[Term]
id: PR:P32871
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (cow)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of cow." [OMA:P32871, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "PIK3CA" RELATED Gene-based [UniProtKB:P32871]
synonym: "cow-PIK3CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PI3Kalpha (cow)" EXACT [UniProtKB:P32871]
synonym: "p110alpha (cow)" EXACT [UniProtKB:P32871]
synonym: "PI3K-alpha (cow)" EXACT [UniProtKB:P32871]
synonym: "PI3-kinase subunit alpha (cow)" EXACT [UniProtKB:P32871]
synonym: "PtdIns-3-kinase subunit alpha (cow)" EXACT [UniProtKB:P32871]
synonym: "PtdIns-3-kinase subunit p110-alpha (cow)" EXACT [UniProtKB:P32871]
synonym: "serine/threonine protein kinase PIK3CA (cow)" EXACT [UniProtKB:P32871]
synonym: "phosphoinositide-3-kinase catalytic alpha polypeptide (cow)" EXACT [UniProtKB:P32871]
synonym: "phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (cow)" EXACT [UniProtKB:P32871]
xref: UniProtKB:P32871
intersection_of: only_in_taxon NCBITaxon:9913 ! Bos taurus
intersection_of: PR:000012719 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
relationship: has_gene_template NCBIGene:282306 ! PIK3CA (cow)

[Term]
id: PR:P42336-1
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1 (human)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hPIK3CA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42336-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039437 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1

[Term]
id: PR:000012719
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
def: "A protein that is a translation product of the human PIK3CA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PIK3CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PI3Kalpha" EXACT []
synonym: "p110alpha" EXACT []
synonym: "PI3K-alpha" EXACT []
synonym: "PI3-kinase subunit alpha" EXACT []
synonym: "PtdIns-3-kinase subunit alpha" EXACT []
synonym: "PtdIns-3-kinase subunit p110-alpha" EXACT []
synonym: "serine/threonine protein kinase PIK3CA" EXACT []
synonym: "phosphoinositide-3-kinase catalytic alpha polypeptide" EXACT []
synonym: "phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha" EXACT []
synonym: "phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha" EXACT []
xref: IUPHARobj:2153
is_a: PR:000000001 ! protein

[Term]
id: PR:Q94125-1
name: phosphatidylinositol 3-kinase age-1 isoform a (worm)
def: "A phosphatidylinositol 3-kinase age-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q94125-1." [PRO:DNx, UniProtKB:Q94125]
comment: Category=organism-sequence.
synonym: "PIK3CA/iso:a (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q94125-1
is_a: PR:Q94125 ! phosphatidylinositol 3-kinase age-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:Q94125-3
name: phosphatidylinositol 3-kinase age-1 isoform b (worm)
def: "A phosphatidylinositol 3-kinase age-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q94125-3." [PRO:DNx, UniProtKB:Q94125]
comment: Category=organism-sequence.
synonym: "PIK3CA/iso:b (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q94125-3
is_a: PR:Q94125 ! phosphatidylinositol 3-kinase age-1 (worm)
relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans

[Term]
id: PR:P42337
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (mouse)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of mouse." [OMA:P42337, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pik3ca" RELATED Gene-based [UniProtKB:P42337]
synonym: "mPIK3CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PI3Kalpha (mouse)" EXACT [UniProtKB:P42337]
synonym: "p110alpha (mouse)" EXACT [UniProtKB:P42337]
synonym: "PI3K-alpha (mouse)" EXACT [UniProtKB:P42337]
synonym: "PI3-kinase subunit alpha (mouse)" EXACT [UniProtKB:P42337]
synonym: "PtdIns-3-kinase subunit alpha (mouse)" EXACT [UniProtKB:P42337]
synonym: "PtdIns-3-kinase subunit p110-alpha (mouse)" EXACT [UniProtKB:P42337]
synonym: "serine/threonine protein kinase PIK3CA (mouse)" EXACT [UniProtKB:P42337]
synonym: "phosphoinositide-3-kinase catalytic alpha polypeptide (mouse)" EXACT [UniProtKB:P42337]
synonym: "phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (mouse)" EXACT [UniProtKB:P42337]
xref: UniProtKB:P42337
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012719 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
relationship: has_gene_template MGI:1206581 ! Pik3ca (mouse)

[Term]
id: PR:P42337-1
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1 (mouse)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mPIK3CA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42337-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039437 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1

[Term]
id: PR:000039437
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform 1
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42336-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "PIK3CA/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000012719 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

[Term]
id: PR:P42336
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (human)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of human." [PRO:DNx, UniProtKB:P42336]
comment: Category=organism-gene.
synonym: "PIK3CA" RELATED Gene-based [UniProtKB:P42336]
synonym: "hPIK3CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PI3Kalpha (human)" EXACT [UniProtKB:P42336]
synonym: "p110alpha (human)" EXACT [UniProtKB:P42336]
synonym: "PI3K-alpha (human)" EXACT [UniProtKB:P42336]
synonym: "PI3-kinase subunit alpha (human)" EXACT [UniProtKB:P42336]
synonym: "PtdIns-3-kinase subunit alpha (human)" EXACT [UniProtKB:P42336]
synonym: "phosphoinositide 3-kinase alpha (human)" EXACT [UniProtKB:P42336]
synonym: "PtdIns-3-kinase subunit p110-alpha (human)" EXACT [UniProtKB:P42336]
synonym: "serine/threonine protein kinase PIK3CA (human)" EXACT [UniProtKB:P42336]
synonym: "phosphoinositide-3-kinase catalytic alpha polypeptide (human)" EXACT [UniProtKB:P42336]
synonym: "phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (human)" EXACT [UniProtKB:P42336]
xref: DTO:03100422
xref: UniProtKB:P42336
xref: Reactome:R-HSA-74787 "PR:P42336 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012719 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
relationship: has_gene_template HGNC:8975 ! PIK3CA (human)

[Term]
id: PR:A0A0G2K344
name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (rat)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of rat." [OMA:A0A0G2K344, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pik3ca" RELATED Gene-based [UniProtKB:A0A0G2K344]
synonym: "rPIK3CA" EXACT PRO-short-label [PRO:DNx]
synonym: "PI3Kalpha (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "p110alpha (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "PI3K-alpha (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "PI3-kinase subunit alpha (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "PtdIns-3-kinase subunit alpha (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "PtdIns-3-kinase subunit p110-alpha (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "serine/threonine protein kinase PIK3CA (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "phosphoinositide-3-kinase catalytic alpha polypeptide (rat)" EXACT [UniProtKB:A0A0G2K344]
synonym: "phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (rat)" EXACT [UniProtKB:A0A0G2K344]
xref: UniProtKB:A0A0G2K344
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012719 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
relationship: has_gene_template RGD:620916 ! Pik3ca (rat)

[Term]
id: PR:Q94125
name: phosphatidylinositol 3-kinase age-1 (worm)
def: "A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of worm." [PRO:DNx]
comment: Category=organism-gene.
synonym: "age-1" RELATED Gene-based [UniProtKB:Q94125]
synonym: "B0334.8" RELATED Gene-based [UniProtKB:Q94125]
synonym: "PIK3CA (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "PI3K age-1 (worm)" EXACT [UniProtKB:Q94125]
synonym: "PI3-kinase age-1 (worm)" EXACT [UniProtKB:Q94125]
synonym: "PtdIns-3-kinase age-1 (worm)" EXACT [UniProtKB:Q94125]
synonym: "aging alteration protein 1 (worm)" EXACT [UniProtKB:Q94125]
xref: UniProtKB:Q94125
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000012719 ! phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
relationship: has_gene_template WormBase:WBGene00000090 ! age-1 (worm)