[Term]
id: PR:000013512
name: paxillin
def: "A protein that is a translation product of the human PXN gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PXN" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:P49023
name: paxillin (human)
def: "A paxillin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49023]
comment: Category=organism-gene.
synonym: "PXN" RELATED Gene-based [UniProtKB:P49023]
synonym: "hPXN" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-180493 "PR:P49023 located_in GO:0005886"
xref: Reactome:R-HSA-210014 "PR:P49023 located_in GO:0005829"
xref: UniProtKB:P49023
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013512 ! paxillin
relationship: has_gene_template HGNC:9718 ! PXN (human)

[Term]
id: PR:000048972
name: paxillin phosphorylated 2 (human)
def: "A paxillin (human) that has been post-translationally modified to include phosphotyrosine at positions 31 and 118 of the amino acid sequence represented by UniProtKB:P49023. UniProtKB:P49023, Tyr-31/Tyr-118, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218693]
comment: Category=organism-modification.
synonym: "hPXN/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49023, Tyr-31/Tyr-118, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5218693 "PR:000048972 located_in GO:0005829"
is_a: PR:P49023 ! paxillin (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045799
name: paxillin phosphorylated 1 (human)
def: "A paxillin (human) that has been phosphorylated at the position equivalent to Ser-244 of the amino acid sequence represented by UniProtKB:P49023-1. Example: UniProtKB:P49023-1, Ser-244, MOD:00046." [PMID:18042622, iPTMnet:P49023]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18042622). Status=unreviewed.
synonym: "hPXN/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P49023-1, Ser-244, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P49023 ! paxillin (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49023-2
name: paxillin isoform Alpha (human)
def: "A paxillin isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPXN/iso:Alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49023-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039573 ! paxillin isoform 2

[Term]
id: PR:P49023-3
name: paxillin isoform Gamma (human)
def: "A paxillin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49023-3." [PRO:DNx, UniProtKB:P49023]
comment: Category=organism-sequence.
synonym: "hPXN/iso:Gamma" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49023-3
is_a: PR:P49023 ! paxillin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49023-1
name: paxillin isoform Beta (human)
def: "A paxillin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49023-1." [PRO:DNx, UniProtKB:P49023]
comment: Category=organism-sequence.
synonym: "hPXN/iso:Beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49023-1
is_a: PR:P49023 ! paxillin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49023-4
name: paxillin isoform h4 (human)
def: "A paxillin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49023-4." [PRO:DNx, UniProtKB:P49023]
comment: Category=organism-sequence.
synonym: "hPXN/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49023-4
is_a: PR:P49023 ! paxillin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens