[Term]
id: PR:000028604
name: DNA polymerase beta acetylated 1 (human)
def: "A DNA polymerase beta acetylated 1 in human. UniProtKB:P06746, Lys-72, MOD:00064." [KAT:P06746, PMID:12453427, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102).
synonym: "hPOLB/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06746, Lys-72, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028603 ! DNA polymerase beta acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000045373
name: DNA polymerase beta unacetylated 1 (human)
def: "A DNA polymerase beta (human) that lacks acetylation on the residue equivalent to Lys-72 of the amino acid sequence represented by UniProtKB:P06746. UniProtKB:P06746, Lys-72, PR:000026291." [PMID:12453427, PRO:CNA]
comment: Category=organism-modification.
synonym: "hPOLB/UnAc:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06746, Lys-72, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "DNA polymerase beta unmodified form (human)" EXACT []
is_a: PR:P06746 ! DNA polymerase beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012962
name: DNA polymerase beta
def: "A protein that is a translation product of the human POLB gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "POLB" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000048840
name: DNA polymerase beta, initiator methionine removed ubiquitinated form (human)
def: "A DNA polymerase beta (human) that has had the initiator methionine removed and that includes at least one ubiquitinated lysine. UniProtKB:P06746, 2-335, MOD:01148." [PRO:DNx, Reactome:R-HSA-6783152]
comment: Category=organism-modification.
synonym: "hPOLB/InitMet-/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06746, 2-335, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6783152 "PR:000048840 located_in GO:0005654"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P06746 ! DNA polymerase beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06746-1
name: DNA polymerase beta isoform 1 (human)
def: "A DNA polymerase beta isoform 1 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-sequence.
synonym: "hPOLB/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06746-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028601 ! DNA polymerase beta isoform 1

[Term]
id: PR:000048839
name: DNA polymerase beta, initiator methionine removed form (human)
def: "A DNA polymerase beta (human) that has had the initiator methionine removed. UniProtKB:P06746, 2-335." [PRO:DNx, Reactome:R-HSA-53845]
comment: Category=organism-modification.
synonym: "hPOLB/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06746, 2-335" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-53845 "PR:000048839 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P06746 ! DNA polymerase beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P06746
name: DNA polymerase beta (human)
def: "A DNA polymerase beta that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-gene.
synonym: "POLB" RELATED Gene-based [UniProtKB:P06746]
synonym: "hPOLB" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P06746
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012962 ! DNA polymerase beta
relationship: has_gene_template HGNC:9174 ! POLB (human)