[Term] id: PR:000021673 name: metalloproteinase inhibitor 2, signal peptide removed form def: "A metalloproteinase inhibitor 2 that has had the signal peptide removed." [PRO:DNx] comment: Category=modification. synonym: "TIMP2/SigPep-" EXACT PRO-short-label [PRO:DNx] intersection_of: PR:000016353 ! metalloproteinase inhibitor 2 intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:P16035 name: metalloproteinase inhibitor 2 (human) def: "A metalloproteinase inhibitor 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P16035] comment: Category=organism-gene. synonym: "TIMP2" RELATED Gene-based [UniProtKB:P16035] synonym: "hTIMP2" EXACT PRO-short-label [PRO:DNx] synonym: "TIMP-2 (human)" EXACT [UniProtKB:P16035] synonym: "CSC-21K (human)" EXACT [UniProtKB:P16035] synonym: "tissue inhibitor of metalloproteinases 2 (human)" EXACT [UniProtKB:P16035] xref: UniProtKB:P16035 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000016353 ! metalloproteinase inhibitor 2 relationship: has_gene_template HGNC:11821 ! TIMP2 (human) [Term] id: PR:Q21265 name: putative metalloproteinase inhibitor tag-225 (worm) def: "A metalloproteinase inhibitor 2 that is encoded in the genome of worm." [OMA:Q21265, PRO:DNx] comment: Category=organism-gene. synonym: "cri-2" RELATED Gene-based [UniProtKB:Q21265] synonym: "tag-225" RELATED Gene-based [UniProtKB:Q21265] synonym: "K07C11.5" RELATED Gene-based [UniProtKB:Q21265] synonym: "TIMP2 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "TIMP-like protein (worm)" EXACT [UniProtKB:Q21265] xref: UniProtKB:Q21265 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000016353 ! metalloproteinase inhibitor 2 relationship: has_gene_template WormBase:WBGene00019478 ! cri-2 (worm) [Term] id: PR:000016353 name: metalloproteinase inhibitor 2 def: "A protein that is a translation product of the human TIMP2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "TIMP2" EXACT PRO-short-label [PRO:DNx] synonym: "TIMP-2" EXACT [] synonym: "CSC-21K" EXACT [] synonym: "tissue inhibitor of metalloproteinases 2" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000049458 name: metalloproteinase inhibitor 2, signal peptide removed form (human) def: "A metalloproteinase inhibitor 2 (human) that has had the signal peptide removed. UniProtKB:P16035, 27-220." [PRO:DNx, Reactome:R-HSA-1454879] comment: Category=organism-modification. synonym: "PRO_0000034335" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hTIMP2/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P16035, 27-220" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1454879 "PR:000049458 located_in GO:0005576" xref: Reactome:R-HSA-6799625 "PR:000049458 located_in GO:0035580" xref: Reactome:R-HSA-6800881 "PR:000049458 located_in GO:1904724" xref: Reactome:R-HSA-6800944 "PR:000049458 located_in GO:1904813" intersection_of: PR:P16035 ! metalloproteinase inhibitor 2 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O42146 name: metalloproteinase inhibitor 2 (chicken) def: "A metalloproteinase inhibitor 2 that is encoded in the genome of chicken." [OMA:O42146, PRO:DNx] comment: Category=organism-gene. synonym: "TIMP2" RELATED Gene-based [UniProtKB:O42146] synonym: "chick-TIMP2" EXACT PRO-short-label [PRO:DNx] synonym: "TIMP-2 (chicken)" EXACT [UniProtKB:O42146] synonym: "tissue inhibitor of metalloproteinases 2 (chicken)" EXACT [UniProtKB:O42146] xref: UniProtKB:O42146 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000016353 ! metalloproteinase inhibitor 2 relationship: has_gene_template NCBIGene:374178 ! TIMP2 (chicken) [Term] id: PR:P30121-1 name: metalloproteinase inhibitor 2 isoform 1 (rat) def: "A metalloproteinase inhibitor 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rTIMP2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P30121-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000038944 ! metalloproteinase inhibitor 2 isoform 1 [Term] id: PR:P30121 name: metalloproteinase inhibitor 2 (rat) def: "A metalloproteinase inhibitor 2 that is encoded in the genome of rat." [OMA:P30121, PANTHER:PTHR11844:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "Timp2" RELATED Gene-based [UniProtKB:P30121] synonym: "Timp-2" RELATED Gene-based [UniProtKB:P30121] synonym: "rTIMP2" EXACT PRO-short-label [PRO:DNx] synonym: "TIMP-2 (rat)" EXACT [UniProtKB:P30121] synonym: "tissue inhibitor of metalloproteinases 2 (rat)" EXACT [UniProtKB:P30121] xref: UniProtKB:P30121 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000016353 ! metalloproteinase inhibitor 2 relationship: has_gene_template RGD:61312 ! Timp2 (rat) [Term] id: PR:000038944 name: metalloproteinase inhibitor 2 isoform 1 def: "A metalloproteinase inhibitor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16035-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "TIMP2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000016353 ! metalloproteinase inhibitor 2 [Term] id: PR:P25785 name: metalloproteinase inhibitor 2 (mouse) def: "A metalloproteinase inhibitor 2 that is encoded in the genome of mouse." [OMA:P25785, PRO:DNx] comment: Category=organism-gene. synonym: "Timp2" RELATED Gene-based [UniProtKB:P25785] synonym: "Timp-2" RELATED Gene-based [UniProtKB:P25785] synonym: "mTIMP2" EXACT PRO-short-label [PRO:DNx] synonym: "TIMP-2 (mouse)" EXACT [UniProtKB:P25785] synonym: "tissue inhibitor of metalloproteinases 2 (mouse)" EXACT [UniProtKB:P25785] xref: UniProtKB:P25785 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000016353 ! metalloproteinase inhibitor 2 relationship: has_gene_template MGI:98753 ! Timp2 (mouse) [Term] id: PR:P16035-1 name: metalloproteinase inhibitor 2 isoform 1 (human) def: "A metalloproteinase inhibitor 2 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hTIMP2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P16035-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000038944 ! metalloproteinase inhibitor 2 isoform 1