[Term]
id: PR:000017508
name: X-ray repair cross-complementing protein 5
def: "A protein that is a translation product of the human XRCC5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Ku80" EXACT []
synonym: "Ku86" EXACT []
synonym: "TLAA" RELATED []
synonym: "CTC85" EXACT []
synonym: "CTCBF" RELATED []
synonym: "G22P2" RELATED Gene-based []
synonym: "XRCC5" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor IV" EXACT []
synonym: "DNA repair protein XRCC5" EXACT []
synonym: "thyroid-lupus autoantigen" RELATED []
synonym: "86 kDa subunit of Ku antigen" EXACT []
synonym: "lupus Ku autoantigen protein p86" EXACT []
synonym: "Ku autoantigen protein p86 homolog" EXACT []
synonym: "CTC box-binding factor 85 kDa subunit" EXACT []
synonym: "ATP-dependent DNA helicase 2 subunit 2" EXACT []
synonym: "ATP-dependent DNA helicase II 80 kDa subunit" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9HGM8
name: ATP-dependent DNA helicase II subunit 2 (Schizosaccharomyces pombe 972h-)
def: "An X-ray repair cross-complementing protein 5 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q9HGM8, PANTHER:PTHR12604:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "ku80" RELATED Gene-based [UniProtKB:Q9HGM8]
synonym: "pku80" RELATED Gene-based [UniProtKB:Q9HGM8]
synonym: "SPBC543.03c" RELATED Gene-based [UniProtKB:Q9HGM8]
synonym: "Spom972h-XRCC5" EXACT PRO-short-label [PRO:DNx]
synonym: "pombe Ku80 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9HGM8]
synonym: "ATP-dependent DNA helicase II subunit Ku80 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q9HGM8]
xref: UniProtKB:Q9HGM8
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000017508 ! X-ray repair cross-complementing protein 5
relationship: has_gene_template PomBase:SPBC543.03c ! pku80 (Schizosaccharomyces pombe)

[Term]
id: PR:Q9FQ09
name: ATP-dependent DNA helicase 2 subunit KU80 (Arabidopsis thaliana)
def: "An X-ray repair cross-complementing protein 5 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9FQ09, PANTHER:PTHR12604:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "KU80" RELATED Gene-based [UniProtKB:Q9FQ09]
synonym: "T2J15.4" RELATED Gene-based [UniProtKB:Q9FQ09]
synonym: "At-XRCC5" EXACT PRO-short-label [PRO:DNx]
synonym: "At1g48050" RELATED Gene-based [UniProtKB:Q9FQ09]
synonym: "F21D18.26" RELATED Gene-based [UniProtKB:Q9FQ09]
synonym: "ATP-dependent DNA helicase 2 subunit 2 (Arabidopsis thaliana)" EXACT [UniProtKB:Q9FQ09]
synonym: "ATP-dependent DNA helicase II 80 kDa subunit (Arabidopsis thaliana)" EXACT [UniProtKB:Q9FQ09]
xref: UniProtKB:Q9FQ09
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000017508 ! X-ray repair cross-complementing protein 5
relationship: has_gene_template Araport:AT1G48050 ! KU80 (Arabidopsis thaliana)

[Term]
id: PR:Q54LY5
name: X-ray repair cross-complementing protein 5 (Dictyostelium discoideum)
def: "An X-ray repair cross-complementing protein 5 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54LY5, PANTHER:PTHR12604:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "ku80" RELATED Gene-based [UniProtKB:Q54LY5]
synonym: "Dicty-XRCC5" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0286303" RELATED Gene-based [UniProtKB:Q54LY5]
synonym: "ATP-dependent DNA helicase 2 subunit ku80 (Dictyostelium discoideum)" EXACT [UniProtKB:Q54LY5]
xref: UniProtKB:Q54LY5
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000017508 ! X-ray repair cross-complementing protein 5
relationship: has_gene_template dictyBase:DDB_G0286303 ! ku80 (Dictyostelium discoideum)

[Term]
id: PR:P27641
name: X-ray repair cross-complementing protein 5 (mouse)
def: "An X-ray repair cross-complementing protein 5 that is encoded in the genome of mouse." [OMA:P27641, PRO:DNx]
comment: Category=organism-gene.
synonym: "G22p2" RELATED Gene-based [UniProtKB:P27641]
synonym: "Xrcc5" RELATED Gene-based [UniProtKB:P27641]
synonym: "mXRCC5" EXACT PRO-short-label [PRO:DNx]
synonym: "Ku80 (mouse)" EXACT [UniProtKB:P27641]
synonym: "CTC85 (mouse)" EXACT [UniProtKB:P27641]
synonym: "CTCBF (mouse)" RELATED [UniProtKB:P27641]
synonym: "nuclear factor IV (mouse)" EXACT [UniProtKB:P27641]
synonym: "DNA repair protein XRCC5 (mouse)" EXACT [UniProtKB:P27641]
synonym: "Ku autoantigen protein p86 homolog (mouse)" EXACT [UniProtKB:P27641]
synonym: "CTC box-binding factor 85 kDa subunit (mouse)" EXACT [UniProtKB:P27641]
synonym: "ATP-dependent DNA helicase 2 subunit 2 (mouse)" EXACT [UniProtKB:P27641]
synonym: "ATP-dependent DNA helicase II 80 kDa subunit (mouse)" EXACT [UniProtKB:P27641]
xref: UniProtKB:P27641
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000017508 ! X-ray repair cross-complementing protein 5
relationship: has_gene_template MGI:104517 ! Xrcc5 (mouse)

[Term]
id: PR:000049713
name: X-ray repair cross-complementing protein 5, initiator methionine removed form (human)
def: "An X-ray repair cross-complementing protein 5 (human) that has had the initiator methionine removed. UniProtKB:P13010, 2-732." [PRO:DNx, Reactome:R-HSA-3134849, Reactome:R-HSA-58274]
comment: Category=organism-modification.
synonym: "PRO_0000084340" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hXRCC5/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P13010, 2-732" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-58274 "PR:000049713 located_in GO:0005654"
xref: Reactome:R-HSA-3134849 "PR:000049713 located_in GO:0005829"
xref: Reactome:R-HSA-6801297 "PR:000049713 located_in GO:0034774"
xref: Reactome:R-HSA-6806530 "PR:000049713 located_in GO:0005576"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P13010 ! X-ray repair cross-complementing protein 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000021863
name: X-ray repair cross-complementing protein 5, initiator methionine removed form
def: "An X-ray repair cross-complementing protein 5 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "XRCC5/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000017508 ! X-ray repair cross-complementing protein 5
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:P13010
name: X-ray repair cross-complementing protein 5 (human)
def: "An X-ray repair cross-complementing protein 5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P13010]
comment: Category=organism-gene.
synonym: "G22P2" RELATED Gene-based [UniProtKB:P13010]
synonym: "XRCC5" RELATED Gene-based [UniProtKB:P13010]
synonym: "hXRCC5" EXACT PRO-short-label [PRO:DNx]
synonym: "Ku80 (human)" EXACT [UniProtKB:P13010]
synonym: "Ku86 (human)" EXACT [UniProtKB:P13010]
synonym: "TLAA (human)" BROAD [UniProtKB:P13010]
synonym: "CTC85 (human)" EXACT [UniProtKB:P13010]
synonym: "CTCBF (human)" BROAD [UniProtKB:P13010]
synonym: "nuclear factor IV (human)" EXACT [UniProtKB:P13010]
synonym: "DNA repair protein XRCC5 (human)" EXACT [UniProtKB:P13010]
synonym: "thyroid-lupus autoantigen (human)" BROAD [UniProtKB:P13010]
synonym: "86 kDa subunit of Ku antigen (human)" EXACT [UniProtKB:P13010]
synonym: "lupus Ku autoantigen protein p86 (human)" EXACT [UniProtKB:P13010]
synonym: "CTC box-binding factor 85 kDa subunit (human)" EXACT [UniProtKB:P13010]
synonym: "ATP-dependent DNA helicase 2 subunit 2 (human)" EXACT [UniProtKB:P13010]
synonym: "ATP-dependent DNA helicase II 80 kDa subunit (human)" EXACT [UniProtKB:P13010]
synonym: "X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) (human)" EXACT [UniProtKB:P13010]
xref: UniProtKB:P13010
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017508 ! X-ray repair cross-complementing protein 5
relationship: has_gene_template HGNC:12833 ! XRCC5 (human)