[Term] id: PR:O43295-1 name: SLIT-ROBO Rho GTPase-activating protein 3 isoform h1 (human) def: "A SLIT-ROBO Rho GTPase-activating protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43295-1." [PRO:DNx, UniProtKB:O43295] comment: Category=organism-sequence. synonym: "hSRGAP3/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "SLIT-ROBO Rho GTPase-activating protein 3 isoform MEGAPa (human)" EXACT [UniProtKB:O43295] synonym: "SLIT-ROBO Rho GTPase-activating protein 3 isoform srGAP3a (human)" EXACT [UniProtKB:O43295] xref: UniProtKB:O43295-1 is_a: PR:O43295 ! SLIT-ROBO Rho GTPase-activating protein 3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O43295-2 name: SLIT-ROBO Rho GTPase-activating protein 3 isoform h2 (human) def: "A SLIT-ROBO Rho GTPase-activating protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43295-2." [PRO:DNx, UniProtKB:O43295] comment: Category=organism-sequence. synonym: "hSRGAP3/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "SLIT-ROBO Rho GTPase-activating protein 3 isoform MEGAPb (human)" EXACT [UniProtKB:O43295] synonym: "SLIT-ROBO Rho GTPase-activating protein 3 isoform srGAP3b (human)" EXACT [UniProtKB:O43295] xref: UniProtKB:O43295-2 is_a: PR:O43295 ! SLIT-ROBO Rho GTPase-activating protein 3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O43295-3 name: SLIT-ROBO Rho GTPase-activating protein 3 isoform h3 (human) def: "A SLIT-ROBO Rho GTPase-activating protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43295-3." [PRO:DNx, UniProtKB:O43295] comment: Category=organism-sequence. synonym: "hSRGAP3/iso:h3" EXACT PRO-short-label [PRO:DNx] synonym: "SLIT-ROBO Rho GTPase-activating protein 3 isoform MEGAPc (human)" EXACT [UniProtKB:O43295] synonym: "SLIT-ROBO Rho GTPase-activating protein 3 isoform srGAP3c (human)" EXACT [UniProtKB:O43295] xref: UniProtKB:O43295-3 is_a: PR:O43295 ! SLIT-ROBO Rho GTPase-activating protein 3 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000015617 name: SLIT-ROBO Rho GTPase-activating protein 3 def: "A protein that is a translation product of the human SRGAP3 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "WRP" EXACT [] synonym: "MEGAP" RELATED Gene-based [] synonym: "SRGAP3" EXACT PRO-short-label [PRO:DNx] synonym: "srGAP2" RELATED [] synonym: "srGAP3" EXACT [] synonym: "ARHGAP14" RELATED Gene-based [] synonym: "KIAA0411" RELATED Gene-based [] synonym: "KIAA1156" RELATED Gene-based [] synonym: "mental disorder-associated GAP" EXACT [] synonym: "Rho GTPase-activating protein 14" EXACT [] synonym: "WAVE-associated Rac GTPase-activating protein" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000030159 name: SLIT-ROBO Rho GTPase-activating protein 3 phosphorylated 1 (mouse) def: "A SLIT-ROBO Rho GTPase-activating protein 3 phosphorylated 1 in mouse. UniProtKB:Q812A2, Ser-1070, MOD:00046." [PMID:17114649, PRO:HJD] comment: Category=organism-modification. Note: Large-scale experiment. synonym: "mSRGAP3/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q812A2, Ser-1070, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000030158 ! SLIT-ROBO Rho GTPase-activating protein 3 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000030158 name: SLIT-ROBO Rho GTPase-activating protein 3 phosphorylated 1 def: "A SLIT-ROBO Rho GTPase-activating protein 3 that has been phosphorylated at the position equivalent to Ser-1070 of the amino acid sequence represented by UniProtKB:Q812A2. Example: UniProtKB:Q812A2, Ser-1070, MOD:00046." [PMID:17114649, PRO:HJD] comment: Category=modification. Note: Large-scale experiment. synonym: "SRGAP3/Phos:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015617 ! SLIT-ROBO Rho GTPase-activating protein 3 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:Q812A2 name: SLIT-ROBO Rho GTPase-activating protein 3 (mouse) def: "A SLIT-ROBO Rho GTPase-activating protein 3 that is encoded in the genome of mouse." [OMA:Q812A2, PRO:DNx] comment: Category=organism-gene. synonym: "Srgap2" RELATED Gene-based [UniProtKB:Q812A2] synonym: "Srgap3" RELATED Gene-based [UniProtKB:Q812A2] synonym: "mSRGAP3" EXACT PRO-short-label [PRO:DNx] synonym: "Arhgap14" RELATED Gene-based [UniProtKB:Q812A2] synonym: "Kiaa0411" RELATED Gene-based [UniProtKB:Q812A2] synonym: "WRP (mouse)" EXACT [UniProtKB:Q812A2] synonym: "srGAP3 (mouse)" EXACT [UniProtKB:Q812A2] synonym: "Rho GTPase-activating protein 14 (mouse)" EXACT [UniProtKB:Q812A2] synonym: "WAVE-associated Rac GTPase-activating protein (mouse)" EXACT [UniProtKB:Q812A2] xref: UniProtKB:Q812A2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000015617 ! SLIT-ROBO Rho GTPase-activating protein 3 relationship: has_gene_template MGI:2152938 ! Srgap3 (mouse) [Term] id: PR:O43295 name: SLIT-ROBO Rho GTPase-activating protein 3 (human) def: "A SLIT-ROBO Rho GTPase-activating protein 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43295] comment: Category=organism-gene. synonym: "MEGAP" RELATED Gene-based [UniProtKB:O43295] synonym: "SRGAP2" RELATED Gene-based [UniProtKB:O43295] synonym: "SRGAP3" RELATED Gene-based [UniProtKB:O43295] synonym: "hSRGAP3" EXACT PRO-short-label [PRO:DNx] synonym: "ARHGAP14" RELATED Gene-based [UniProtKB:O43295] synonym: "KIAA0411" RELATED Gene-based [UniProtKB:O43295] synonym: "KIAA1156" RELATED Gene-based [UniProtKB:O43295] synonym: "WRP (human)" EXACT [UniProtKB:O43295] synonym: "srGAP3 (human)" EXACT [UniProtKB:O43295] synonym: "mental disorder-associated GAP (human)" EXACT [UniProtKB:O43295] synonym: "Rho GTPase-activating protein 14 (human)" EXACT [UniProtKB:O43295] synonym: "WAVE-associated Rac GTPase-activating protein (human)" EXACT [UniProtKB:O43295] xref: Reactome:R-HSA-428463 "PR:O43295 located_in GO:0005829" xref: UniProtKB:O43295 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000015617 ! SLIT-ROBO Rho GTPase-activating protein 3 relationship: has_gene_template HGNC:19744 ! SRGAP3 (human)