[Term] id: PR:000015876 name: nesprin-2 def: "A protein that is a translation product of the human SYNE2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "NUA" RELATED Gene-based [] synonym: "KASH2" EXACT [] synonym: "SYNE2" EXACT PRO-short-label [PRO:DNx] synonym: "Syne-2" EXACT [] synonym: "KIAA1011" RELATED Gene-based [] synonym: "protein NUANCE" EXACT [] synonym: "KASH domain-containing protein 2" EXACT [] synonym: "synaptic nuclear envelope protein 2" EXACT [] synonym: "nuclear envelope spectrin repeat protein 2" EXACT [] synonym: "nucleus and actin connecting element protein" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q8WXH0-10 name: nesprin-2 isoform h10 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-10." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h10" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform beta2 (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-10 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026490 name: nesprin-2 isoform 5 def: "A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-5 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "SYNE2/iso:5" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015876 ! nesprin-2 [Term] id: PR:M9MRD1 name: muscle-specific protein 300 kDa (fruit fly) def: "A nesprin-2 that is encoded in the genome of fruit fly." [OMA:M9MRD1, PRO:DNx] comment: Category=organism-gene. synonym: "Msp300" RELATED Gene-based [UniProtKB:M9MRD1] synonym: "CG42768" RELATED Gene-based [UniProtKB:M9MRD1] synonym: "fly-SYNE2" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-like protein Msp300 (fruit fly)" EXACT [UniProtKB:M9MRD1] xref: UniProtKB:M9MRD1 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000015876 ! nesprin-2 relationship: has_gene_template FlyBase:FBgn0261836 ! Msp300 (fruit fly) [Term] id: PR:Q9N4M4 name: nuclear anchorage protein 1 (worm) def: "A nesprin-2 that is encoded in the genome of worm." [OMA:Q9N4M4, PRO:DNx] comment: Category=organism-gene. synonym: "anc-1" RELATED Gene-based [UniProtKB:Q9N4M4] synonym: "ZK973.6" RELATED Gene-based [UniProtKB:Q9N4M4] synonym: "SYNE2 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin homolog (worm)" EXACT [UniProtKB:Q9N4M4] synonym: "anchorage 1 protein (worm)" EXACT [UniProtKB:Q9N4M4] xref: UniProtKB:Q9N4M4 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000015876 ! nesprin-2 relationship: has_gene_template WormBase:WBGene00000140 ! anc-1 (worm) [Term] id: PR:Q6ZWQ0-3 name: nesprin-2 isoform m3 (mouse) def: "A nesprin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZWQ0-3." [PRO:DNx, UniProtKB:Q6ZWQ0] comment: Category=organism-sequence. synonym: "mSYNE2/iso:m3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6ZWQ0-3 is_a: PR:Q6ZWQ0 ! nesprin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q6ZWQ0-2 name: nesprin-2 isoform m2 (mouse) def: "A nesprin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZWQ0-2." [PRO:DNx, UniProtKB:Q6ZWQ0] comment: Category=organism-sequence. synonym: "mSYNE2/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6ZWQ0-2 is_a: PR:Q6ZWQ0 ! nesprin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q6ZWQ0-1 name: nesprin-2 isoform m1 (mouse) def: "A nesprin-2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZWQ0-1." [PRO:DNx, UniProtKB:Q6ZWQ0] comment: Category=organism-sequence. synonym: "mSYNE2/iso:m1" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform NUANCE (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "nesprin-2 isoform Nesp2G (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "nesprin-2 isoform Nesprin-2 Giant (mouse)" EXACT [UniProtKB:Q6ZWQ0] xref: UniProtKB:Q6ZWQ0-1 is_a: PR:Q6ZWQ0 ! nesprin-2 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q8WXH0-12 name: nesprin-2 isoform h12 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-12." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h12" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform FLJ55476 (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-12 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026488 name: nesprin-2 isoform 4 def: "A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-4 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "SYNE2/iso:4" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015876 ! nesprin-2 [Term] id: PR:000026484 name: nesprin-2 isoform 2 def: "A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-2 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "SYNE2/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015876 ! nesprin-2 [Term] id: PR:Q8WXH0-11 name: nesprin-2 isoform h11 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-11." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h11" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform FLJ56122 (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-11 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026486 name: nesprin-2 isoform 3 def: "A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-3 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "SYNE2/iso:3" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015876 ! nesprin-2 [Term] id: PR:Q8WXH0-13 name: nesprin-2 isoform h13 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-13." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h13" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform JAM28 (human)" EXACT [UniProtKB:Q8WXH0] synonym: "nesprin-2 isoform epsilon1 (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-13 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000026482 name: nesprin-2 isoform 1 def: "A nesprin-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-1 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "SYNE2/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015876 ! nesprin-2 [Term] id: PR:Q8WXH0 name: nesprin-2 (human) def: "A nesprin-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-gene. synonym: "NUA" RELATED Gene-based [UniProtKB:Q8WXH0] synonym: "SYNE2" RELATED Gene-based [UniProtKB:Q8WXH0] synonym: "hSYNE2" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1011" RELATED Gene-based [UniProtKB:Q8WXH0] synonym: "KASH2 (human)" EXACT [UniProtKB:Q8WXH0] synonym: "Syne-2 (human)" EXACT [UniProtKB:Q8WXH0] synonym: "protein NUANCE (human)" EXACT [UniProtKB:Q8WXH0] synonym: "KASH domain-containing protein 2 (human)" EXACT [UniProtKB:Q8WXH0] synonym: "synaptic nuclear envelope protein 2 (human)" EXACT [UniProtKB:Q8WXH0] synonym: "nuclear envelope spectrin repeat protein 2 (human)" EXACT [UniProtKB:Q8WXH0] synonym: "nucleus and actin connecting element protein (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0 xref: Reactome:R-HSA-912404 "PR:Q8WXH0 located_in GO:0005635" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000015876 ! nesprin-2 relationship: has_gene_template HGNC:17084 ! SYNE2 (human) [Term] id: PR:Q6ZWQ0 name: nesprin-2 (mouse) def: "A nesprin-2 that is encoded in the genome of mouse." [OMA:Q6ZWQ0, PRO:DNx] comment: Category=organism-gene. synonym: "Syne2" RELATED Gene-based [UniProtKB:Q6ZWQ0] synonym: "mSYNE2" EXACT PRO-short-label [PRO:DNx] synonym: "KASH2 (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "Syne-2 (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "protein NUANCE (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "KASH domain-containing protein 2 (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "synaptic nuclear envelope protein 2 (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "nuclear envelope spectrin repeat protein 2 (mouse)" EXACT [UniProtKB:Q6ZWQ0] synonym: "nucleus and actin connecting element protein (mouse)" EXACT [UniProtKB:Q6ZWQ0] xref: UniProtKB:Q6ZWQ0 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000015876 ! nesprin-2 relationship: has_gene_template MGI:2449316 ! Syne2 (mouse) [Term] id: PR:Q8WXH0-6 name: nesprin-2 isoform h6 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-6." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h6" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform alpha2 (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-6 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8WXH0-7 name: nesprin-2 isoform h7 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-7." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h7" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform Gamma (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-7 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8WXH0-4 name: nesprin-2 isoform 4 (human) def: "A nesprin-2 isoform 4 that is encoded in the genome of human." [PMID:19933576] comment: Category=organism-sequence. synonym: "hSYNE2/iso:4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8WXH0-4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026488 ! nesprin-2 isoform 4 [Term] id: PR:Q8WXH0-5 name: nesprin-2 isoform 5 (human) def: "A nesprin-2 isoform 5 that is encoded in the genome of human." [PMID:19933576] comment: Category=organism-sequence. synonym: "hSYNE2/iso:5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8WXH0-5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026490 ! nesprin-2 isoform 5 [Term] id: PR:Q8WXH0-2 name: nesprin-2 isoform 2 (human) def: "A nesprin-2 isoform 2 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hSYNE2/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8WXH0-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026484 ! nesprin-2 isoform 2 [Term] id: PR:Q8WXH0-3 name: nesprin-2 isoform 3 (human) def: "A nesprin-2 isoform 3 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hSYNE2/iso:3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8WXH0-3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026486 ! nesprin-2 isoform 3 [Term] id: PR:Q8WXH0-1 name: nesprin-2 isoform 1 (human) def: "A nesprin-2 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hSYNE2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8WXH0-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000026482 ! nesprin-2 isoform 1 [Term] id: PR:Q8WXH0-8 name: nesprin-2 isoform h8 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-8." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h8" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform p32CH (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-8 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q8WXH0-9 name: nesprin-2 isoform h9 (human) def: "A nesprin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WXH0-9." [PRO:DNx, UniProtKB:Q8WXH0] comment: Category=organism-sequence. synonym: "hSYNE2/iso:h9" EXACT PRO-short-label [PRO:DNx] synonym: "nesprin-2 isoform NUANCE-N-33 (human)" EXACT [UniProtKB:Q8WXH0] xref: UniProtKB:Q8WXH0-9 is_a: PR:Q8WXH0 ! nesprin-2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens