[Term] id: PR:O15269-2 name: serine palmitoyltransferase 1 isoform h2 (human) def: "A serine palmitoyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15269-2." [PRO:DNx, UniProtKB:O15269] comment: Category=organism-sequence. synonym: "hSPTLC1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O15269-2 is_a: PR:O15269 ! serine palmitoyltransferase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000015596 name: serine palmitoyltransferase 1 def: "A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "LCB1" RELATED Gene-based [] synonym: "SPT1" EXACT [] synonym: "LCB 1" EXACT [] synonym: "SPT 1" EXACT [] synonym: "SPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "serine-palmitoyl-CoA transferase 1" EXACT [] synonym: "long chain base biosynthesis protein 1" EXACT [] xref: IUPHARobj:2509 is_a: PR:000026126 ! eukaryotic serine palmitoyltransferase [Term] id: PR:O15269-1 name: serine palmitoyltransferase 1 isoform 1 (human) def: "A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of human." [PRO:HJD] comment: Category=organism-sequence. synonym: "hSPTLC1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O15269-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000022019 ! serine palmitoyltransferase 1 isoform 1 [Term] id: PR:Q55FL5 name: serine palmitoyltransferase 1 (Dictyostelium discoideum) def: "A serine palmitoyltransferase 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q55FL5, PANTHER:PTHR13693:SF2, PRO:DNx] comment: Category=organism-gene. synonym: "sptA" RELATED Gene-based [UniProtKB:Q55FL5] synonym: "DDB_G0268056" RELATED Gene-based [UniProtKB:Q55FL5] synonym: "Dicty-SPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "SPT1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FL5] synonym: "LCB 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FL5] synonym: "SPT 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FL5] synonym: "serine-palmitoyl-CoA transferase 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FL5] synonym: "long chain base biosynthesis protein 1 (Dictyostelium discoideum)" EXACT [UniProtKB:Q55FL5] xref: UniProtKB:Q55FL5 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template dictyBase:DDB_G0268056 ! sptA (Dictyostelium discoideum) [Term] id: PR:000045580 name: serine palmitoyltransferase 1 phosphorylated 1 (human) def: "A serine palmitoyltransferase 1 (human) that has been phosphorylated at the position equivalent to Tyr-164 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Tyr-164, MOD:00048." [PMID:23629659, iPTMnet:O15269] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23629659). Status=unreviewed. synonym: "hSPTLC1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O15269-1, Tyr-164, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O15269 ! serine palmitoyltransferase 1 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O35704-1 name: serine palmitoyltransferase 1 isoform 1 (mouse) def: "A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD] comment: Category=organism-sequence. synonym: "mSPTLC1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O35704-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000022019 ! serine palmitoyltransferase 1 isoform 1 [Term] id: PR:O35704 name: serine palmitoyltransferase 1 (mouse) def: "A serine palmitoyltransferase 1 that is encoded in the genome of mouse." [OMA:O35704, PRO:HJD] comment: Category=organism-gene. synonym: "Lcb1" RELATED Gene-based [UniProtKB:O35704] synonym: "Sptlc1" RELATED Gene-based [UniProtKB:O35704] synonym: "mSPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "SPT1 (mouse)" EXACT [UniProtKB:O35704] synonym: "LCB 1 (mouse)" EXACT [UniProtKB:O35704] synonym: "SPT 1 (mouse)" EXACT [UniProtKB:O35704] synonym: "serine-palmitoyl-CoA transferase 1 (mouse)" EXACT [UniProtKB:O35704] synonym: "long chain base biosynthesis protein 1 (mouse)" EXACT [UniProtKB:O35704] xref: UniProtKB:O35704 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template MGI:1099431 ! Sptlc1 (mouse) [Term] id: PR:O59682 name: serine palmitoyltransferase 1 (Schizosaccharomyces pombe 972h-) def: "A serine palmitoyltransferase 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O59682, PANTHER:PTHR13693:SF2, PRO:DNx] comment: Category=organism-gene. synonym: "lcb1" RELATED Gene-based [UniProtKB:O59682] synonym: "SPBC18E5.02c" RELATED Gene-based [UniProtKB:O59682] synonym: "SPBC29A3.20c" RELATED Gene-based [UniProtKB:O59682] synonym: "Spom972h-SPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "SPT1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O59682] synonym: "SPT 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O59682] synonym: "long chain base biosynthesis protein 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O59682] xref: UniProtKB:O59682 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template PomBase:SPBC18E5.02c ! lcb1 (Schizosaccharomyces pombe) [Term] id: PR:O15269 name: serine palmitoyltransferase 1 (human) def: "A serine palmitoyltransferase 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-gene. synonym: "LCB1" RELATED Gene-based [UniProtKB:O15269] synonym: "SPTLC1" RELATED Gene-based [UniProtKB:O15269] synonym: "hSPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "SPT1 (human)" EXACT [UniProtKB:O15269] synonym: "LCB 1 (human)" EXACT [UniProtKB:O15269] synonym: "SPT 1 (human)" EXACT [UniProtKB:O15269] synonym: "serine-palmitoyl-CoA transferase 1 (human)" EXACT [UniProtKB:O15269] synonym: "long chain base biosynthesis protein 1 (human)" EXACT [UniProtKB:O15269] xref: UniProtKB:O15269 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template HGNC:11277 ! SPTLC1 (human) [Term] id: PR:P25045 name: serine palmitoyltransferase 1 (yeast) def: "A serine palmitoyltransferase 1 that is encoded in the genome of yeast." [OMA:P25045, PANTHER:PTHR13693:SF2, PRO:DNx] comment: Category=organism-gene. synonym: "END8" RELATED Gene-based [UniProtKB:P25045] synonym: "LCB1" RELATED Gene-based [UniProtKB:P25045] synonym: "TSC2" RELATED Gene-based [UniProtKB:P25045] synonym: "YMR296C" RELATED Gene-based [UniProtKB:P25045] synonym: "ySPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "SPT1 (yeast)" EXACT [UniProtKB:P25045] synonym: "SPT 1 (yeast)" EXACT [UniProtKB:P25045] synonym: "long chain base biosynthesis protein 1 (yeast)" EXACT [UniProtKB:P25045] xref: UniProtKB:P25045 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template SGD:S000004911 ! LCB1 (yeast) [Term] id: PR:000022019 name: serine palmitoyltransferase 1 isoform 1 def: "A serine palmitoyltransferase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35704-1 or a 1:1 ortholog thereof." [PMID:9363775, PRO:HJD] comment: Category=sequence. synonym: "SPTLC1/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000015596 ! serine palmitoyltransferase 1 [Term] id: PR:Q94IB8 name: long chain base biosynthesis protein 1 (Arabidopsis thaliana) def: "A serine palmitoyltransferase 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q94IB8, PANTHER:PTHR13693:SF2, PRO:DNx] comment: Category=organism-gene. synonym: "AP22" RELATED Gene-based [UniProtKB:Q94IB8] synonym: "LCB1" RELATED Gene-based [UniProtKB:Q94IB8] synonym: "FBR11" RELATED Gene-based [UniProtKB:Q94IB8] synonym: "AtLCB1" EXACT [UniProtKB:Q94IB8] synonym: "EMB2779" RELATED Gene-based [UniProtKB:Q94IB8] synonym: "At-SPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "At4g36480" RELATED Gene-based [UniProtKB:Q94IB8] synonym: "C7A10.880" RELATED Gene-based [UniProtKB:Q94IB8] synonym: "protein EMBRYO DEFECTIVE 2779 (Arabidopsis thaliana)" EXACT [UniProtKB:Q94IB8] synonym: "protein FUMONISIN B1 RESISTANT 11 (Arabidopsis thaliana)" EXACT [UniProtKB:Q94IB8] xref: UniProtKB:Q94IB8 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template Araport:AT4G36480 ! LCB1 (Arabidopsis thaliana) [Term] id: PR:P91079 name: serine palmitoyltransferase 1 (worm) def: "A serine palmitoyltransferase 1 that is encoded in the genome of worm." [OMA:P91079, PANTHER:PTHR13693:SF2, PRO:DNx] comment: Category=organism-gene. synonym: "sptl-1" RELATED Gene-based [UniProtKB:P91079] synonym: "C23H3.4" RELATED Gene-based [UniProtKB:P91079] synonym: "SPT1 (worm)" EXACT [UniProtKB:P91079] synonym: "LCB 1 (worm)" EXACT [UniProtKB:P91079] synonym: "SPT 1 (worm)" EXACT [UniProtKB:P91079] synonym: "SPTLC1 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "serine-palmitoyl-CoA transferase 1 (worm)" EXACT [UniProtKB:P91079] synonym: "long chain base biosynthesis protein 1 (worm)" EXACT [UniProtKB:P91079] xref: UniProtKB:P91079 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template WormBase:WBGene00016020 ! sptl-1 (worm) [Term] id: PR:D4A2H2 name: serine palmitoyltransferase 1 (rat) def: "A serine palmitoyltransferase 1 that is encoded in the genome of rat." [OMA:D4A2H2, PRO:DNx] comment: Category=organism-gene. synonym: "Lcb1" RELATED Gene-based [UniProtKB:D4A2H2] synonym: "Sptlc1" RELATED Gene-based [UniProtKB:D4A2H2] synonym: "rSPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "rCG_44191" RELATED Gene-based [UniProtKB:D4A2H2] synonym: "SPT1 (rat)" EXACT [UniProtKB:D4A2H2] synonym: "LCB 1 (rat)" EXACT [UniProtKB:D4A2H2] synonym: "SPT 1 (rat)" EXACT [UniProtKB:D4A2H2] synonym: "serine-palmitoyl-CoA transferase 1 (rat)" EXACT [UniProtKB:D4A2H2] synonym: "long chain base biosynthesis protein 1 (rat)" EXACT [UniProtKB:D4A2H2] xref: UniProtKB:D4A2H2 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template RGD:1307140 ! Sptlc1 (rat)