[Term] id: PR:O88763-1 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 (rat) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rPIK3C3/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O88763-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000041953 ! phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 [Term] id: PR:P22543 name: phosphatidylinositol 3-kinase VPS34 (yeast) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of yeast." [OMA:P22543, PANTHER:PTHR10048:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "VPL7" RELATED Gene-based [UniProtKB:P22543] synonym: "END12" RELATED Gene-based [UniProtKB:P22543] synonym: "PEP15" RELATED Gene-based [UniProtKB:P22543] synonym: "VPS34" RELATED Gene-based [UniProtKB:P22543] synonym: "VPT29" RELATED Gene-based [UniProtKB:P22543] synonym: "YLR240W" RELATED Gene-based [UniProtKB:P22543] synonym: "yPIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "L9672.10" RELATED Gene-based [UniProtKB:P22543] synonym: "PI3K VPS34 (yeast)" EXACT [UniProtKB:P22543] synonym: "PI3-kinase VPS34 (yeast)" EXACT [UniProtKB:P22543] synonym: "PtdIns-3-kinase VPS34 (yeast)" EXACT [UniProtKB:P22543] synonym: "vacuolar protein-targeting protein 29 (yeast)" EXACT [UniProtKB:P22543] synonym: "carboxypeptidase Y-deficient protein 15 (yeast)" EXACT [UniProtKB:P22543] synonym: "vacuolar protein sorting-associated protein 34 (yeast)" EXACT [UniProtKB:P22543] xref: UniProtKB:P22543 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template SGD:S000004230 ! VPS34 (yeast) [Term] id: PR:Q8NEB9-1 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 (human) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hPIK3C3/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8NEB9-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000041953 ! phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 [Term] id: PR:000012718 name: phosphatidylinositol 3-kinase catalytic subunit type 3 def: "A protein that is a translation product of the human PIK3C3 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "VPS34" RELATED Gene-based [] synonym: "PIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K type 3" EXACT [] synonym: "PI3-kinase type 3" EXACT [] synonym: "PtdIns-3-kinase type 3" EXACT [] synonym: "phosphoinositide-3-kinase class 3" EXACT [] synonym: "phosphatidylinositol 3-kinase p100 subunit" EXACT [] xref: IUPHARobj:2152 is_a: PR:000000001 ! protein [Term] id: PR:Q9TXI7 name: phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of worm." [OMA:Q9TXI7, PANTHER:PTHR10048:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "vps-34" RELATED Gene-based [UniProtKB:Q9TXI7] synonym: "B0025.1" RELATED Gene-based [UniProtKB:Q9TXI7] synonym: "let-512" RELATED Gene-based [UniProtKB:Q9TXI7] synonym: "PIK3C3 (worm)" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K type 3 (worm)" EXACT [UniProtKB:Q9TXI7] synonym: "PI3-kinase type 3 (worm)" EXACT [UniProtKB:Q9TXI7] synonym: "phosphoinositide-3-kinase class 3 (worm)" EXACT [UniProtKB:Q9TXI7] xref: UniProtKB:Q9TXI7 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template WormBase:WBGene00006932 ! vps-34 (worm) [Term] id: PR:Q6PF93 name: phosphatidylinositol 3-kinase catalytic subunit type 3 (mouse) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of mouse." [OMA:Q6PF93, PRO:DNx] comment: Category=organism-gene. synonym: "Vps34" RELATED Gene-based [UniProtKB:Q6PF93] synonym: "Pik3c3" RELATED Gene-based [UniProtKB:Q6PF93] synonym: "mPIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K type 3 (mouse)" EXACT [UniProtKB:Q6PF93] synonym: "PI3-kinase type 3 (mouse)" EXACT [UniProtKB:Q6PF93] synonym: "PtdIns-3-kinase type 3 (mouse)" EXACT [UniProtKB:Q6PF93] synonym: "phosphoinositide-3-kinase class 3 (mouse)" EXACT [UniProtKB:Q6PF93] xref: UniProtKB:Q6PF93 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template MGI:2445019 ! Pik3c3 (mouse) [Term] id: PR:Q6PF93-2 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform m2 (mouse) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PF93-2." [PRO:DNx, UniProtKB:Q6PF93] comment: Category=organism-sequence. synonym: "mPIK3C3/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6PF93-2 is_a: PR:Q6PF93 ! phosphatidylinositol 3-kinase catalytic subunit type 3 (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q6PF93-1 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 (mouse) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mPIK3C3/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6PF93-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000041953 ! phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 [Term] id: PR:P50520 name: phosphatidylinositol 3-kinase vps34 (Schizosaccharomyces pombe 972h-) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P50520, PANTHER:PTHR10048:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "vps34" RELATED Gene-based [UniProtKB:P50520] synonym: "SPAC458.05" RELATED Gene-based [UniProtKB:P50520] synonym: "Spom972h-PIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K vps34 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P50520] synonym: "PI3-kinase vps34 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P50520] synonym: "PtdIns-3-kinase vps34 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P50520] synonym: "vacuolar protein sorting-associated protein 34 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P50520] xref: UniProtKB:P50520 intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h- intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template PomBase:SPAC458.05 ! vps34 (Schizosaccharomyces pombe) [Term] id: PR:000041953 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1 def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NEB9-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "PIK3C3/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 [Term] id: PR:Q9TXI7-2 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform b (worm) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9TXI7-2." [PRO:DNx, UniProtKB:Q9TXI7] comment: Category=organism-sequence. synonym: "PIK3C3/iso:b (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9TXI7-2 is_a: PR:Q9TXI7 ! phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:Q9TXI7-3 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform c (worm) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9TXI7-3." [PRO:DNx, UniProtKB:Q9TXI7] comment: Category=organism-sequence. synonym: "PIK3C3/iso:c (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9TXI7-3 is_a: PR:Q9TXI7 ! phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:Q8NEB9 name: phosphatidylinositol 3-kinase catalytic subunit type 3 (human) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-gene. synonym: "VPS34" RELATED Gene-based [UniProtKB:Q8NEB9] synonym: "PIK3C3" RELATED Gene-based [UniProtKB:Q8NEB9] synonym: "hVps34" EXACT [UniProtKB:Q8NEB9] synonym: "hPIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K type 3 (human)" EXACT [UniProtKB:Q8NEB9] synonym: "PI3-kinase type 3 (human)" EXACT [UniProtKB:Q8NEB9] synonym: "PtdIns-3-kinase type 3 (human)" EXACT [UniProtKB:Q8NEB9] synonym: "phosphoinositide-3-kinase class 3 (human)" EXACT [UniProtKB:Q8NEB9] synonym: "phosphatidylinositol 3-kinase p100 subunit (human)" EXACT [UniProtKB:Q8NEB9] xref: UniProtKB:Q8NEB9 xref: Reactome:R-HSA-188011 "PR:Q8NEB9 located_in GO:0005829" xref: Reactome:R-HSA-6798182 "PR:Q8NEB9 located_in GO:0030670" xref: DTO:03100421 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template HGNC:8974 ! PIK3C3 (human) [Term] id: PR:Q9TXI7-1 name: phosphatidylinositol 3-kinase catalytic subunit type 3 isoform a (worm) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9TXI7-1." [PRO:DNx, UniProtKB:Q9TXI7] comment: Category=organism-sequence. synonym: "PIK3C3/iso:a (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9TXI7-1 is_a: PR:Q9TXI7 ! phosphatidylinositol 3-kinase catalytic subunit type 3 (worm) relationship: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans [Term] id: PR:P42339 name: phosphatidylinositol 3-kinase VPS34 (Arabidopsis thaliana) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of Arabidopsis thaliana." [OMA:P42339, PANTHER:PTHR10048:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "VPS34" RELATED Gene-based [UniProtKB:P42339] synonym: "F8A5.4" RELATED Gene-based [UniProtKB:P42339] synonym: "AtVPS34" EXACT [UniProtKB:P42339] synonym: "At-PIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "At1g60490" RELATED Gene-based [UniProtKB:P42339] synonym: "PI3K VPS34 (Arabidopsis thaliana)" EXACT [UniProtKB:P42339] synonym: "PI3-kinase VPS34 (Arabidopsis thaliana)" EXACT [UniProtKB:P42339] synonym: "PtdIns-3-kinase VSP34 (Arabidopsis thaliana)" EXACT [UniProtKB:P42339] xref: UniProtKB:P42339 intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template Araport:AT1G60490 ! VPS34 (Arabidopsis thaliana) [Term] id: PR:P54676 name: phosphatidylinositol 3-kinase VPS34-like (Dictyostelium discoideum) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of Dictyostelium discoideum." [OMA:P54676, PANTHER:PTHR10048:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "pik5" RELATED Gene-based [UniProtKB:P54676] synonym: "pikE" RELATED Gene-based [UniProtKB:P54676] synonym: "DDB_G0289601" RELATED Gene-based [UniProtKB:P54676] synonym: "Dicty-PIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K (Dictyostelium discoideum)" BROAD [UniProtKB:P54676] synonym: "PI3-kinase (Dictyostelium discoideum)" BROAD [UniProtKB:P54676] synonym: "PtdIns-3-kinase (Dictyostelium discoideum)" BROAD [UniProtKB:P54676] xref: UniProtKB:P54676 intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template dictyBase:DDB_G0289601 ! pikE (Dictyostelium discoideum) [Term] id: PR:O88763 name: phosphatidylinositol 3-kinase catalytic subunit type 3 (rat) def: "A phosphatidylinositol 3-kinase catalytic subunit type 3 that is encoded in the genome of rat." [OMA:O88763, PANTHER:PTHR10048:SF7, PRO:DNx] comment: Category=organism-gene. synonym: "Vps34" RELATED Gene-based [UniProtKB:O88763] synonym: "Pik3c3" RELATED Gene-based [UniProtKB:O88763] synonym: "rPIK3C3" EXACT PRO-short-label [PRO:DNx] synonym: "PI3K type 3 (rat)" EXACT [UniProtKB:O88763] synonym: "PI3-kinase type 3 (rat)" EXACT [UniProtKB:O88763] synonym: "PtdIns-3-kinase type 3 (rat)" EXACT [UniProtKB:O88763] synonym: "phosphoinositide-3-kinase class 3 (rat)" EXACT [UniProtKB:O88763] xref: UniProtKB:O88763 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000012718 ! phosphatidylinositol 3-kinase catalytic subunit type 3 relationship: has_gene_template RGD:620899 ! Pik3c3 (rat)