[Term]
id: PR:000012671
name: paired mesoderm homeobox protein 2A
def: "A protein that is a translation product of the human PHOX2A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ARIX" RELATED Gene-based []
synonym: "Pmx2" RELATED Gene-based []
synonym: "PMX2A" RELATED Gene-based []
synonym: "Phox2" RELATED Gene-based []
synonym: "PHOX2A" EXACT PRO-short-label [PRO:DNx]
synonym: "paired-like homeobox 2A" EXACT []
synonym: "ARIX1 homeodomain protein" EXACT []
synonym: "PHOX2A homeodomain protein" EXACT []
synonym: "aristaless homeobox protein homolog" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000045570
name: paired mesoderm homeobox protein 2A phosphorylated 1 (human)
def: "A paired mesoderm homeobox protein 2A (human) that has been phosphorylated at Ser-153. UniProtKB:O14813, Ser-153, MOD:00046." [PMID:19564421, iPTMnet:O14813]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19564421). Status=unreviewed.
synonym: "hPHOX2A/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14813, Ser-153, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:O14813 ! paired mesoderm homeobox protein 2A (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q62066
name: paired mesoderm homeobox protein 2A (mouse)
def: "A paired mesoderm homeobox protein 2A that is encoded in the genome of mouse." [OMA:Q62066, PRO:DNx]
comment: Category=organism-gene.
synonym: "Arix" RELATED Gene-based [UniProtKB:Q62066]
synonym: "Pmx2" RELATED Gene-based [UniProtKB:Q62066]
synonym: "Phox2" RELATED Gene-based [UniProtKB:Q62066]
synonym: "Pmx2a" RELATED Gene-based [UniProtKB:Q62066]
synonym: "Phox2a" RELATED Gene-based [UniProtKB:Q62066]
synonym: "mPHOX2A" EXACT PRO-short-label [PRO:DNx]
synonym: "paired-like homeobox 2A (mouse)" EXACT [UniProtKB:Q62066]
synonym: "PHOX2A homeodomain protein (mouse)" EXACT [UniProtKB:Q62066]
synonym: "aristaless homeobox protein homolog (mouse)" EXACT [UniProtKB:Q62066]
xref: UniProtKB:Q62066
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012671 ! paired mesoderm homeobox protein 2A
relationship: has_gene_template MGI:106633 ! Phox2a (mouse)

[Term]
id: PR:O14813
name: paired mesoderm homeobox protein 2A (human)
def: "A paired mesoderm homeobox protein 2A that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14813]
comment: Category=organism-gene.
synonym: "ARIX" RELATED Gene-based [UniProtKB:O14813]
synonym: "PMX2A" RELATED Gene-based [UniProtKB:O14813]
synonym: "PHOX2A" RELATED Gene-based [UniProtKB:O14813]
synonym: "hPHOX2A" EXACT PRO-short-label [PRO:DNx]
synonym: "paired-like homeobox 2A (human)" EXACT [UniProtKB:O14813]
synonym: "ARIX1 homeodomain protein (human)" EXACT [UniProtKB:O14813]
synonym: "aristaless homeobox protein homolog (human)" EXACT [UniProtKB:O14813]
xref: UniProtKB:O14813
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012671 ! paired mesoderm homeobox protein 2A
relationship: has_gene_template HGNC:691 ! PHOX2A (human)

[Term]
id: PR:000050551
name: paired mesoderm homeobox protein 2A monoubiquitinated 1 (human)
def: "A paired mesoderm homeobox protein 2A (human) that has been monoubiquitinated at the residue equivalent to Lys-178 of the amino acid sequence represented by UniProtKB:O14813. UniProtKB:O14813, Lys-178, PR:000044771." [PMID:32094113, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:32094113).
synonym: "hPHOX2A/MonoUbiq:1" EXACT PRO-short-label [PRO:KER]
synonym: "UniProtKB:O14813, Lys-178, PR:000044771" EXACT PRO-proteoform-std [PRO:KER]
synonym: "UniProtKB:O14813-1, Lys-178, PR:000044771" NARROW PRO-proteoform-std [PRO:DAN]
is_a: PR:O14813 ! paired mesoderm homeobox protein 2A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_part PR:000044771 ! monoubiquitinylated lysine

[Term]
id: PR:000050550
name: paired mesoderm homeobox protein 2A monoubiquitinated 1 (mouse)
def: "A paired mesoderm homeobox protein 2A (mouse) that has been monoubiquitinated at the residue equivalent to Lys-178 of the amino acid sequence represented by UniProtKB:Q62066. UniProtKB:Q62066, Lys-178, PR:000044771." [PMID:32094113, PRO:LN]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:32094113).
synonym: "mPHOX2A/MonoUbiq:1" EXACT PRO-short-label [PRO:KER]
synonym: "UniProtKB:Q62066, Lys-178, PR:000044771" EXACT PRO-proteoform-std [PRO:KER]
synonym: "UniProtKB:Q62066-1, Lys-178, PR:000044771" NARROW PRO-proteoform-std [PRO:DAN]
is_a: PR:Q62066 ! paired mesoderm homeobox protein 2A (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus
relationship: has_part PR:000044771 ! monoubiquitinylated lysine

[Term]
id: PR:Q62782
name: paired mesoderm homeobox protein 2A (rat)
def: "A paired mesoderm homeobox protein 2A that is encoded in the genome of rat." [OMA:Q62782, PANTHER:PTHR24329:SF103, PRO:DNx]
comment: Category=organism-gene.
synonym: "Arix" RELATED Gene-based [UniProtKB:Q62782]
synonym: "Pmx2a" RELATED Gene-based [UniProtKB:Q62782]
synonym: "Phox2a" RELATED Gene-based [UniProtKB:Q62782]
synonym: "rPHOX2A" EXACT PRO-short-label [PRO:DNx]
synonym: "paired-like homeobox 2A (rat)" EXACT [UniProtKB:Q62782]
synonym: "ARIX1 homeodomain protein (rat)" EXACT [UniProtKB:Q62782]
synonym: "aristaless homeobox protein homolog (rat)" EXACT [UniProtKB:Q62782]
xref: UniProtKB:Q62782
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012671 ! paired mesoderm homeobox protein 2A
relationship: has_gene_template RGD:621323 ! Phox2a (rat)