[Term]
id: PR:000014306
name: ribonucleoside-diphosphate reductase subunit M2
def: "A ribonucleoside-diphosphate reductase class I, small subunit that is a translation product of the human RRM2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "RR2" RELATED Gene-based []
synonym: "RRM2" EXACT PRO-short-label [PRO:DNx]
synonym: "ribonucleotide reductase small chain" EXACT []
synonym: "ribonucleotide reductase small subunit" EXACT []
xref: IUPHARobj:2631
is_a: PR:000027717 ! ribonucleoside-diphosphate reductase class I, small subunit

[Term]
id: PR:P31350
name: ribonucleoside-diphosphate reductase subunit M2 (human)
def: "A ribonucleoside-diphosphate reductase subunit M2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P31350]
comment: Category=organism-gene.
synonym: "RR2" RELATED Gene-based [UniProtKB:P31350]
synonym: "RRM2" RELATED Gene-based [UniProtKB:P31350]
synonym: "hRRM2" EXACT PRO-short-label [PRO:DNx]
synonym: "ribonucleotide reductase small chain (human)" EXACT [UniProtKB:P31350]
synonym: "ribonucleotide reductase small subunit (human)" EXACT [UniProtKB:P31350]
xref: Reactome:R-HSA-63136 "PR:P31350 located_in GO:0005654"
xref: UniProtKB:P31350
xref: Reactome:R-HSA-73639 "PR:P31350 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000014306 ! ribonucleoside-diphosphate reductase subunit M2
relationship: has_gene_template HGNC:10452 ! RRM2 (human)

[Term]
id: PR:000045750
name: ribonucleoside-diphosphate reductase subunit M2 phosphorylated 1 (human)
def: "A ribonucleoside-diphosphate reductase subunit M2 (human) that has been phosphorylated at the position equivalent to Ser-20 of the amino acid sequence represented by UniProtKB:P31350-1. Example: UniProtKB:P31350-1, Ser-20, MOD:00046." [PMID:17693683, iPTMnet:P31350]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:17693683). Status=unreviewed.
synonym: "hRRM2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P31350-1, Ser-20, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P31350 ! ribonucleoside-diphosphate reductase subunit M2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31350-1
name: ribonucleoside-diphosphate reductase subunit M2 isoform h1 (human)
def: "A ribonucleoside-diphosphate reductase subunit M2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31350-1." [PRO:DNx, UniProtKB:P31350]
comment: Category=organism-sequence.
synonym: "hRRM2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P31350-1
is_a: PR:P31350 ! ribonucleoside-diphosphate reductase subunit M2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P31350-2
name: ribonucleoside-diphosphate reductase subunit M2 isoform h2 (human)
def: "A ribonucleoside-diphosphate reductase subunit M2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P31350-2." [PRO:DNx, UniProtKB:P31350]
comment: Category=organism-sequence.
synonym: "hRRM2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P31350-2
is_a: PR:P31350 ! ribonucleoside-diphosphate reductase subunit M2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens