[Term]
id: PR:O14744
name: protein arginine N-methyltransferase 5 (human)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14744]
comment: Category=organism-gene.
synonym: "JBP1" RELATED Gene-based [UniProtKB:O14744]
synonym: "SKB1" RELATED Gene-based [UniProtKB:O14744]
synonym: "IBP72" RELATED Gene-based [UniProtKB:O14744]
synonym: "PRMT5" RELATED Gene-based [UniProtKB:O14744]
synonym: "hPRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "HRMT1L5" RELATED Gene-based [UniProtKB:O14744]
synonym: "SKB1Hs (human)" EXACT [UniProtKB:O14744]
synonym: "SKB1 homolog (human)" EXACT [UniProtKB:O14744]
synonym: "Jak-binding protein 1 (human)" EXACT [UniProtKB:O14744]
synonym: "72 kDa ICln-binding protein (human)" EXACT [UniProtKB:O14744]
synonym: "Shk1 kinase-binding protein 1 homolog (human)" EXACT [UniProtKB:O14744]
synonym: "histone-arginine N-methyltransferase PRMT5 (human)" EXACT [UniProtKB:O14744]
xref: Reactome:R-HSA-191876 "PR:O14744 located_in GO:0005829"
xref: Reactome:R-HSA-5205609 "PR:O14744 located_in GO:0005654"
xref: UniProtKB:O14744
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template HGNC:10894 ! PRMT5 (human)

[Term]
id: PR:Q9U6Y9-1
name: protein arginine N-methyltransferase 5 isoform 1 (fruit fly)
def: "A protein arginine N-methyltransferase 5 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9U6Y9-1." [PRO:DNx, UniProtKB:Q9U6Y9]
comment: Category=organism-sequence.
synonym: "fly-PRMT5/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein arginine N-methyltransferase 5 isoform A (fruit fly)" EXACT [UniProtKB:Q9U6Y9]
xref: UniProtKB:Q9U6Y9-1
is_a: PR:Q9U6Y9 ! protein arginine N-methyltransferase 5 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P78963
name: protein arginine N-methyltransferase skb1 (Schizosaccharomyces pombe 972h-)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P78963, PANTHER:PTHR10738:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "rmt5" RELATED Gene-based [UniProtKB:P78963]
synonym: "skb1" RELATED Gene-based [UniProtKB:P78963]
synonym: "SPBC16H5.11c" RELATED Gene-based [UniProtKB:P78963]
synonym: "Spom972h-PRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "type II PRMT (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P78963]
synonym: "Shk1 kinase-binding protein 1 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P78963]
synonym: "type II protein arginine N-methyltransferase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P78963]
xref: UniProtKB:P78963
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template PomBase:SPBC16H5.11c ! skb1 (Schizosaccharomyces pombe)

[Term]
id: PR:Q9U6Y9-2
name: protein arginine N-methyltransferase 5 isoform 2 (fruit fly)
def: "A protein arginine N-methyltransferase 5 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9U6Y9-2." [PRO:DNx, UniProtKB:Q9U6Y9]
comment: Category=organism-sequence.
synonym: "fly-PRMT5/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "protein arginine N-methyltransferase 5 isoform B (fruit fly)" EXACT [UniProtKB:Q9U6Y9]
xref: UniProtKB:Q9U6Y9-2
is_a: PR:Q9U6Y9 ! protein arginine N-methyltransferase 5 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:Q8CIG8
name: protein arginine N-methyltransferase 5 (mouse)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of mouse." [OMA:Q8CIG8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Jbp1" RELATED Gene-based [UniProtKB:Q8CIG8]
synonym: "Skb1" RELATED Gene-based [UniProtKB:Q8CIG8]
synonym: "Prmt5" RELATED Gene-based [UniProtKB:Q8CIG8]
synonym: "mPRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "SKB1 homolog (mouse)" EXACT [UniProtKB:Q8CIG8]
synonym: "Jak-binding protein 1 (mouse)" EXACT [UniProtKB:Q8CIG8]
synonym: "Shk1 kinase-binding protein 1 homolog (mouse)" EXACT [UniProtKB:Q8CIG8]
synonym: "histone-arginine N-methyltransferase PRMT5 (mouse)" EXACT [UniProtKB:Q8CIG8]
xref: UniProtKB:Q8CIG8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template MGI:1351645 ! Prmt5 (mouse)

[Term]
id: PR:P46580
name: protein arginine N-methyltransferase 5 (worm)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of worm." [OMA:P46580, PANTHER:PTHR10738:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "prmt-5" RELATED Gene-based [UniProtKB:P46580]
synonym: "tag-251" RELATED Gene-based [UniProtKB:P46580]
synonym: "C34E10.5" RELATED Gene-based [UniProtKB:P46580]
synonym: "PRMT5 (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P46580
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template WormBase:WBGene00016408 ! prmt-5 (worm)

[Term]
id: PR:Q54KI3
name: protein arginine N-methyltransferase 5 (Dictyostelium discoideum)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54KI3, PANTHER:PTHR10738:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "prmt5" RELATED Gene-based [UniProtKB:Q54KI3]
synonym: "Dicty-PRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0287327" RELATED Gene-based [UniProtKB:Q54KI3]
xref: UniProtKB:Q54KI3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template dictyBase:DDB_G0287327 ! prmt5 (Dictyostelium discoideum)

[Term]
id: PR:P38274
name: protein arginine N-methyltransferase HSL7 (yeast)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of yeast." [OMA:P38274, PANTHER:PTHR10738:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "HSL7" RELATED Gene-based [UniProtKB:P38274]
synonym: "yPRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "YBR1008" RELATED Gene-based [UniProtKB:P38274]
synonym: "YBR133C" RELATED Gene-based [UniProtKB:P38274]
synonym: "type II PRMT (yeast)" EXACT [UniProtKB:P38274]
synonym: "histone synthetic lethal protein 7 (yeast)" EXACT [UniProtKB:P38274]
synonym: "type II protein arginine N-methyltransferase (yeast)" EXACT [UniProtKB:P38274]
xref: UniProtKB:P38274
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template SGD:S000000337 ! HSL7 (yeast)

[Term]
id: PR:000037995
name: protein arginine N-methyltransferase 5 isoform 1
def: "A protein arginine N-methyltransferase 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14744-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PRMT5/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000013255 ! protein arginine N-methyltransferase 5

[Term]
id: PR:Q9U6Y9
name: protein arginine N-methyltransferase 5 (fruit fly)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of fruit fly." [OMA:Q9U6Y9, PANTHER:PTHR10738:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "csul" RELATED Gene-based [UniProtKB:Q9U6Y9]
synonym: "DART5" RELATED Gene-based [UniProtKB:Q9U6Y9]
synonym: "CG3730" RELATED Gene-based [UniProtKB:Q9U6Y9]
synonym: "fly-PRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "JBP1 homolog (fruit fly)" EXACT [UniProtKB:Q9U6Y9]
synonym: "protein arginine N-methyltransferase capsuleen (fruit fly)" EXACT [UniProtKB:Q9U6Y9]
xref: UniProtKB:Q9U6Y9
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template FlyBase:FBgn0015925 ! csul (fruit fly)

[Term]
id: PR:Q8GWT4-3
name: protein arginine N-methyltransferase 1.5 isoform 3 (Arabidopsis thaliana)
def: "A protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8GWT4-3." [PRO:DNx, UniProtKB:Q8GWT4]
comment: Category=organism-sequence.
synonym: "At-PRMT5/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8GWT4-3
is_a: PR:Q8GWT4 ! protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:Q8CIG8-1
name: protein arginine N-methyltransferase 5 isoform 1 (mouse)
def: "A protein arginine N-methyltransferase 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPRMT5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CIG8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037995 ! protein arginine N-methyltransferase 5 isoform 1

[Term]
id: PR:000048929
name: protein arginine N-methyltransferase 5 phosphorylated 1 (human)
def: "A protein arginine N-methyltransferase 5 (human) that has been post-translationally modified to include phosphotyrosine at positions 297, 304 and 307 of the amino acid sequence represented by UniProtKB:O14744. UniProtKB:O14744, Tyr-297/Tyr-304/Tyr-307, MOD:00048." [PRO:DNx, Reactome:R-HSA-5211300]
comment: Category=organism-modification.
synonym: "hPRMT5/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14744, Tyr-297/Tyr-304/Tyr-307, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5211300 "PR:000048929 located_in GO:0005654"
is_a: PR:O14744 ! protein arginine N-methyltransferase 5 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14744-5
name: protein arginine N-methyltransferase 5 isoform h5 (human)
def: "A protein arginine N-methyltransferase 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14744-5." [PRO:DNx, UniProtKB:O14744]
comment: Category=organism-sequence.
synonym: "hPRMT5/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14744-5
is_a: PR:O14744 ! protein arginine N-methyltransferase 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14744-4
name: protein arginine N-methyltransferase 5 isoform h4 (human)
def: "A protein arginine N-methyltransferase 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14744-4." [PRO:DNx, UniProtKB:O14744]
comment: Category=organism-sequence.
synonym: "hPRMT5/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14744-4
is_a: PR:O14744 ! protein arginine N-methyltransferase 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14744-3
name: protein arginine N-methyltransferase 5 isoform h3 (human)
def: "A protein arginine N-methyltransferase 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14744-3." [PRO:DNx, UniProtKB:O14744]
comment: Category=organism-sequence.
synonym: "hPRMT5/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14744-3
is_a: PR:O14744 ! protein arginine N-methyltransferase 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14744-2
name: protein arginine N-methyltransferase 5 isoform h2 (human)
def: "A protein arginine N-methyltransferase 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14744-2." [PRO:DNx, UniProtKB:O14744]
comment: Category=organism-sequence.
synonym: "hPRMT5/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14744-2
is_a: PR:O14744 ! protein arginine N-methyltransferase 5 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O14744-1
name: protein arginine N-methyltransferase 5 isoform 1 (human)
def: "A protein arginine N-methyltransferase 5 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPRMT5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14744-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037995 ! protein arginine N-methyltransferase 5 isoform 1

[Term]
id: PR:Q8GWT4-1
name: protein arginine N-methyltransferase 1.5 isoform 1 (Arabidopsis thaliana)
def: "A protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8GWT4-1." [PRO:DNx, UniProtKB:Q8GWT4]
comment: Category=organism-sequence.
synonym: "At-PRMT5/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8GWT4-1
is_a: PR:Q8GWT4 ! protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:Q8GWT4
name: protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana)
def: "A protein arginine N-methyltransferase 5 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q8GWT4, PANTHER:PTHR10738:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "SKB1" RELATED Gene-based [UniProtKB:Q8GWT4]
synonym: "PMRT5" RELATED Gene-based [UniProtKB:Q8GWT4]
synonym: "PMRT15" RELATED Gene-based [UniProtKB:Q8GWT4]
synonym: "AtPMRT5" EXACT [UniProtKB:Q8GWT4]
synonym: "At-PRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "AtPMRT15" EXACT [UniProtKB:Q8GWT4]
synonym: "F6E21.40" RELATED Gene-based [UniProtKB:Q8GWT4]
synonym: "At4g31120" RELATED Gene-based [UniProtKB:Q8GWT4]
synonym: "Shk1 kinase-binding protein 1 homolog (Arabidopsis thaliana)" EXACT [UniProtKB:Q8GWT4]
xref: UniProtKB:Q8GWT4
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
relationship: has_gene_template Araport:AT4G31120 ! PMRT15 (Arabidopsis thaliana)

[Term]
id: PR:000013255
name: protein arginine N-methyltransferase 5
def: "A protein that is a translation product of the human PRMT5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "JBP1" RELATED Gene-based []
synonym: "SKB1" RELATED Gene-based []
synonym: "IBP72" RELATED Gene-based []
synonym: "PRMT5" EXACT PRO-short-label [PRO:DNx]
synonym: "SKB1Hs" EXACT []
synonym: "HRMT1L5" RELATED Gene-based []
synonym: "SKB1 homolog" EXACT []
synonym: "Jak-binding protein 1" EXACT []
synonym: "72 kDa ICln-binding protein" EXACT []
synonym: "shk1 kinase-binding protein 1 homolog" EXACT []
synonym: "histone-arginine N-methyltransferase PRMT5" EXACT []
xref: IUPHARobj:1256
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8GWT4-2
name: protein arginine N-methyltransferase 1.5 isoform 2 (Arabidopsis thaliana)
def: "A protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8GWT4-2." [PRO:DNx, UniProtKB:Q8GWT4]
comment: Category=organism-sequence.
synonym: "At-PRMT5/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8GWT4-2
is_a: PR:Q8GWT4 ! protein arginine N-methyltransferase 1.5 (Arabidopsis thaliana)
relationship: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana

[Term]
id: PR:000021101
name: protein arginine N-methyltransferase 5, initiator methionine removed form
def: "A protein arginine N-methyltransferase 5 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "PRMT5/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000013255 ! protein arginine N-methyltransferase 5
intersection_of: lacks_part PR:000021937 ! initiator methionine