[Term] id: PR:000017369 name: tryptophan--tRNA ligase, cytoplasmic def: "A protein that is a translation product of the human WARS1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "WRS" RELATED Gene-based [] synonym: "WARS" RELATED Gene-based [] synonym: "IFI53" RELATED Gene-based [] synonym: "IFP53" EXACT [] synonym: "TrpRS" BROAD [PRO:DAN] synonym: "WARS1" EXACT PRO-short-label [PRO:DNx] synonym: "tryptophan--tRNA ligase" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase" BROAD [PRO:DAN] synonym: "interferon-induced protein 53" EXACT [] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P23381-1 name: tryptophan--tRNA ligase, cytoplasmic isoform h1 (human) def: "A tryptophan--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23381-1." [PRO:DNx, UniProtKB:P23381] comment: Category=organism-sequence. synonym: "hWARS1/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P23381-1 is_a: PR:P23381 ! tryptophan--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P23381-2 name: tryptophan--tRNA ligase, cytoplasmic isoform h2 (human) def: "A tryptophan--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23381-2." [PRO:DNx, UniProtKB:P23381] comment: Category=organism-sequence. synonym: "hWARS1/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "tryptophan--tRNA ligase, cytoplasmic isoform mini TrpRS (human)" EXACT [UniProtKB:P23381] xref: UniProtKB:P23381-2 is_a: PR:P23381 ! tryptophan--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9SR15-1 name: tryptophan--tRNA ligase, cytoplasmic isoform 1 (Arabidopsis thaliana) def: "A tryptophan--tRNA ligase, cytoplasmic (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9SR15-1." [PRO:DNx, UniProtKB:Q9SR15] comment: Category=organism-sequence. synonym: "At-WARS/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9SR15-1 is_a: PR:Q9SR15 ! tryptophan--tRNA ligase, cytoplasmic (Arabidopsis thaliana) relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana [Term] id: PR:000039304 name: tryptophan--tRNA ligase, cytoplasmic isoform 1 def: "A tryptophan--tRNA ligase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32921-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "WARS/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic [Term] id: PR:Q6P7B0 name: tryptophan--tRNA ligase, cytoplasmic (rat) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of rat." [OMA:Q6P7B0, PRO:DNx] comment: Category=organism-gene. synonym: "Wars" RELATED Gene-based [UniProtKB:Q6P7B0] synonym: "Wars1" RELATED Gene-based [UniProtKB:Q6P7B0] synonym: "rWARS" EXACT PRO-short-label [PRO:DNx] synonym: "TrpRS (rat)" BROAD [PRO:DAN, UniProtKB:Q6P7B0] synonym: "tryptophan--tRNA ligase (rat)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (rat)" BROAD [PRO:DAN, UniProtKB:Q6P7B0] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (rat)" EXACT [PRO:DAN] xref: UniProtKB:Q6P7B0 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template RGD:1308278 ! Wars (rat) [Term] id: PR:000021843 name: tryptophan--tRNA ligase, cytoplasmic proteolytic cleavage product def: "A tryptophan--tRNA ligase, cytoplasmic that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "WARS/ClvPrd" EXACT PRO-short-label [PRO:DNx] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic proteolytic cleavage product" EXACT [PRO:DAN] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic [Term] id: PR:000021842 name: tryptophan--tRNA ligase, cytoplasmic, initiator methionine removed form def: "A tryptophan--tRNA ligase, cytoplasmic that has had the initiator methionine removed." [PRO:DNx] comment: Category=modification. synonym: "WARS/InitMet-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic intersection_of: lacks_part PR:000021937 ! initiator methionine [Term] id: PR:P32921-2 name: tryptophan--tRNA ligase, cytoplasmic isoform m2 (mouse) def: "A tryptophan--tRNA ligase, cytoplasmic (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32921-2." [PRO:DNx, UniProtKB:P32921] comment: Category=organism-sequence. synonym: "mWARS/iso:m2" EXACT PRO-short-label [PRO:DNx] synonym: "tryptophan--tRNA ligase, cytoplasmic isoform Short (mouse)" EXACT [UniProtKB:P32921] xref: UniProtKB:P32921-2 is_a: PR:P32921 ! tryptophan--tRNA ligase, cytoplasmic (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:P32921-1 name: tryptophan--tRNA ligase, cytoplasmic isoform 1 (mouse) def: "A tryptophan--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mWARS/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "tryptophan--tRNA ligase, cytoplasmic isoform Long (mouse)" EXACT [UniProtKB:P32921] xref: UniProtKB:P32921-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039304 ! tryptophan--tRNA ligase, cytoplasmic isoform 1 [Term] id: PR:P23381 name: tryptophan--tRNA ligase, cytoplasmic (human) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P23381] comment: Category=organism-gene. synonym: "WRS" RELATED Gene-based [UniProtKB:P23381] synonym: "WARS" RELATED Gene-based [UniProtKB:P23381] synonym: "hWRS" EXACT [UniProtKB:P23381] synonym: "IFI53" RELATED Gene-based [UniProtKB:P23381] synonym: "WARS1" RELATED Gene-based [UniProtKB:P23381] synonym: "hWARS1" EXACT PRO-short-label [PRO:DNx] synonym: "IFP53 (human)" EXACT [UniProtKB:P23381] synonym: "TrpRS (human)" BROAD [PRO:DAN] synonym: "tryptophan--tRNA ligase (human)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (human)" BROAD [PRO:DAN] synonym: "interferon-induced protein 53 (human)" EXACT [UniProtKB:P23381] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (human)" EXACT [PRO:DAN] xref: UniProtKB:P23381 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template HGNC:12729 ! WARS1 (human) [Term] id: PR:P32921 name: tryptophan--tRNA ligase, cytoplasmic (mouse) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of mouse." [OMA:P32921, PRO:DNx] comment: Category=organism-gene. synonym: "Wrs" RELATED Gene-based [UniProtKB:P32921] synonym: "Wars" RELATED Gene-based [UniProtKB:P32921] synonym: "Wars1" RELATED Gene-based [UniProtKB:P32921] synonym: "mWARS" EXACT PRO-short-label [PRO:DNx] synonym: "TrpRS (mouse)" BROAD [PRO:DAN, UniProtKB:P32921] synonym: "tryptophan--tRNA ligase (mouse)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (mouse)" BROAD [PRO:DAN, UniProtKB:P32921] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (mouse)" EXACT [PRO:DAN] xref: UniProtKB:P32921 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template MGI:104630 ! Wars (mouse) [Term] id: PR:Q55DZ8 name: tryptophan--tRNA ligase, cytoplasmic (Dictyostelium discoideum) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55DZ8, PRO:DNx] comment: Category=organism-gene. synonym: "trpS" RELATED Gene-based [UniProtKB:Q55DZ8] synonym: "Dicty-WARS" EXACT PRO-short-label [PRO:DNx] synonym: "DDB_G0269454" RELATED Gene-based [UniProtKB:Q55DZ8] synonym: "TrpRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q55DZ8] synonym: "tryptophan--tRNA ligase (Dictyostelium discoideum)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q55DZ8] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (Dictyostelium discoideum)" EXACT [PRO:DAN] xref: UniProtKB:Q55DZ8 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template dictyBase:DDB_G0269454 ! trpS (Dictyostelium discoideum) [Term] id: PR:Q12109 name: tryptophan--tRNA ligase, cytoplasmic (yeast) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of yeast." [OMA:Q12109, PRO:DNx] comment: Category=organism-gene. synonym: "WRS1" RELATED Gene-based [UniProtKB:Q12109] synonym: "yWARS" EXACT PRO-short-label [PRO:DNx] synonym: "HRE432" RELATED Gene-based [UniProtKB:Q12109] synonym: "YOL097C" RELATED Gene-based [UniProtKB:Q12109] synonym: "TrpRS (yeast)" BROAD [PRO:DAN, UniProtKB:Q12109] synonym: "tryptophan--tRNA ligase (yeast)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (yeast)" BROAD [PRO:DAN, UniProtKB:Q12109] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (yeast)" EXACT [PRO:DAN] xref: UniProtKB:Q12109 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template SGD:S000005457 ! WRS1 (yeast) [Term] id: PR:000049667 name: tryptophan--tRNA ligase, cytoplasmic, initiator methionine removed form (human) def: "A tryptophan--tRNA ligase, cytoplasmic (human) that has had the initiator methionine removed. UniProtKB:P23381, 2-471." [PRO:DNx, Reactome:R-HSA-379603] comment: Category=organism-modification. synonym: "PRO_0000136738" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hWARS/InitMet-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P23381, 2-471" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-379603 "PR:000049667 located_in GO:0005829" intersection_of: lacks_part PR:000021937 ! initiator methionine intersection_of: PR:P23381 ! tryptophan--tRNA ligase, cytoplasmic (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6P7B0-1 name: tryptophan--tRNA ligase, cytoplasmic isoform 1 (rat) def: "A tryptophan--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rWARS/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6P7B0-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039304 ! tryptophan--tRNA ligase, cytoplasmic isoform 1 [Term] id: PR:Q09692 name: tryptophan--tRNA ligase, cytoplasmic (Schizosaccharomyces pombe 972h-) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q09692, PRO:DNx] comment: Category=organism-gene. synonym: "wrs1" RELATED Gene-based [UniProtKB:Q09692] synonym: "SPAC2F7.13c" RELATED Gene-based [UniProtKB:Q09692] synonym: "Spom972h-WARS" EXACT PRO-short-label [PRO:DNx] synonym: "TrpRS (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q09692] synonym: "tryptophan--tRNA ligase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q09692] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (Schizosaccharomyces pombe 972h-)" EXACT [PRO:DAN] xref: UniProtKB:Q09692 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template PomBase:SPAC2F7.13c ! wrs1 (Schizosaccharomyces pombe) [Term] id: PR:Q9SR15 name: tryptophan--tRNA ligase, cytoplasmic (Arabidopsis thaliana) def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9SR15, PRO:DNx] comment: Category=organism-gene. synonym: "At-WARS" EXACT PRO-short-label [PRO:DNx] synonym: "At3g04600" RELATED Gene-based [UniProtKB:Q9SR15] synonym: "TrpRS (Arabidopsis thaliana)" BROAD [UniProtKB:Q9SR15] synonym: "tryptophan--tRNA ligase (Arabidopsis thaliana)" BROAD [PRO:DAN] synonym: "tryptophanyl-tRNA synthetase (Arabidopsis thaliana)" BROAD [PRO:DAN, UniProtKB:Q9SR15] synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (Arabidopsis thaliana)" EXACT [PRO:DAN] xref: UniProtKB:Q9SR15 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic relationship: has_gene_template Araport:AT3G04600 ! At3g04600 (Arabidopsis thaliana)