[Term]
id: PR:O00444
name: serine/threonine-protein kinase PLK4 (human)
def: "A serine/threonine-protein kinase PLK4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00444]
comment: Category=organism-gene.
synonym: "SAK" RELATED Gene-based [UniProtKB:O00444]
synonym: "PLK4" RELATED Gene-based [UniProtKB:O00444]
synonym: "STK18" RELATED Gene-based [UniProtKB:O00444]
synonym: "hPLK4" EXACT PRO-short-label [PRO:DNx]
synonym: "PLK-4 (human)" EXACT [UniProtKB:O00444]
synonym: "Polo-like kinase 4 (human)" EXACT [UniProtKB:O00444]
synonym: "serine/threonine-protein kinase 18 (human)" EXACT [UniProtKB:O00444]
synonym: "serine/threonine-protein kinase Sak (human)" EXACT [UniProtKB:O00444]
xref: Reactome:R-HSA-380286 "PR:O00444 located_in GO:0005829"
xref: DTO:03100433
xref: UniProtKB:O00444
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012873 ! serine/threonine-protein kinase PLK4
relationship: has_gene_template HGNC:11397 ! PLK4 (human)

[Term]
id: PR:000045561
name: serine/threonine-protein kinase PLK4 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase PLK4 (human) that has been phosphorylated at the position equivalent to Ser-305 of the amino acid sequence represented by UniProtKB:O00444-1. Example: UniProtKB:O00444-1, Ser-305, MOD:00046." [PMID:20032307, iPTMnet:O00444]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20032307). Status=unreviewed.
synonym: "hPLK4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00444-1, Ser-305, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00444-3
name: serine/threonine-protein kinase PLK4 isoform h3 (human)
def: "A serine/threonine-protein kinase PLK4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00444-3." [PRO:DNx, UniProtKB:O00444]
comment: Category=organism-sequence.
synonym: "hPLK4/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00444-3
is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00444-2
name: serine/threonine-protein kinase PLK4 isoform h2 (human)
def: "A serine/threonine-protein kinase PLK4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00444-2." [PRO:DNx, UniProtKB:O00444]
comment: Category=organism-sequence.
synonym: "hPLK4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00444-2
is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000012873
name: serine/threonine-protein kinase PLK4
def: "A protein that is a translation product of the human PLK4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SAK" RELATED Gene-based []
synonym: "PLK4" EXACT PRO-short-label [PRO:DNx]
synonym: "PLK-4" EXACT []
synonym: "STK18" RELATED Gene-based []
synonym: "Polo-like kinase 4" EXACT []
synonym: "serine/threonine-protein kinase 18" EXACT []
synonym: "serine/threonine-protein kinase Sak" EXACT []
xref: IUPHARobj:2171
is_a: PR:000000001 ! protein

[Term]
id: PR:O00444-1
name: serine/threonine-protein kinase PLK4 isoform h1 (human)
def: "A serine/threonine-protein kinase PLK4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00444-1." [PRO:DNx, UniProtKB:O00444]
comment: Category=organism-sequence.
synonym: "hPLK4/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00444-1
is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens