[Term] id: PR:000015174 name: sodium-coupled monocarboxylate transporter 1 def: "A protein that is a translation product of the human SLC5A8 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "AIT" RELATED Gene-based [] synonym: "SMCT" RELATED Gene-based [] synonym: "SMCT1" RELATED Gene-based [] synonym: "SLC5A8" EXACT PRO-short-label [PRO:DNx] synonym: "apical iodide transporter" EXACT [] synonym: "solute carrier family 5 member 8" EXACT [] synonym: "sodium iodide-related cotransporter" EXACT [] synonym: "electrogenic sodium monocarboxylate cotransporter" EXACT [] xref: IUPHARobj:922 is_a: PR:000000001 ! protein [Term] id: PR:Q8N695 name: sodium-coupled monocarboxylate transporter 1 (human) def: "A sodium-coupled monocarboxylate transporter 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8N695] comment: Category=organism-gene. synonym: "AIT" RELATED Gene-based [UniProtKB:Q8N695] synonym: "SMCT" RELATED Gene-based [UniProtKB:Q8N695] synonym: "SMCT1" RELATED Gene-based [UniProtKB:Q8N695] synonym: "SLC5A8" RELATED Gene-based [UniProtKB:Q8N695] synonym: "hSLC5A8" EXACT PRO-short-label [PRO:DNx] synonym: "apical iodide transporter (human)" EXACT [UniProtKB:Q8N695] synonym: "solute carrier family 5 member 8 (human)" EXACT [UniProtKB:Q8N695] synonym: "sodium iodide-related cotransporter (human)" EXACT [UniProtKB:Q8N695] synonym: "electrogenic sodium monocarboxylate cotransporter (human)" EXACT [UniProtKB:Q8N695] xref: UniProtKB:Q8N695 xref: Reactome:R-HSA-429769 "PR:Q8N695 located_in GO:0005886" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000015174 ! sodium-coupled monocarboxylate transporter 1 relationship: has_gene_template HGNC:19119 ! SLC5A8 (human) [Term] id: PR:000057682 name: sodium-coupled monocarboxylate transporter 1 O-glycosylated 3 (human) def: "A sodium-coupled monocarboxylate transporter 1 (human) that has been O-glycosylated at the residue equivalent to Thr-498 of the amino acid sequence represented by UniProtKB:Q8N695-1, in which the glycan composition is represented by GlyTouCan:G57317CE. Example: UniProtKB:Q8N695-1, Thr-498, MOD:00005~GNO:G57317CE." [GlyGen:Q8N695-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSLC5A8/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8N695-1, Thr-498, MOD:00005~GNO:G57317CE" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q8N695 ! sodium-coupled monocarboxylate transporter 1 (human) relationship: has_part GNO:G57317CE ! G57317CE relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057683 name: sodium-coupled monocarboxylate transporter 1 O-glycosylated 4 (human) def: "A sodium-coupled monocarboxylate transporter 1 (human) that has been O-glycosylated at the residue equivalent to Thr-499 of the amino acid sequence represented by UniProtKB:Q8N695-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q8N695-1, Thr-499, MOD:00005~GNO:G43417UB." [GlyGen:Q8N695-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSLC5A8/OGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8N695-1, Thr-499, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q8N695 ! sodium-coupled monocarboxylate transporter 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057680 name: sodium-coupled monocarboxylate transporter 1 O-glycosylated 1 (human) def: "A sodium-coupled monocarboxylate transporter 1 (human) that has been O-glycosylated at the residue equivalent to Thr-493 of the amino acid sequence represented by UniProtKB:Q8N695-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q8N695-1, Thr-493, MOD:00005~GNO:G43417UB." [GlyGen:Q8N695-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSLC5A8/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8N695-1, Thr-493, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q8N695 ! sodium-coupled monocarboxylate transporter 1 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q3ZMH1 name: sodium-coupled monocarboxylate transporter 1 (zebrafish) def: "A sodium-coupled monocarboxylate transporter 1 that is encoded in the genome of zebrafish." [PRO:DNx] comment: Category=organism-gene. synonym: "smcte" RELATED Gene-based [UniProtKB:Q3ZMH1] synonym: "slc5a8" RELATED Gene-based [UniProtKB:Q3ZMH1] synonym: "zSMCTe" EXACT [UniProtKB:Q3ZMH1] synonym: "slc5a8l" RELATED Gene-based [UniProtKB:Q3ZMH1] synonym: "z-SLC5A8" EXACT PRO-short-label [PRO:DNx] synonym: "zgc:152716" RELATED Gene-based [UniProtKB:Q3ZMH1] synonym: "solute carrier family 5 member 8 (zebrafish)" EXACT [UniProtKB:Q3ZMH1] synonym: "electrogenic sodium monocarboxylate cotransporter (zebrafish)" EXACT [UniProtKB:Q3ZMH1] synonym: "sodium solute symporter family 5 member 8 protein (zebrafish)" EXACT [UniProtKB:Q3ZMH1] xref: UniProtKB:Q3ZMH1 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000015174 ! sodium-coupled monocarboxylate transporter 1 relationship: has_gene_template ZFIN:ZDB-GENE-061110-98 ! slc5a8l (zebrafish) [Term] id: PR:Q8BYF6 name: sodium-coupled monocarboxylate transporter 1 (mouse) def: "A sodium-coupled monocarboxylate transporter 1 that is encoded in the genome of mouse." [OMA:Q8BYF6, PRO:DNx] comment: Category=organism-gene. synonym: "Smct" RELATED Gene-based [UniProtKB:Q8BYF6] synonym: "Smct1" RELATED Gene-based [UniProtKB:Q8BYF6] synonym: "Slc5a8" RELATED Gene-based [UniProtKB:Q8BYF6] synonym: "mSLC5A8" EXACT PRO-short-label [PRO:DNx] synonym: "solute carrier family 5 member 8 (mouse)" EXACT [UniProtKB:Q8BYF6] synonym: "electrogenic sodium monocarboxylate cotransporter (mouse)" EXACT [UniProtKB:Q8BYF6] xref: UniProtKB:Q8BYF6 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000015174 ! sodium-coupled monocarboxylate transporter 1 relationship: has_gene_template MGI:2384916 ! Slc5a8 (mouse) [Term] id: PR:000057681 name: sodium-coupled monocarboxylate transporter 1 O-glycosylated 2 (human) def: "A sodium-coupled monocarboxylate transporter 1 (human) that has been O-glycosylated at the residue equivalent to Thr-498 of the amino acid sequence represented by UniProtKB:Q8N695-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q8N695-1, Thr-498, MOD:00005~GNO:G53434XO." [GlyGen:Q8N695-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hSLC5A8/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q8N695-1, Thr-498, MOD:00005~GNO:G53434XO" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q8N695 ! sodium-coupled monocarboxylate transporter 1 (human) relationship: has_part GNO:G53434XO ! G53434XO relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens