[Term]
id: PR:Q8IV61
name: Ras guanyl-releasing protein 3 (human)
def: "A Ras guanyl-releasing protein 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IV61]
comment: Category=organism-gene.
synonym: "GRP3" RELATED Gene-based [UniProtKB:Q8IV61]
synonym: "RASGRP3" RELATED Gene-based [UniProtKB:Q8IV61]
synonym: "KIAA0846" RELATED Gene-based [UniProtKB:Q8IV61]
synonym: "hRASGRP3" EXACT PRO-short-label [PRO:DNx]
synonym: "guanine nucleotide exchange factor for Rap1 (human)" BROAD [UniProtKB:Q8IV61]
synonym: "calcium and DAG-regulated guanine nucleotide exchange factor III (human)" EXACT [UniProtKB:Q8IV61]
xref: UniProtKB:Q8IV61
xref: Reactome:R-HSA-1168360 "PR:Q8IV61 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013760 ! Ras guanyl-releasing protein 3
relationship: has_gene_template HGNC:14545 ! RASGRP3 (human)

[Term]
id: PR:000013760
name: Ras guanyl-releasing protein 3
def: "A protein that is a translation product of the human RASGRP3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GRP3" RELATED Gene-based []
synonym: "RASGRP3" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0846" RELATED Gene-based []
synonym: "guanine nucleotide exchange factor for Rap1" RELATED []
synonym: "calcium and DAG-regulated guanine nucleotide exchange factor III" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8IV61-1
name: Ras guanyl-releasing protein 3 isoform h1 (human)
def: "A Ras guanyl-releasing protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IV61-1." [PRO:DNx, UniProtKB:Q8IV61]
comment: Category=organism-sequence.
synonym: "hRASGRP3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IV61-1
is_a: PR:Q8IV61 ! Ras guanyl-releasing protein 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IV61-2
name: Ras guanyl-releasing protein 3 isoform h2 (human)
def: "A Ras guanyl-releasing protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IV61-2." [PRO:DNx, UniProtKB:Q8IV61]
comment: Category=organism-sequence.
synonym: "hRASGRP3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IV61-2
is_a: PR:Q8IV61 ! Ras guanyl-releasing protein 3 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045985
name: Ras guanyl-releasing protein 3 phosphorylated 1 (human)
def: "A Ras guanyl-releasing protein 3 (human) that has been phosphorylated at the position equivalent to Thr-133 of the amino acid sequence represented by UniProtKB:Q8IV61-1. Example: UniProtKB:Q8IV61-1, Thr-133, MOD:00047." [PMID:15657177, iPTMnet:Q8IV61]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15657177). Status=unreviewed.
synonym: "hRASGRP3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IV61-1, Thr-133, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1168362 "PR:000045985 located_in GO:0005886"
is_a: PR:Q8IV61 ! Ras guanyl-releasing protein 3 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens