[Term]
id: PR:000016802
name: tyrosyl-DNA phosphodiesterase 2
def: "A protein that is a translation product of the human TDP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EAP2" RELATED Gene-based []
synonym: "TDP2" EXACT PRO-short-label [PRO:DNx]
synonym: "EAPII" EXACT []
synonym: "TTRAP" RELATED Gene-based []
synonym: "AD-022" RELATED Gene-based []
synonym: "ETS1-associated protein 2" EXACT []
synonym: "ETS1-associated protein II" EXACT []
synonym: "Tyr-DNA phosphodiesterase 2" EXACT []
synonym: "5'-Tyr-DNA phosphodiesterase" EXACT []
synonym: "5'-tyrosyl-DNA phosphodiesterase" EXACT []
synonym: "TRAF and TNF receptor-associated protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q3T1H5
name: tyrosyl-DNA phosphodiesterase 2 (rat)
def: "A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of rat." [PANTHER:PTHR15822:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tdp2" RELATED Gene-based [UniProtKB:Q3T1H5]
synonym: "Ttrap" RELATED Gene-based [UniProtKB:Q3T1H5]
synonym: "rTDP2" EXACT PRO-short-label [PRO:DNx]
synonym: "Tyr-DNA phosphodiesterase 2 (rat)" EXACT [UniProtKB:Q3T1H5]
synonym: "5'-Tyr-DNA phosphodiesterase (rat)" EXACT [UniProtKB:Q3T1H5]
synonym: "5'-tyrosyl-DNA phosphodiesterase (rat)" EXACT [UniProtKB:Q3T1H5]
synonym: "TRAF and TNF receptor-associated protein (rat)" EXACT [UniProtKB:Q3T1H5]
xref: UniProtKB:Q3T1H5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016802 ! tyrosyl-DNA phosphodiesterase 2
relationship: has_gene_template RGD:1560342 ! Tdp2 (rat)

[Term]
id: PR:F1NW29
name: tyrosyl-DNA phosphodiesterase 2 (chicken)
def: "A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of chicken." [OMA:F1NW29, PRO:DNx]
comment: Category=organism-gene.
synonym: "TDP2" RELATED Gene-based [UniProtKB:F1NW29]
synonym: "chick-TDP2" EXACT PRO-short-label [PRO:DNx]
synonym: "Tyr-DNA phosphodiesterase 2 (chicken)" EXACT [UniProtKB:F1NW29]
synonym: "5'-Tyr-DNA phosphodiesterase (chicken)" EXACT [UniProtKB:F1NW29]
synonym: "5'-tyrosyl-DNA phosphodiesterase (chicken)" EXACT [UniProtKB:F1NW29]
xref: UniProtKB:F1NW29
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000016802 ! tyrosyl-DNA phosphodiesterase 2
relationship: has_gene_template NCBIGene:421007 ! TDP2 (chicken)

[Term]
id: PR:O95551
name: tyrosyl-DNA phosphodiesterase 2 (human)
def: "A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O95551]
comment: Category=organism-gene.
synonym: "EAP2" RELATED Gene-based [UniProtKB:O95551]
synonym: "TDP2" RELATED Gene-based [UniProtKB:O95551]
synonym: "TTRAP" RELATED Gene-based [UniProtKB:O95551]
synonym: "hTDP2" EXACT PRO-short-label [PRO:DNx]
synonym: "AD-022" RELATED Gene-based [UniProtKB:O95551]
synonym: "EAPII (human)" EXACT [UniProtKB:O95551]
synonym: "VPg unlinkase (human)" EXACT [UniProtKB:O95551]
synonym: "ETS1-associated protein 2 (human)" EXACT [UniProtKB:O95551]
synonym: "ETS1-associated protein II (human)" EXACT [UniProtKB:O95551]
synonym: "Tyr-DNA phosphodiesterase 2 (human)" EXACT [UniProtKB:O95551]
synonym: "5'-Tyr-DNA phosphodiesterase (human)" EXACT [UniProtKB:O95551]
synonym: "tyrosyl-RNA phosphodiesterase (human)" EXACT [UniProtKB:O95551]
synonym: "5'-tyrosyl-DNA phosphodiesterase (human)" EXACT [UniProtKB:O95551]
synonym: "TRAF and TNF receptor-associated protein (human)" EXACT [UniProtKB:O95551]
xref: Reactome:R-HSA-5687253 "PR:O95551 located_in GO:0005654"
xref: UniProtKB:O95551
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016802 ! tyrosyl-DNA phosphodiesterase 2
relationship: has_gene_template HGNC:17768 ! TDP2 (human)

[Term]
id: PR:Q5XJA0
name: tyrosyl-DNA phosphodiesterase 2 (zebrafish)
def: "A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of zebrafish." [OMA:Q5XJA0, PRO:DNx]
comment: Category=organism-gene.
synonym: "tdp2" RELATED Gene-based [UniProtKB:Q5XJA0]
synonym: "tdp2b" RELATED Gene-based [UniProtKB:Q5XJA0]
synonym: "ttrap" RELATED Gene-based [UniProtKB:Q5XJA0]
synonym: "ttrapl" RELATED Gene-based [UniProtKB:Q5XJA0]
synonym: "z-TDP2" EXACT PRO-short-label [PRO:DNx]
synonym: "si:ch211-81e5.5" RELATED Gene-based [UniProtKB:Q5XJA0]
synonym: "Tyr-DNA phosphodiesterase 2 (zebrafish)" EXACT [UniProtKB:Q5XJA0]
synonym: "5'-Tyr-DNA phosphodiesterase (zebrafish)" EXACT [UniProtKB:Q5XJA0]
synonym: "5'-tyrosyl-DNA phosphodiesterase (zebrafish)" EXACT [UniProtKB:Q5XJA0]
synonym: "TRAF and TNF receptor-associated protein homolog (zebrafish)" EXACT [UniProtKB:Q5XJA0]
xref: UniProtKB:Q5XJA0
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000016802 ! tyrosyl-DNA phosphodiesterase 2
relationship: has_gene_template ZFIN:ZDB-GENE-050816-1 ! tdp2b (zebrafish)

[Term]
id: PR:Q9JJX7
name: tyrosyl-DNA phosphodiesterase 2 (mouse)
def: "A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of mouse." [OMA:Q9JJX7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tdp2" RELATED Gene-based [UniProtKB:Q9JJX7]
synonym: "Ttrap" RELATED Gene-based [UniProtKB:Q9JJX7]
synonym: "mTDP2" EXACT PRO-short-label [PRO:DNx]
synonym: "Tyr-DNA phosphodiesterase 2 (mouse)" EXACT [UniProtKB:Q9JJX7]
synonym: "5'-Tyr-DNA phosphodiesterase (mouse)" EXACT [UniProtKB:Q9JJX7]
synonym: "5'-tyrosyl-DNA phosphodiesterase (mouse)" EXACT [UniProtKB:Q9JJX7]
synonym: "TRAF and TNF receptor-associated protein (mouse)" EXACT [UniProtKB:Q9JJX7]
xref: UniProtKB:Q9JJX7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016802 ! tyrosyl-DNA phosphodiesterase 2
relationship: has_gene_template MGI:1860486 ! Tdp2 (mouse)

[Term]
id: PR:O95551-1
name: tyrosyl-DNA phosphodiesterase 2 isoform h1 (human)
def: "A tyrosyl-DNA phosphodiesterase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95551-1." [PRO:DNx, UniProtKB:O95551]
comment: Category=organism-sequence.
synonym: "hTDP2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95551-1
is_a: PR:O95551 ! tyrosyl-DNA phosphodiesterase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95551-2
name: tyrosyl-DNA phosphodiesterase 2 isoform h2 (human)
def: "A tyrosyl-DNA phosphodiesterase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95551-2." [PRO:DNx, UniProtKB:O95551]
comment: Category=organism-sequence.
synonym: "hTDP2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95551-2
is_a: PR:O95551 ! tyrosyl-DNA phosphodiesterase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O95551-3
name: tyrosyl-DNA phosphodiesterase 2 isoform h3 (human)
def: "A tyrosyl-DNA phosphodiesterase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95551-3." [PRO:DNx, UniProtKB:O95551]
comment: Category=organism-sequence.
synonym: "hTDP2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O95551-3
is_a: PR:O95551 ! tyrosyl-DNA phosphodiesterase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9XWG3
name: 5'-tyrosyl-DNA phosphodiesterase (worm)
def: "A tyrosyl-DNA phosphodiesterase 2 that is encoded in the genome of worm." [OMA:Q9XWG3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Y63D3A.4" RELATED Gene-based [UniProtKB:Q9XWG3]
synonym: "TDP2 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "5'-Tyr-DNA phosphodiesterase (worm)" EXACT [UniProtKB:Q9XWG3]
xref: UniProtKB:Q9XWG3
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000016802 ! tyrosyl-DNA phosphodiesterase 2
relationship: has_gene_template WormBase:WBGene00013405 ! Y63D3A.4 (worm)