[Term]
id: PR:Q11094
name: twist-related protein (worm)
def: "A twist-related protein 1 that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "hlh-8" RELATED Gene-based [UniProtKB:Q11094]
synonym: "C02B8.4" RELATED Gene-based [UniProtKB:Q11094]
synonym: "CeTwist" EXACT [UniProtKB:Q11094]
synonym: "TWIST1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "helix-loop-helix protein 8 (worm)" EXACT [UniProtKB:Q11094]
xref: UniProtKB:Q11094
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000016846 ! twist-related protein 1
relationship: has_gene_template WormBase:WBGene00001953 ! hlh-8 (worm)

[Term]
id: PR:000027819
name: twist-related protein 1 isoform 1
def: "A twist-related protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26687-1 or a 1:1 ortholog thereof." [PMID:1840517, PRO:CNA]
comment: Category=sequence.
synonym: "TWIST1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016846 ! twist-related protein 1

[Term]
id: PR:000027824
name: twist-related protein 1 isoform 1 unphosphorylated form (mouse)
def: "A twist-related protein 1 isoform 1 unphosphorylated form in mouse." [PMID:1840517, PRO:HJD]
comment: Category=organism-modification.
synonym: "mTWIST1/iso:1/PhosRes-" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027823 ! twist-related protein 1 isoform 1 unphosphorylated form

[Term]
id: PR:P26687
name: twist-related protein 1 (mouse)
def: "A twist-related protein 1 that is encoded in the genome of mouse." [OMA:P26687, PRO:DNx]
comment: Category=organism-gene.
synonym: "Twist" RELATED Gene-based [UniProtKB:P26687]
synonym: "Twist1" RELATED Gene-based [UniProtKB:P26687]
synonym: "mTWIST1" EXACT PRO-short-label [PRO:DNx]
synonym: "M-twist (mouse)" EXACT [UniProtKB:P26687]
xref: UniProtKB:P26687
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016846 ! twist-related protein 1
relationship: has_gene_template MGI:98872 ! Twist1 (mouse)

[Term]
id: PR:Q15672
name: twist-related protein 1 (human)
def: "A twist-related protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15672]
comment: Category=organism-gene.
synonym: "TWIST" RELATED Gene-based [UniProtKB:Q15672]
synonym: "TWIST1" RELATED Gene-based [UniProtKB:Q15672]
synonym: "BHLHA38" RELATED Gene-based [UniProtKB:Q15672]
synonym: "H-twist" EXACT [UniProtKB:Q15672]
synonym: "hTWIST1" EXACT PRO-short-label [PRO:DNx]
synonym: "class A basic helix-loop-helix protein 38 (human)" EXACT [UniProtKB:Q15672]
xref: Reactome:R-HSA-445442 "PR:Q15672 located_in GO:0005654"
xref: UniProtKB:Q15672
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016846 ! twist-related protein 1
relationship: has_gene_template HGNC:12428 ! TWIST1 (human)

[Term]
id: PR:000027821
name: twist-related protein 1 isoform 1 phosphorylated 1
def: "A twist-related protein 1 isoform 1 that has been phosphorylated at the Ser and/or Thr residues within the KER[RQ]RTxS motif located at the N terminus of the bHLH domain. Example: UniProtKB:P26687-1, Thr-125, MOD:00047|Ser-127, MOD:00046." [PMID:21559426, PRO:HJD]
comment: Category=modification.
synonym: "TWIST1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027819 ! twist-related protein 1 isoform 1
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:P26687-1
name: twist-related protein 1 isoform 1 (mouse)
def: "A twist-related protein 1 isoform 1 that is encoded in the genome of mouse." [PMID:1840517, PRO:CNA]
comment: Category=organism-sequence.
synonym: "mTWIST1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P26687-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027819 ! twist-related protein 1 isoform 1

[Term]
id: PR:000027823
name: twist-related protein 1 isoform 1 unphosphorylated form
def: "A twist-related protein 1 isoform 1 that lacks phosphorylated residues." [PRO:CNA]
comment: Category=modification.
synonym: "TWIST1/iso:1/PhosRes-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000027819 ! twist-related protein 1 isoform 1

[Term]
id: PR:000027822
name: twist-related protein 1 isoform 1 phosphorylated 1 (mouse)
def: "A twist-related protein 1 isoform 1 phosphorylated 1 in mouse. Example: UniProtKB:P26687-1, Thr-125, MOD:00047|Ser-127, MOD:00046." [PMID:21559426, PRO:HJD]
comment: Category=organism-modification. Kinase=("AKT1"; PR:P31750).
synonym: "mTWIST1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P26687-1, Thr-125, MOD:00047|Ser-127, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:000027821 ! twist-related protein 1 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000016846
name: twist-related protein 1
def: "A twist-related protein that is a translation product of the human TWIST1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TWIST" RELATED Gene-based []
synonym: "TWIST1" EXACT PRO-short-label [PRO:DNx]
synonym: "BHLHA38" RELATED Gene-based []
synonym: "bHLHa38" EXACT []
synonym: "class A basic helix-loop-helix protein 38" EXACT []
is_a: PR:000027825 ! twist-related protein

[Term]
id: PR:P10627
name: protein twist (fruit fly)
def: "A twist-related protein 1 that is encoded in the genome of fruit fly." [PRO:DNx]
comment: Category=organism-gene.
synonym: "twi" RELATED Gene-based [UniProtKB:P10627]
synonym: "CG2956" RELATED Gene-based [UniProtKB:P10627]
synonym: "fly-TWIST1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10627
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000016846 ! twist-related protein 1
relationship: has_gene_template FlyBase:FBgn0003900 ! twi (fruit fly)