonym: "hYES1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07947, Tyr-537, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P07947 ! tyrosine-protein kinase Yes (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens