[Term]
id: PR:Q9H4A3
name: serine/threonine-protein kinase WNK1 (human)
def: "A serine/threonine-protein kinase WNK1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H4A3]
comment: Category=organism-gene.
synonym: "KDP" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "HSN2" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "WNK1" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "hWNK1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRKWNK1" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "KIAA0344" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "p65 (human)" BROAD [UniProtKB:Q9H4A3]
synonym: "kinase deficient protein (human)" EXACT [UniProtKB:Q9H4A3]
synonym: "erythrocyte 65 kDa protein (human)" EXACT [UniProtKB:Q9H4A3]
synonym: "protein kinase with no lysine 1 (human)" EXACT [UniProtKB:Q9H4A3]
synonym: "protein kinase lysine-deficient 1 (human)" EXACT [UniProtKB:Q9H4A3]
xref: UniProtKB:Q9H4A3
xref: Reactome:R-HSA-2672391 "PR:Q9H4A3 located_in GO:0005829"
xref: DTO:03100567
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017431 ! serine/threonine-protein kinase WNK1
relationship: has_gene_template HGNC:14540 ! WNK1 (human)

[Term]
id: PR:000017431
name: serine/threonine-protein kinase WNK1
def: "A protein that is a translation product of the human WNK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "KDP" RELATED Gene-based []
synonym: "p65" BROAD [PRO:DNx]
synonym: "HSN2" RELATED Gene-based []
synonym: "WNK1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRKWNK1" RELATED Gene-based []
synonym: "KIAA0344" RELATED Gene-based []
synonym: "protein HSN2" RELATED []
synonym: "kinase deficient protein" EXACT []
synonym: "erythrocyte 65 kDa protein" EXACT []
synonym: "protein kinase with no lysine 1" EXACT []
synonym: "protein kinase lysine-deficient 1" EXACT []
xref: IUPHARobj:2280
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9H4A3-7
name: serine/threonine-protein kinase WNK1 isoform h6 (human)
def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-7." [PRO:DNx, UniProtKB:Q9H4A3]
comment: Category=organism-sequence.
synonym: "hWNK1/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H4A3-7
is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H4A3-4
name: serine/threonine-protein kinase WNK1, kidney-specific isoform (human)
def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-4." [PRO:DNx, UniProtKB:Q9H4A3]
comment: Category=organism-sequence.
synonym: "hWNK1/iso:k" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase WNK1 isoform KS-WNK1 (human)" EXACT [UniProtKB:Q9H4A3]
synonym: "serine/threonine-protein kinase WNK1 isoform Kidney-Specific (human)" EXACT [UniProtKB:Q9H4A3]
xref: UniProtKB:Q9H4A3-4
is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H4A3-5
name: serine/threonine-protein kinase WNK1 isoform h4 (human)
def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-5." [PMID:15060842, PRO:CNA, PRO:DAN]
comment: Category=organism-sequence.
synonym: "hWNK1/iso:h4" EXACT PRO-short-label [PRO:DAN]
synonym: "WNK1 brain and spinal cord variant" RELATED []
synonym: "serine/threonine-protein kinase WNK1 isoform 4" RELATED Gene-based [UniProtKB:Q9H4A3]
xref: UniProtKB:Q9H4A3-5
is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H4A3-2
name: serine/threonine-protein kinase WNK1 isoform h2 (human)
def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-2." [PRO:DNx, UniProtKB:Q9H4A3]
comment: Category=organism-sequence.
synonym: "hWNK1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9H4A3-2
is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H4A3-1
name: serine/threonine-protein kinase WNK1 isoform h1 (human)
def: "A serine/threonine-protein kinase WNK1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H4A3-1." [PRO:DNx, UniProtKB:Q9H4A3]
comment: Category=organism-sequence.
synonym: "hWNK1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase WNK1 isoform L-WNK1 (human)" EXACT [UniProtKB:Q9H4A3]
xref: UniProtKB:Q9H4A3-1
is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9H4A3-6
name: serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform (human)
def: "A serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform that is encoded in the genome of human." [PMID:15060842, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hWNK1/iso:drgsn" EXACT PRO-short-label [PRO:DAN]
synonym: "WNK1 DRG and sciatic nerve variant" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "serine/threonine-protein kinase WNK1 isoform 5" RELATED Gene-based [UniProtKB:Q9H4A3]
synonym: "WNK1 dorsal root ganglia and sciatic nerve variant" RELATED Gene-based [UniProtKB:Q9H4A3]
xref: UniProtKB:Q9H4A3-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037201 ! serine/threonine-protein kinase WNK1, dorsal root ganglia and sciatic nerve isoform

[Term]
id: PR:000046059
name: serine/threonine-protein kinase WNK1 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase WNK1 (human) that has been phosphorylated at the position equivalent to Thr-60 of the amino acid sequence represented by UniProtKB:Q9H4A3-1. Example: UniProtKB:Q9H4A3-1, Thr-60, MOD:00047." [PMID:14611643, iPTMnet:Q9H4A3]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14611643). Status=unreviewed.
synonym: "hWNK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9H4A3-1, Thr-60, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9H4A3 ! serine/threonine-protein kinase WNK1 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens