[Term]
id: PR:Q3U1N2-1
name: sterol regulatory element-binding protein 2 isoform m1 (mouse)
def: "A sterol regulatory element-binding protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3U1N2-1." [PRO:DNx, UniProtKB:Q3U1N2]
comment: Category=organism-sequence.
synonym: "mSREBF2/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3U1N2-1
is_a: PR:Q3U1N2 ! sterol regulatory element-binding protein 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:A3KNA7
name: sterol regulatory element-binding protein 2 (zebrafish)
def: "A sterol regulatory element-binding protein 2 that is encoded in the genome of zebrafish." [OMA:A3KNA7, PANTHER:PTHR12565:SF6, PRO:DNx]
comment: Category=organism-gene.
synonym: "SREBP2" RELATED Gene-based [UniProtKB:A3KNA7]
synonym: "srebf2" RELATED Gene-based [UniProtKB:A3KNA7]
synonym: "z-SREBF2" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:158371" RELATED Gene-based [UniProtKB:A3KNA7]
synonym: "SREBP-2 (zebrafish)" EXACT [UniProtKB:A3KNA7]
synonym: "sterol regulatory element-binding transcription factor 2 (zebrafish)" EXACT [UniProtKB:A3KNA7]
xref: UniProtKB:A3KNA7
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000015612 ! sterol regulatory element-binding protein 2
relationship: has_gene_template ZFIN:ZDB-GENE-070410-8 ! srebf2 (zebrafish)

[Term]
id: PR:Q3T1I5
name: sterol regulatory element-binding protein 2 (rat)
def: "A sterol regulatory element-binding protein 2 that is encoded in the genome of rat." [OMA:Q3T1I5, PANTHER:PTHR12565:SF6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Srebf2" RELATED Gene-based [UniProtKB:Q3T1I5]
synonym: "rSREBF2" EXACT PRO-short-label [PRO:DNx]
synonym: "SREBP-2 (rat)" EXACT [UniProtKB:Q3T1I5]
synonym: "sterol regulatory element-binding transcription factor 2 (rat)" EXACT [UniProtKB:Q3T1I5]
xref: UniProtKB:Q3T1I5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000015612 ! sterol regulatory element-binding protein 2
relationship: has_gene_template RGD:1307751 ! Srebf2 (rat)

[Term]
id: PR:Q3U1N2-2
name: sterol regulatory element-binding protein 2 isoform m2 (mouse)
def: "A sterol regulatory element-binding protein 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3U1N2-2." [PRO:DNx, UniProtKB:Q3U1N2]
comment: Category=organism-sequence.
synonym: "mSREBF2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3U1N2-2
is_a: PR:Q3U1N2 ! sterol regulatory element-binding protein 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q12772-1
name: sterol regulatory element-binding protein 2 isoform h1 (human)
def: "A sterol regulatory element-binding protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12772-1." [PRO:DNx, UniProtKB:Q12772]
comment: Category=organism-sequence.
synonym: "hSREBF2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12772-1
is_a: PR:Q12772 ! sterol regulatory element-binding protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12772-2
name: sterol regulatory element-binding protein 2 isoform h2 (human)
def: "A sterol regulatory element-binding protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12772-2." [PRO:DNx, UniProtKB:Q12772]
comment: Category=organism-sequence.
synonym: "hSREBF2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12772-2
is_a: PR:Q12772 ! sterol regulatory element-binding protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q3U1N2
name: sterol regulatory element-binding protein 2 (mouse)
def: "A sterol regulatory element-binding protein 2 that is encoded in the genome of mouse." [OMA:Q3U1N2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Srebf2" RELATED Gene-based [UniProtKB:Q3U1N2]
synonym: "Srebp2" RELATED Gene-based [UniProtKB:Q3U1N2]
synonym: "mSREBF2" EXACT PRO-short-label [PRO:DNx]
synonym: "SREBP-2 (mouse)" EXACT [UniProtKB:Q3U1N2]
synonym: "sterol regulatory element-binding transcription factor 2 (mouse)" EXACT [UniProtKB:Q3U1N2]
xref: UniProtKB:Q3U1N2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000015612 ! sterol regulatory element-binding protein 2
relationship: has_gene_template MGI:107585 ! Srebf2 (mouse)

[Term]
id: PR:Q12772
name: sterol regulatory element-binding protein 2 (human)
def: "A sterol regulatory element-binding protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q12772]
comment: Category=organism-gene.
synonym: "BHLHD2" RELATED Gene-based [UniProtKB:Q12772]
synonym: "SREBF2" RELATED Gene-based [UniProtKB:Q12772]
synonym: "SREBP2" RELATED Gene-based [UniProtKB:Q12772]
synonym: "hSREBF2" EXACT PRO-short-label [PRO:DNx]
synonym: "SREBP-2 (human)" EXACT [UniProtKB:Q12772]
synonym: "class D basic helix-loop-helix protein 2 (human)" EXACT [UniProtKB:Q12772]
synonym: "sterol regulatory element-binding transcription factor 2 (human)" EXACT [UniProtKB:Q12772]
xref: UniProtKB:Q12772
xref: Reactome:R-HSA-1655733 "PR:Q12772 located_in GO:0005789"
xref: Reactome:R-HSA-1655747 "PR:Q12772 located_in GO:0000139"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015612 ! sterol regulatory element-binding protein 2
relationship: has_gene_template HGNC:11290 ! SREBF2 (human)

[Term]
id: PR:000021564
name: sterol regulatory element-binding protein 2 proteolytic cleavage product
def: "A sterol regulatory element-binding protein 2 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "SREBF2/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000015612 ! sterol regulatory element-binding protein 2

[Term]
id: PR:000015612
name: sterol regulatory element-binding protein 2
def: "A sterol regulatory element-binding protein that is a translation product of the human SREBF2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "BHLHD2" RELATED Gene-based []
synonym: "SREBF2" EXACT PRO-short-label [PRO:DNx]
synonym: "SREBP2" RELATED Gene-based []
synonym: "bHLHd2" EXACT []
synonym: "SREBP-2" EXACT []
synonym: "class D basic helix-loop-helix protein 2" EXACT []
synonym: "sterol regulatory element-binding transcription factor 2" EXACT []
is_a: PR:000028988 ! sterol regulatory element-binding protein