[Term]
id: PR:000021724
name: tripeptidyl-peptidase 1, signal peptide removed form
def: "A tripeptidyl-peptidase 1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "TPP1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000021725
name: tripeptidyl-peptidase 1 proteolytic cleavage product
def: "A tripeptidyl-peptidase 1 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "TPP1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1

[Term]
id: PR:Q9EQV6-1
name: tripeptidyl-peptidase 1 isoform 1 (rat)
def: "A tripeptidyl-peptidase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rTPP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9EQV6-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000037999 ! tripeptidyl-peptidase 1 isoform 1

[Term]
id: PR:000059521
name: tripeptidyl-peptidase 1 N-glycosylated 8 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-443 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G41247ZX." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G41247ZX" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G41247ZX ! G41247ZX
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O14773-1
name: tripeptidyl-peptidase 1 isoform 1 (human)
def: "A tripeptidyl-peptidase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hTPP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14773-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037999 ! tripeptidyl-peptidase 1 isoform 1

[Term]
id: PR:Q55CT0
name: tripeptidyl-peptidase 1 (Dictyostelium discoideum)
def: "A tripeptidyl-peptidase 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55CT0, PRO:DNx]
comment: Category=organism-gene.
synonym: "tpp1" RELATED Gene-based [UniProtKB:Q55CT0]
synonym: "Dicty-TPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0269914" RELATED Gene-based [UniProtKB:Q55CT0]
synonym: "TPP-1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55CT0]
synonym: "TPP-I (Dictyostelium discoideum)" EXACT [UniProtKB:Q55CT0]
synonym: "tripeptidyl-peptidase I (Dictyostelium discoideum)" EXACT [UniProtKB:Q55CT0]
synonym: "tripeptidyl aminopeptidase (Dictyostelium discoideum)" EXACT [UniProtKB:Q55CT0]
xref: UniProtKB:Q55CT0
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
relationship: has_gene_template dictyBase:DDB_G0269914 ! tpp1 (Dictyostelium discoideum)

[Term]
id: PR:Q9EQV6
name: tripeptidyl-peptidase 1 (rat)
def: "A tripeptidyl-peptidase 1 that is encoded in the genome of rat." [PANTHER:PTHR14218:SF5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cln2" RELATED Gene-based [UniProtKB:Q9EQV6]
synonym: "Tpp1" RELATED Gene-based [UniProtKB:Q9EQV6]
synonym: "rTPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "TPP-1 (rat)" EXACT [UniProtKB:Q9EQV6]
synonym: "TPP-I (rat)" EXACT [UniProtKB:Q9EQV6]
synonym: "tripeptidyl-peptidase I (rat)" EXACT [UniProtKB:Q9EQV6]
synonym: "tripeptidyl aminopeptidase (rat)" RELATED [UniProtKB:Q9EQV6]
xref: UniProtKB:Q9EQV6
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
relationship: has_gene_template RGD:621296 ! Tpp1 (rat)

[Term]
id: PR:O89023
name: tripeptidyl-peptidase 1 (mouse)
def: "A tripeptidyl-peptidase 1 that is encoded in the genome of mouse." [OMA:O89023, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cln2" RELATED Gene-based [UniProtKB:O89023]
synonym: "Tpp1" RELATED Gene-based [UniProtKB:O89023]
synonym: "mTPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "LPIC (mouse)" EXACT [UniProtKB:O89023]
synonym: "TPP-1 (mouse)" EXACT [UniProtKB:O89023]
synonym: "TPP-I (mouse)" EXACT [UniProtKB:O89023]
synonym: "tripeptidyl-peptidase I (mouse)" EXACT [UniProtKB:O89023]
synonym: "tripeptidyl aminopeptidase (mouse)" RELATED [UniProtKB:O89023]
synonym: "lysosomal pepstatin-insensitive protease (mouse)" EXACT [UniProtKB:O89023]
xref: UniProtKB:O89023
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
relationship: has_gene_template MGI:1336194 ! Tpp1 (mouse)

[Term]
id: PR:F8W2M8
name: tripeptidyl-peptidase 1 (zebrafish)
def: "A tripeptidyl-peptidase 1 that is encoded in the genome of zebrafish." [OMA:F8W2M8, PANTHER:PTHR14218:SF5, PRO:DNx]
comment: Category=organism-gene.
synonym: "tpp1" RELATED Gene-based [UniProtKB:F8W2M8]
synonym: "z-TPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "TPP-1 (zebrafish)" EXACT [UniProtKB:F8W2M8]
synonym: "TPP-I (zebrafish)" EXACT [UniProtKB:F8W2M8]
synonym: "tripeptidyl-peptidase I (zebrafish)" EXACT [UniProtKB:F8W2M8]
synonym: "tripeptidyl aminopeptidase (zebrafish)" EXACT [UniProtKB:F8W2M8]
xref: UniProtKB:F8W2M8
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
relationship: has_gene_template ZFIN:ZDB-GENE-030131-6654 ! tpp1 (zebrafish)

[Term]
id: PR:O14773
name: tripeptidyl-peptidase 1 (human)
def: "A tripeptidyl-peptidase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14773]
comment: Category=organism-gene.
synonym: "CLN2" RELATED Gene-based [UniProtKB:O14773]
synonym: "GIG1" RELATED Gene-based [UniProtKB:O14773]
synonym: "TPP1" RELATED Gene-based [UniProtKB:O14773]
synonym: "hTPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "LPIC (human)" EXACT [UniProtKB:O14773]
synonym: "TPP-1 (human)" EXACT [UniProtKB:O14773]
synonym: "TPP-I (human)" EXACT [UniProtKB:O14773]
synonym: "UNQ267/PRO304" RELATED Gene-based [UniProtKB:O14773]
synonym: "tripeptidyl-peptidase I (human)" EXACT [UniProtKB:O14773]
synonym: "tripeptidyl aminopeptidase (human)" BROAD [UniProtKB:O14773]
synonym: "cell growth-inhibiting gene 1 protein (human)" EXACT [UniProtKB:O14773]
synonym: "lysosomal pepstatin-insensitive protease (human)" EXACT [UniProtKB:O14773]
xref: UniProtKB:O14773
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
relationship: has_gene_template HGNC:2073 ! TPP1 (human)

[Term]
id: PR:000059520
name: tripeptidyl-peptidase 1 N-glycosylated 7 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-443 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan composition is represented by GlyTouCan:G28681TP. Example: UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G28681TP." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G28681TP" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G28681TP ! G28681TP
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000059518
name: tripeptidyl-peptidase 1 N-glycosylated 5 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-443 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G02815KT." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G02815KT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G02815KT ! G02815KT
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000059519
name: tripeptidyl-peptidase 1 N-glycosylated 6 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-443 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan composition is represented by GlyTouCan:G20956ZV. Example: UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G20956ZV." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-443, MOD:00160~GNO:G20956ZV" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G20956ZV ! G20956ZV
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000050704
name: tripeptidyl-peptidase 1 N-glycosylated 1 (human)
def: "A tripeptidyl-peptidase 1 (human) that has been N-glycosylated at the residue equivalent to Asn-210 of the amino acid sequence represented by UniProtKB:O14773-1, in which the glycan composition is represented by GlyTouCan:G80735OA. Example: UniProtKB:O14773-1, Asn-210, MOD:00160~GNO:G80735OA." [GlyGen:O14773-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTPP1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14773-1, Asn-210, MOD:00160~GNO:G80735OA" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O14773 ! tripeptidyl-peptidase 1 (human)
relationship: has_part GNO:G80735OA ! G80735OA
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000059515
name: tripeptidyl-peptidase 1 N-glycosylated 2 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-210 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan composition is represented by GlyTouCan:G31852PQ. Example: UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~GNO:G31852PQ." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~GNO:G31852PQ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G31852PQ ! G31852PQ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000059514
name: tripeptidyl-peptidase 1 N-glycosylated 1 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-210 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan structure is represented by GlyTouCan:G09775CH. Example: UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~GNO:G09775CH." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~GNO:G09775CH" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~UniCarbKB:7896" NARROW [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G09775CH ! G09775CH
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000037999
name: tripeptidyl-peptidase 1 isoform 1
def: "A tripeptidyl-peptidase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14773-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "TPP1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016585 ! tripeptidyl-peptidase 1

[Term]
id: PR:000059516
name: tripeptidyl-peptidase 1 N-glycosylated 3 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-210 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan structure is represented by GlyTouCan:G37135JQ. Example: UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~GNO:G37135JQ." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~GNO:G37135JQ" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-210, MOD:00160~UniCarbKB:3869" NARROW [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G37135JQ ! G37135JQ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000059517
name: tripeptidyl-peptidase 1 N-glycosylated 4 (rat)
def: "A tripeptidyl-peptidase 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-222 of the amino acid sequence represented by UniProtKB:Q9EQV6-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:Q9EQV6-1, Asn-222, MOD:00160~GNO:G02815KT." [GlyGen:Q9EQV6-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rTPP1/NGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9EQV6-1, Asn-222, MOD:00160~GNO:G02815KT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9EQV6 ! tripeptidyl-peptidase 1 (rat)
relationship: has_part GNO:G02815KT ! G02815KT
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O14773-2
name: tripeptidyl-peptidase 1 isoform h2 (human)
def: "A tripeptidyl-peptidase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14773-2." [PRO:DNx, UniProtKB:O14773]
comment: Category=organism-sequence.
synonym: "hTPP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14773-2
is_a: PR:O14773 ! tripeptidyl-peptidase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016585
name: tripeptidyl-peptidase 1
def: "A protein that is a translation product of the human TPP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CLN2" RELATED Gene-based []
synonym: "GIG1" RELATED Gene-based []
synonym: "LPIC" EXACT []
synonym: "TPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "TPP-1" EXACT []
synonym: "TPP-I" EXACT []
synonym: "UNQ267/PRO304" RELATED Gene-based []
synonym: "tripeptidyl-peptidase I" EXACT []
synonym: "tripeptidyl aminopeptidase" BROAD [PRO:DNx]
synonym: "cell growth-inhibiting gene 1 protein" EXACT []
synonym: "lysosomal pepstatin-insensitive protease" EXACT []
is_a: PR:000000001 ! protein