[Term] id: PR:B2GUY1 name: serine/threonine-protein kinase PLK4 (rat) def: "A serine/threonine-protein kinase PLK4 that is encoded in the genome of rat." [OMA:B2GUY1, PRO:DNx] comment: Category=organism-gene. synonym: "Sak" RELATED Gene-based [UniProtKB:B2GUY1] synonym: "Plk4" RELATED Gene-based [UniProtKB:B2GUY1] synonym: "rPLK4" EXACT PRO-short-label [PRO:DNx] synonym: "PLK-4 (rat)" EXACT [UniProtKB:B2GUY1] synonym: "Polo-like kinase 4 (rat)" EXACT [UniProtKB:B2GUY1] synonym: "serine/threonine-protein kinase Sak (rat)" EXACT [UniProtKB:B2GUY1] xref: UniProtKB:B2GUY1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012873 ! serine/threonine-protein kinase PLK4 relationship: has_gene_template RGD:1305390 ! Plk4 (rat) [Term] id: PR:O00444 name: serine/threonine-protein kinase PLK4 (human) def: "A serine/threonine-protein kinase PLK4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00444] comment: Category=organism-gene. synonym: "SAK" RELATED Gene-based [UniProtKB:O00444] synonym: "PLK4" RELATED Gene-based [UniProtKB:O00444] synonym: "STK18" RELATED Gene-based [UniProtKB:O00444] synonym: "hPLK4" EXACT PRO-short-label [PRO:DNx] synonym: "PLK-4 (human)" EXACT [UniProtKB:O00444] synonym: "Polo-like kinase 4 (human)" EXACT [UniProtKB:O00444] synonym: "serine/threonine-protein kinase 18 (human)" EXACT [UniProtKB:O00444] synonym: "serine/threonine-protein kinase Sak (human)" EXACT [UniProtKB:O00444] xref: Reactome:R-HSA-380286 "PR:O00444 located_in GO:0005829" xref: DTO:03100433 xref: UniProtKB:O00444 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012873 ! serine/threonine-protein kinase PLK4 relationship: has_gene_template HGNC:11397 ! PLK4 (human) [Term] id: PR:000045561 name: serine/threonine-protein kinase PLK4 phosphorylated 1 (human) def: "A serine/threonine-protein kinase PLK4 (human) that has been phosphorylated at the position equivalent to Ser-305 of the amino acid sequence represented by UniProtKB:O00444-1. Example: UniProtKB:O00444-1, Ser-305, MOD:00046." [PMID:20032307, iPTMnet:O00444] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20032307). Status=unreviewed. synonym: "hPLK4/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O00444-1, Ser-305, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O00444-3 name: serine/threonine-protein kinase PLK4 isoform h3 (human) def: "A serine/threonine-protein kinase PLK4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00444-3." [PRO:DNx, UniProtKB:O00444] comment: Category=organism-sequence. synonym: "hPLK4/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O00444-3 is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O00444-2 name: serine/threonine-protein kinase PLK4 isoform h2 (human) def: "A serine/threonine-protein kinase PLK4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00444-2." [PRO:DNx, UniProtKB:O00444] comment: Category=organism-sequence. synonym: "hPLK4/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O00444-2 is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q64702-2 name: serine/threonine-protein kinase PLK4 isoform m2 (mouse) def: "A serine/threonine-protein kinase PLK4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64702-2." [PRO:DNx, UniProtKB:Q64702] comment: Category=organism-sequence. synonym: "mPLK4/iso:m2" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase PLK4 isoform Sak-b (mouse)" EXACT [UniProtKB:Q64702] xref: UniProtKB:Q64702-2 is_a: PR:Q64702 ! serine/threonine-protein kinase PLK4 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:000012873 name: serine/threonine-protein kinase PLK4 def: "A protein that is a translation product of the human PLK4 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "SAK" RELATED Gene-based [] synonym: "PLK4" EXACT PRO-short-label [PRO:DNx] synonym: "PLK-4" EXACT [] synonym: "STK18" RELATED Gene-based [] synonym: "Polo-like kinase 4" EXACT [] synonym: "serine/threonine-protein kinase 18" EXACT [] synonym: "serine/threonine-protein kinase Sak" EXACT [] xref: IUPHARobj:2171 is_a: PR:000000001 ! protein [Term] id: PR:Q7ZVS3 name: serine/threonine-protein kinase PLK4 (zebrafish) def: "A serine/threonine-protein kinase PLK4 that is encoded in the genome of zebrafish." [OMA:Q7ZVS3, PRO:DNx] comment: Category=organism-gene. synonym: "sak" RELATED Gene-based [UniProtKB:Q7ZVS3] synonym: "plk4" RELATED Gene-based [UniProtKB:Q7ZVS3] synonym: "z-PLK4" EXACT PRO-short-label [PRO:DNx] synonym: "PLK-4 (zebrafish)" EXACT [UniProtKB:Q7ZVS3] synonym: "Polo-like kinase 4 (zebrafish)" EXACT [UniProtKB:Q7ZVS3] synonym: "serine/threonine-protein kinase Sak (zebrafish)" EXACT [UniProtKB:Q7ZVS3] xref: UniProtKB:Q7ZVS3 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000012873 ! serine/threonine-protein kinase PLK4 relationship: has_gene_template ZFIN:ZDB-GENE-030619-14 ! plk4 (zebrafish) [Term] id: PR:Q64702-1 name: serine/threonine-protein kinase PLK4 isoform m1 (mouse) def: "A serine/threonine-protein kinase PLK4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64702-1." [PRO:DNx, UniProtKB:Q64702] comment: Category=organism-sequence. synonym: "mPLK4/iso:m1" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase PLK4 isoform Sak-a (mouse)" EXACT [UniProtKB:Q64702] xref: UniProtKB:Q64702-1 is_a: PR:Q64702 ! serine/threonine-protein kinase PLK4 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q64702 name: serine/threonine-protein kinase PLK4 (mouse) def: "A serine/threonine-protein kinase PLK4 that is encoded in the genome of mouse." [OMA:Q64702, PMID:11301255, PRO:CNA] comment: Category=organism-gene. synonym: "Sak" RELATED Gene-based [UniProtKB:Q64702] synonym: "Plk4" RELATED Gene-based [UniProtKB:Q64702] synonym: "Stk18" RELATED Gene-based [UniProtKB:Q64702] synonym: "mPLK4" EXACT PRO-short-label [PRO:DNx] synonym: "PLK-4 (mouse)" EXACT [UniProtKB:Q64702] synonym: "Polo-like kinase 4 (mouse)" EXACT [UniProtKB:Q64702] synonym: "serine/threonine-protein kinase 18 (mouse)" EXACT [UniProtKB:Q64702] synonym: "serine/threonine-protein kinase Sak (mouse)" EXACT [UniProtKB:Q64702] xref: UniProtKB:Q64702 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012873 ! serine/threonine-protein kinase PLK4 relationship: has_gene_template MGI:101783 ! Plk4 (mouse) [Term] id: PR:Q64702-3 name: serine/threonine-protein kinase PLK4 isoform m3 (mouse) def: "A serine/threonine-protein kinase PLK4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64702-3." [PRO:DNx, UniProtKB:Q64702] comment: Category=organism-sequence. synonym: "mPLK4/iso:m3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q64702-3 is_a: PR:Q64702 ! serine/threonine-protein kinase PLK4 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:O00444-1 name: serine/threonine-protein kinase PLK4 isoform h1 (human) def: "A serine/threonine-protein kinase PLK4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00444-1." [PRO:DNx, UniProtKB:O00444] comment: Category=organism-sequence. synonym: "hPLK4/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O00444-1 is_a: PR:O00444 ! serine/threonine-protein kinase PLK4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:O97143 name: serine/threonine-protein kinase PLK4 (fruit fly) def: "A serine/threonine-protein kinase PLK4 that is encoded in the genome of fruit fly." [OMA:O97143, PANTHER:PTHR24345:SF50, PRO:DNx] comment: Category=organism-gene. synonym: "SAK" RELATED Gene-based [UniProtKB:O97143] synonym: "CG7186" RELATED Gene-based [UniProtKB:O97143] synonym: "fly-PLK4" EXACT PRO-short-label [PRO:DNx] synonym: "PLK-4 (fruit fly)" EXACT [UniProtKB:O97143] synonym: "Polo-like kinase 4 (fruit fly)" EXACT [UniProtKB:O97143] synonym: "serine/threonine-protein kinase SAK (fruit fly)" EXACT [UniProtKB:O97143] xref: UniProtKB:O97143 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000012873 ! serine/threonine-protein kinase PLK4 relationship: has_gene_template FlyBase:FBgn0026371 ! SAK (fruit fly)