[Term] id: PR:000040295 name: tyrosine-protein phosphatase non-receptor type 11 isoform 1 def: "A tyrosine-protein phosphatase non-receptor type 11 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06124-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 [Term] id: PR:000048959 name: tyrosine-protein phosphatase non-receptor type 11 phosphorylated 1 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 (human) that has been post-translationally modified to include phosphotyrosine at position 546 of the amino acid sequence represented by UniProtKB:Q06124. UniProtKB:Q06124, Tyr-546, MOD:00048." [PRO:DNx, Reactome:R-HSA-1369081] comment: Category=organism-modification. synonym: "hPTPN11/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q06124, Tyr-546, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-1369081 "PR:000048959 located_in GO:0005829" is_a: PR:Q06124 ! tyrosine-protein phosphatase non-receptor type 11 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000013449 name: tyrosine-protein phosphatase non-receptor type 11 def: "A protein that is a translation product of the human PTPN11 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "shp2" EXACT [] synonym: "PTP2C" RELATED Gene-based [] synonym: "SHP-2" EXACT [] synonym: "PTP-1D" EXACT [] synonym: "PTP-2C" EXACT [] synonym: "PTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "SHPTP2" RELATED Gene-based [] synonym: "SH-PTP2" EXACT [] synonym: "SH-PTP3" EXACT [] synonym: "protein-tyrosine phosphatase 1D" EXACT [] synonym: "protein-tyrosine phosphatase 2C" EXACT [] synonym: "protein-tyrosine phosphatase SYP" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q90687 name: tyrosine-protein phosphatase non-receptor type 11 (chicken) def: "A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of chicken." [OMA:Q90687, PRO:DNx] comment: Category=organism-gene. synonym: "PTPN11" RELATED Gene-based [UniProtKB:Q90687] synonym: "chick-PTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "SH-PTP2 (chicken)" EXACT [UniProtKB:Q90687] synonym: "cSH-PTP2 (chicken)" EXACT [UniProtKB:Q90687] xref: UniProtKB:Q90687 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 relationship: has_gene_template NCBIGene:395815 ! PTPN11 (chicken) [Term] id: PR:P35235 name: tyrosine-protein phosphatase non-receptor type 11 (mouse) def: "A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of mouse." [OMA:P35235, PRO:DNx] comment: Category=organism-gene. synonym: "Ptpn11" RELATED Gene-based [UniProtKB:P35235] synonym: "mPTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "Shp2 (mouse)" EXACT [UniProtKB:P35235] synonym: "SHP-2 (mouse)" EXACT [UniProtKB:P35235] synonym: "SH-PTP2 (mouse)" EXACT [UniProtKB:P35235] synonym: "protein-tyrosine phosphatase SYP (mouse)" EXACT [UniProtKB:P35235] xref: UniProtKB:P35235 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 relationship: has_gene_template MGI:99511 ! Ptpn11 (mouse) [Term] id: PR:P29349-3 name: tyrosine-protein phosphatase corkscrew isoform 3 (fruit fly) def: "A tyrosine-protein phosphatase corkscrew (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29349-3." [PRO:DNx, UniProtKB:P29349] comment: Category=organism-sequence. synonym: "fly-PTPN11/iso:3" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase corkscrew isoform C (fruit fly)" EXACT [UniProtKB:P29349] xref: UniProtKB:P29349-3 is_a: PR:P29349 ! tyrosine-protein phosphatase corkscrew (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P29349-2 name: tyrosine-protein phosphatase corkscrew isoform 1 (fruit fly) def: "A tyrosine-protein phosphatase corkscrew (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29349-2." [PRO:DNx, UniProtKB:P29349] comment: Category=organism-sequence. synonym: "fly-PTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase corkscrew isoform A (fruit fly)" EXACT [UniProtKB:P29349] synonym: "tyrosine-protein phosphatase corkscrew isoform Y1229 (fruit fly)" EXACT [UniProtKB:P29349] xref: UniProtKB:P29349-2 is_a: PR:P29349 ! tyrosine-protein phosphatase corkscrew (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P29349-1 name: tyrosine-protein phosphatase corkscrew isoform 2 (fruit fly) def: "A tyrosine-protein phosphatase corkscrew (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29349-1." [PRO:DNx, UniProtKB:P29349] comment: Category=organism-sequence. synonym: "fly-PTPN11/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P29349-1 is_a: PR:P29349 ! tyrosine-protein phosphatase corkscrew (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P29349-4 name: tyrosine-protein phosphatase corkscrew isoform 4 (fruit fly) def: "A tyrosine-protein phosphatase corkscrew (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29349-4." [PRO:DNx, UniProtKB:P29349] comment: Category=organism-sequence. synonym: "fly-PTPN11/iso:4" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase corkscrew isoform B (fruit fly)" EXACT [UniProtKB:P29349] synonym: "tyrosine-protein phosphatase corkscrew isoform 4A (fruit fly)" EXACT [UniProtKB:P29349] xref: UniProtKB:P29349-4 is_a: PR:P29349 ! tyrosine-protein phosphatase corkscrew (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P35235-2 name: tyrosine-protein phosphatase non-receptor type 11 isoform 2 (mouse) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 2 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mPTPN11/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35235-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000040296 ! tyrosine-protein phosphatase non-receptor type 11 isoform 2 [Term] id: PR:Q90687-1 name: tyrosine-protein phosphatase non-receptor type 11 isoform 1 (chicken) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 2 that is encoded in the genome of chicken." [PRO:DNx] comment: Category=organism-sequence. synonym: "chick-PTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q90687-1 intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus intersection_of: PR:000040296 ! tyrosine-protein phosphatase non-receptor type 11 isoform 2 [Term] id: PR:P35235-1 name: tyrosine-protein phosphatase non-receptor type 11 isoform 1 (mouse) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mPTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P35235-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000040295 ! tyrosine-protein phosphatase non-receptor type 11 isoform 1 [Term] id: PR:Q06124 name: tyrosine-protein phosphatase non-receptor type 11 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q06124] comment: Category=organism-gene. synonym: "PTP2C" RELATED Gene-based [UniProtKB:Q06124] synonym: "PTPN11" RELATED Gene-based [UniProtKB:Q06124] synonym: "SHPTP2" RELATED Gene-based [UniProtKB:Q06124] synonym: "hPTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "Shp2 (human)" EXACT [UniProtKB:Q06124] synonym: "SHP-2 (human)" EXACT [UniProtKB:Q06124] synonym: "PTP-1D (human)" EXACT [UniProtKB:Q06124] synonym: "PTP-2C (human)" EXACT [UniProtKB:Q06124] synonym: "SH-PTP2 (human)" EXACT [UniProtKB:Q06124] synonym: "SH-PTP3 (human)" EXACT [UniProtKB:Q06124] synonym: "protein-tyrosine phosphatase 1D (human)" EXACT [UniProtKB:Q06124] synonym: "protein-tyrosine phosphatase 2C (human)" EXACT [UniProtKB:Q06124] xref: Reactome:R-HSA-162563 "PR:Q06124 located_in GO:0005829" xref: Reactome:R-HSA-8937745 "PR:Q06124 located_in GO:0005654" xref: UniProtKB:Q06124 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 relationship: has_gene_template HGNC:9644 ! PTPN11 (human) [Term] id: PR:P41499 name: tyrosine-protein phosphatase non-receptor type 11 (rat) def: "A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of rat." [OMA:P41499, PANTHER:PTHR19134:SF64, PRO:DNx] comment: Category=organism-gene. synonym: "Ptpn11" RELATED Gene-based [UniProtKB:P41499] synonym: "rPTPN11" EXACT PRO-short-label [PRO:DNx] synonym: "Shp2 (rat)" EXACT [UniProtKB:P41499] synonym: "SHP-2 (rat)" EXACT [UniProtKB:P41499] synonym: "PTP-1D (rat)" EXACT [UniProtKB:P41499] synonym: "SH-PTP2 (rat)" EXACT [UniProtKB:P41499] synonym: "protein-tyrosine phosphatase 1D (rat)" EXACT [UniProtKB:P41499] synonym: "protein-tyrosine phosphatase SYP (rat)" EXACT [UniProtKB:P41499] xref: UniProtKB:P41499 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 relationship: has_gene_template RGD:3447 ! Ptpn11 (rat) [Term] id: PR:Q06124-2 name: tyrosine-protein phosphatase non-receptor type 11 isoform 2 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 2 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPTPN11/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase non-receptor type 11 isoform PTP2C (human)" EXACT [UniProtKB:Q06124] xref: UniProtKB:Q06124-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040296 ! tyrosine-protein phosphatase non-receptor type 11 isoform 2 [Term] id: PR:Q06124-3 name: tyrosine-protein phosphatase non-receptor type 11 isoform h3 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06124-3." [PRO:DNx, UniProtKB:Q06124] comment: Category=organism-sequence. synonym: "hPTPN11/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q06124-3 is_a: PR:Q06124 ! tyrosine-protein phosphatase non-receptor type 11 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q06124-1 name: tyrosine-protein phosphatase non-receptor type 11 isoform 1 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase non-receptor type 11 isoform PTP2Ci (human)" EXACT [UniProtKB:Q06124] xref: UniProtKB:Q06124-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000040295 ! tyrosine-protein phosphatase non-receptor type 11 isoform 1 [Term] id: PR:P41499-1 name: tyrosine-protein phosphatase non-receptor type 11 isoform 1 (rat) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPTPN11/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase non-receptor type 11 isoform PTP1Di (rat)" EXACT [UniProtKB:P41499] xref: UniProtKB:P41499-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000040295 ! tyrosine-protein phosphatase non-receptor type 11 isoform 1 [Term] id: PR:000048960 name: tyrosine-protein phosphatase non-receptor type 11 phosphorylated 2 (human) def: "A tyrosine-protein phosphatase non-receptor type 11 (human) that has been post-translationally modified to include phosphotyrosine at positions 546 and 584 of the amino acid sequence represented by UniProtKB:Q06124. UniProtKB:Q06124, Tyr-546/Tyr-584, MOD:00048." [PRO:DNx, Reactome:R-HSA-162573] comment: Category=organism-modification. synonym: "hPTPN11/Phos:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q06124, Tyr-546/Tyr-584, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-162573 "PR:000048960 located_in GO:0005829" is_a: PR:Q06124 ! tyrosine-protein phosphatase non-receptor type 11 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000040296 name: tyrosine-protein phosphatase non-receptor type 11 isoform 2 def: "A tyrosine-protein phosphatase non-receptor type 11 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q06124-2 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PTPN11/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 [Term] id: PR:P41499-2 name: tyrosine-protein phosphatase non-receptor type 11 isoform 2 (rat) def: "A tyrosine-protein phosphatase non-receptor type 11 isoform 2 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPTPN11/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "tyrosine-protein phosphatase non-receptor type 11 isoform PTP1D (rat)" EXACT [UniProtKB:P41499] xref: UniProtKB:P41499-2 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000040296 ! tyrosine-protein phosphatase non-receptor type 11 isoform 2 [Term] id: PR:P29349 name: tyrosine-protein phosphatase corkscrew (fruit fly) def: "A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of fruit fly." [OMA:P29349, PANTHER:PTHR19134:SF64, PRO:DNx] comment: Category=organism-gene. synonym: "csw" RELATED Gene-based [UniProtKB:P29349] synonym: "CG3954" RELATED Gene-based [UniProtKB:P29349] synonym: "fly-PTPN11" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P29349 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000013449 ! tyrosine-protein phosphatase non-receptor type 11 relationship: has_gene_template FlyBase:FBgn0000382 ! csw (fruit fly)