[Term]
id: PR:P04818-3
name: thymidylate synthase isoform h3 (human)
def: "A thymidylate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04818-3." [PRO:DNx, UniProtKB:P04818]
comment: Category=organism-sequence.
synonym: "hTYMS/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "thymidylate synthase isoform delta2+3 (human)" EXACT [UniProtKB:P04818]
xref: UniProtKB:P04818-3
is_a: PR:P04818 ! thymidylate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P04818-2
name: thymidylate synthase isoform h2 (human)
def: "A thymidylate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04818-2." [PRO:DNx, UniProtKB:P04818]
comment: Category=organism-sequence.
synonym: "hTYMS/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "thymidylate synthase isoform delta4 (human)" EXACT [UniProtKB:P04818]
xref: UniProtKB:P04818-2
is_a: PR:P04818 ! thymidylate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P04818-1
name: thymidylate synthase isoform h1 (human)
def: "A thymidylate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04818-1." [PRO:DNx, UniProtKB:P04818]
comment: Category=organism-sequence.
synonym: "hTYMS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P04818-1
is_a: PR:P04818 ! thymidylate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016876
name: thymidylate synthase
def: "A protein that is a translation product of the human TYMS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TS" RELATED Gene-based []
synonym: "TYMS" EXACT PRO-short-label [PRO:DNx]
synonym: "thyA" RELATED [PRO:DNx]
synonym: "TSase" EXACT []
synonym: "OK/SW-cl.29" RELATED Gene-based []
xref: IUPHARobj:2642
is_a: PR:000000001 ! protein

[Term]
id: PR:000049572
name: thymidylate synthase, initiator methionine removed form (human)
def: "A thymidylate synthase (human) that has had the initiator methionine removed. UniProtKB:P04818, 2-313." [PRO:DNx, Reactome:R-HSA-613424, Reactome:R-HSA-73518]
comment: Category=organism-modification.
synonym: "PRO_0000140901" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTYMS/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P04818, 2-313" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-613424 "PR:000049572 located_in GO:0005654"
xref: Reactome:R-HSA-73518 "PR:000049572 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P04818 ! thymidylate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P04818
name: thymidylate synthase (human)
def: "A thymidylate synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04818]
comment: Category=organism-gene.
synonym: "TS" RELATED Gene-based [UniProtKB:P04818]
synonym: "TYMS" RELATED Gene-based [UniProtKB:P04818]
synonym: "hTYMS" EXACT PRO-short-label [PRO:DNx]
synonym: "OK/SW-cl.29" RELATED Gene-based [UniProtKB:P04818]
synonym: "TSase (human)" EXACT [UniProtKB:P04818]
xref: UniProtKB:P04818
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016876 ! thymidylate synthase
relationship: has_gene_template HGNC:12441 ! TYMS (human)