[Term]
id: PR:Q9BYW2-2
name: histone-lysine N-methyltransferase SETD2 isoform h2 (human)
def: "A histone-lysine N-methyltransferase SETD2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BYW2-2." [PRO:DNx, UniProtKB:Q9BYW2]
comment: Category=organism-sequence.
synonym: "hSETD2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BYW2-2
is_a: PR:Q9BYW2 ! histone-lysine N-methyltransferase SETD2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:E9Q5F9-2
name: histone-lysine N-methyltransferase SETD2 isoform m2 (mouse)
def: "A histone-lysine N-methyltransferase SETD2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E9Q5F9-2." [PRO:DNx, UniProtKB:E9Q5F9]
comment: Category=organism-sequence.
synonym: "mSETD2/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:E9Q5F9-2
is_a: PR:E9Q5F9 ! histone-lysine N-methyltransferase SETD2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:E9Q5F9-1
name: histone-lysine N-methyltransferase SETD2 isoform m1 (mouse)
def: "A histone-lysine N-methyltransferase SETD2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E9Q5F9-1." [PRO:DNx, UniProtKB:E9Q5F9]
comment: Category=organism-sequence.
synonym: "mSETD2/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:E9Q5F9-1
is_a: PR:E9Q5F9 ! histone-lysine N-methyltransferase SETD2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9BYW2-1
name: histone-lysine N-methyltransferase SETD2 isoform h1 (human)
def: "A histone-lysine N-methyltransferase SETD2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BYW2-1." [PRO:DNx, UniProtKB:Q9BYW2]
comment: Category=organism-sequence.
synonym: "hSETD2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BYW2-1
is_a: PR:Q9BYW2 ! histone-lysine N-methyltransferase SETD2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BYW2
name: histone-lysine N-methyltransferase SETD2 (human)
def: "A histone-lysine N-methyltransferase SETD2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BYW2]
comment: Category=organism-gene.
synonym: "HIF1" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "HYPB" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "SET2" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "KMT3A" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "SETD2" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "hSET2" EXACT [UniProtKB:Q9BYW2]
synonym: "hSETD2" EXACT PRO-short-label [PRO:DNx]
synonym: "HSPC069" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "KIAA1732" RELATED Gene-based [UniProtKB:Q9BYW2]
synonym: "HIF-1 (human)" EXACT [UniProtKB:Q9BYW2]
synonym: "HIP-1 (human)" BROAD [UniProtKB:Q9BYW2]
synonym: "p231HBP (human)" EXACT [UniProtKB:Q9BYW2]
synonym: "huntingtin yeast partner B (human)" EXACT [UniProtKB:Q9BYW2]
synonym: "lysine N-methyltransferase 3A (human)" EXACT [UniProtKB:Q9BYW2]
synonym: "SET domain-containing protein 2 (human)" EXACT [UniProtKB:Q9BYW2]
synonym: "huntingtin-interacting protein 1 (human)" RELATED [UniProtKB:Q9BYW2]
synonym: "huntingtin-interacting protein B (human)" EXACT [UniProtKB:Q9BYW2]
synonym: "protein-lysine N-methyltransferase SETD2 (human)" EXACT [UniProtKB:Q9BYW2]
xref: UniProtKB:Q9BYW2
xref: Reactome:R-HSA-1183220 "PR:Q9BYW2 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014721 ! histone-lysine N-methyltransferase SETD2
relationship: has_gene_template HGNC:18420 ! SETD2 (human)

[Term]
id: PR:E9Q5F9
name: histone-lysine N-methyltransferase SETD2 (mouse)
def: "A histone-lysine N-methyltransferase SETD2 that is encoded in the genome of mouse." [OMA:E9Q5F9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Kmt3a" RELATED Gene-based [UniProtKB:E9Q5F9]
synonym: "Setd2" RELATED Gene-based [UniProtKB:E9Q5F9]
synonym: "mSETD2" EXACT PRO-short-label [PRO:DNx]
synonym: "Kiaa1732" RELATED Gene-based [UniProtKB:E9Q5F9]
synonym: "lysine N-methyltransferase 3A (mouse)" EXACT [UniProtKB:E9Q5F9]
synonym: "SET domain-containing protein 2 (mouse)" EXACT [UniProtKB:E9Q5F9]
synonym: "protein-lysine N-methyltransferase SETD2 (mouse)" EXACT [UniProtKB:E9Q5F9]
xref: UniProtKB:E9Q5F9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000014721 ! histone-lysine N-methyltransferase SETD2
relationship: has_gene_template MGI:1918177 ! Setd2 (mouse)

[Term]
id: PR:000014721
name: histone-lysine N-methyltransferase SETD2
def: "A protein that is a translation product of the human SETD2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HIF1" RELATED Gene-based []
synonym: "HYPB" RELATED Gene-based []
synonym: "SET2" RELATED Gene-based []
synonym: "HIF-1" EXACT []
synonym: "HIP-1" RELATED []
synonym: "KMT3A" RELATED Gene-based []
synonym: "SETD2" EXACT PRO-short-label [PRO:DNx]
synonym: "HSPC069" RELATED Gene-based []
synonym: "p231HBP" EXACT []
synonym: "KIAA1732" RELATED Gene-based []
synonym: "huntingtin yeast partner B" EXACT []
synonym: "lysine N-methyltransferase 3A" EXACT []
synonym: "SET domain-containing protein 2" EXACT []
synonym: "huntingtin-interacting protein 1" RELATED []
synonym: "huntingtin-interacting protein B" EXACT []
synonym: "protein-lysine N-methyltransferase SETD2" EXACT []
xref: IUPHARobj:2702
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9BYW2-3
name: histone-lysine N-methyltransferase SETD2 isoform h3 (human)
def: "A histone-lysine N-methyltransferase SETD2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BYW2-3." [PRO:DNx, UniProtKB:Q9BYW2]
comment: Category=organism-sequence.
synonym: "hSETD2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BYW2-3
is_a: PR:Q9BYW2 ! histone-lysine N-methyltransferase SETD2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens