[Term]
id: PR:P26367-2
name: paired box protein Pax-6 isoform 2 (human)
def: "A paired box protein Pax-6 isoform 2 that is encoded in the genome of human." [PMID:10954416, PMID:7958875, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hPAX6/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P26367-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037282 ! paired box protein Pax-6 isoform 2

[Term]
id: PR:P26367-3
name: paired box protein Pax-6 isoform h3 (human)
def: "A paired box protein Pax-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26367-3." [PRO:DNx, UniProtKB:P26367]
comment: Category=organism-sequence.
synonym: "hPAX6/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "paired box protein Pax-6 isoform Pax6-5A,6* (human)" EXACT [UniProtKB:P26367]
xref: UniProtKB:P26367-3
is_a: PR:P26367 ! paired box protein Pax-6 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P26367-1
name: paired box protein Pax-6 isoform 1 (human)
def: "A paired box protein Pax-6 isoform 1 that is encoded in the genome of human." [PMID:7958875, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hPAX6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P26367-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037280 ! paired box protein Pax-6 isoform 1

[Term]
id: PR:P26367
name: paired box protein Pax-6 (human)
def: "A paired box protein Pax-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P26367]
comment: Category=organism-gene.
synonym: "AN2" RELATED Gene-based [UniProtKB:P26367]
synonym: "PAX6" RELATED Gene-based [UniProtKB:P26367]
synonym: "hPAX6" EXACT PRO-short-label [PRO:DNx]
synonym: "oculorhombin (human)" EXACT [UniProtKB:P26367]
synonym: "aniridia type II protein (human)" EXACT [UniProtKB:P26367]
xref: Reactome:R-HSA-3009044 "PR:P26367 located_in GO:0005654"
xref: UniProtKB:P26367
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000012318 ! paired box protein Pax-6
relationship: has_gene_template HGNC:8620 ! PAX6 (human)

[Term]
id: PR:P63015-1
name: paired box protein Pax-6 isoform 1 (mouse)
def: "A paired box protein Pax-6 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PMID:21084637, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mPAX6/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "Pax-6 p46 (mouse)" EXACT []
xref: UniProtKB:P63015-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037280 ! paired box protein Pax-6 isoform 1

[Term]
id: PR:P63015-3
name: paired box protein Pax-6 isoform 3 (mouse)
def: "A paired box protein Pax-6 isoform 3 that is encoded in the genome of mouse." [PMID:15489334, PMID:21084637, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mPAX6/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "Pax-6 p32/33 (mouse)" EXACT []
xref: UniProtKB:P63015-3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037284 ! paired box protein Pax-6 isoform 3

[Term]
id: PR:P63015-2
name: paired box protein Pax-6 isoform 2 (mouse)
def: "A paired box protein Pax-6 isoform 2 that is encoded in the genome of mouse." [PMID:15489334, PMID:21084637, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mPAX6/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "Pax-6 p48 (mouse)" EXACT []
xref: UniProtKB:P63015-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037282 ! paired box protein Pax-6 isoform 2

[Term]
id: PR:P63016-2
name: paired box protein Pax-6 isoform 2 (rat)
def: "A paired box protein Pax-6 isoform 2 that is encoded in the genome of rat." [PMID:24952136, PRO:CNA]
comment: Category=organism-sequence.
synonym: "rPAX6/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63016-2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000037282 ! paired box protein Pax-6 isoform 2

[Term]
id: PR:P63016-1
name: paired box protein Pax-6 isoform 1 (rat)
def: "A paired box protein Pax-6 isoform 1 that is encoded in the genome of rat." [PMID:15489334, PMID:24952136, PRO:CNA]
comment: Category=organism-sequence.
synonym: "rPAX6/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63016-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000037280 ! paired box protein Pax-6 isoform 1

[Term]
id: PR:P26630
name: paired box protein Pax-6 (zebrafish)
def: "A paired box protein Pax-6 that is encoded in the genome of zebrafish." [OMA:P26630, PRO:DNx]
comment: Category=organism-gene.
synonym: "pax6a" RELATED Gene-based [UniProtKB:P26630]
synonym: "z-PAX6" EXACT PRO-short-label [PRO:DNx]
synonym: "paxzf-a" RELATED Gene-based [UniProtKB:P26630]
synonym: "pax[zf-a]" RELATED Gene-based [UniProtKB:P26630]
synonym: "si:dkeyp-46c10.1" RELATED Gene-based [UniProtKB:P26630]
synonym: "Pax[Zf-a] (zebrafish)" EXACT [UniProtKB:P26630]
xref: UniProtKB:P26630
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000012318 ! paired box protein Pax-6
relationship: has_gene_template ZFIN:ZDB-GENE-990415-200 ! pax6a (zebrafish)

[Term]
id: PR:O18381-2
name: paired box protein Pax-6 isoform Embryonic (fruit fly)
def: "A paired box protein Pax-6 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O18381-2." [PRO:DNx, UniProtKB:O18381]
comment: Category=organism-sequence.
synonym: "fly-PAX6/iso:Embryonic" EXACT PRO-short-label [PRO:DNx]
synonym: "paired box protein Pax-6 isoform A (fruit fly)" EXACT [UniProtKB:O18381]
xref: UniProtKB:O18381-2
is_a: PR:O18381 ! paired box protein Pax-6 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:O18381-3
name: paired box protein Pax-6 isoform B (fruit fly)
def: "A paired box protein Pax-6 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O18381-3." [PRO:DNx, UniProtKB:O18381]
comment: Category=organism-sequence.
synonym: "fly-PAX6/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O18381-3
is_a: PR:O18381 ! paired box protein Pax-6 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:O18381-1
name: paired box protein Pax-6 isoform Larval (fruit fly)
def: "A paired box protein Pax-6 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O18381-1." [PRO:DNx, UniProtKB:O18381]
comment: Category=organism-sequence.
synonym: "fly-PAX6/iso:Larval" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O18381-1
is_a: PR:O18381 ! paired box protein Pax-6 (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P26630-2
name: paired box protein Pax-6 isoform Long (zebrafish)
def: "A paired box protein Pax-6 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26630-2." [PRO:DNx, UniProtKB:P26630]
comment: Category=organism-sequence.
synonym: "z-PAX6/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P26630-2
is_a: PR:P26630 ! paired box protein Pax-6 (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:P26630-1
name: paired box protein Pax-6 isoform Short (zebrafish)
def: "A paired box protein Pax-6 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26630-1." [PRO:DNx, UniProtKB:P26630]
comment: Category=organism-sequence.
synonym: "z-PAX6/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P26630-1
is_a: PR:P26630 ! paired box protein Pax-6 (zebrafish)
relationship: only_in_taxon NCBITaxon:7955 ! Danio rerio

[Term]
id: PR:000037280
name: paired box protein Pax-6 isoform 1
def: "A paired box protein Pax-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63015-1 or a 1:1 ortholog thereof." [PMID:16141072, PMID:21084637, PRO:HJD]
comment: Category=sequence.
synonym: "PAX6/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000012318 ! paired box protein Pax-6

[Term]
id: PR:000037282
name: paired box protein Pax-6 isoform 2
def: "A paired box protein Pax-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63015-2 or a 1:1 ortholog thereof." [PMID:15489334, PMID:21084637, PRO:HJD]
comment: Category=sequence.
synonym: "PAX6/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "Pax-6 isoform 5a" EXACT []
is_a: PR:000012318 ! paired box protein Pax-6

[Term]
id: PR:O18381
name: paired box protein Pax-6 (fruit fly)
def: "A paired box protein Pax-6 that is encoded in the genome of fruit fly." [PANTHER:PTHR24329:SF73, PRO:DNx]
comment: Category=organism-gene.
synonym: "ey" RELATED Gene-based [UniProtKB:O18381]
synonym: "pax6" RELATED Gene-based [UniProtKB:O18381]
synonym: "CG1464" RELATED Gene-based [UniProtKB:O18381]
synonym: "fly-PAX6" EXACT PRO-short-label [PRO:DNx]
synonym: "protein eyeless (fruit fly)" EXACT [UniProtKB:O18381]
xref: UniProtKB:O18381
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000012318 ! paired box protein Pax-6
relationship: has_gene_template FlyBase:FBgn0005558 ! ey (fruit fly)

[Term]
id: PR:000037284
name: paired box protein Pax-6 isoform 3
def: "A paired box protein Pax-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63015-3 or a 1:1 ortholog thereof." [PMID:11042159, PMID:21084637, PRO:HJD]
comment: Category=sequence.
synonym: "PAX6/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000012318 ! paired box protein Pax-6

[Term]
id: PR:000037286
name: paired box protein Pax-6 isoform 3 sumoylated 1
def: "A paired box protein Pax-6 isoform 3 that has been sumoylated by SUMO 1 on a Lys residue within the DNA binding domain. Example: UniProtKB:P63015-3, Lys-91, MOD:01149." [PMID:21084637, PRO:HJD]
comment: Category=modification.
synonym: "PAX6/iso:3/Sumo:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000037284 ! paired box protein Pax-6 isoform 3
relationship: has_part MOD:01149 ! sumoylated lysine

[Term]
id: PR:000037287
name: paired box protein Pax-6 isoform 3 sumoylated 1 (mouse)
def: "A paired box protein Pax-6 isoform 3 sumoylated 1 in mouse. UniProtKB:P63015-3, Lys-91, MOD:01149." [PMID:21084637, PRO:HJD]
comment: Category=organism-modification.
synonym: "mPAX6/iso:3/Sumo:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63015-3, Lys-91, MOD:01149" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037286 ! paired box protein Pax-6 isoform 3 sumoylated 1
relationship: has_part MOD:01149 ! sumoylated lysine

[Term]
id: PR:000037288
name: paired box protein Pax-6 isoform 3 unsumoylated 1
def: "A paired box protein Pax-6 isoform 3 that lacks a sumo modification on a Lys residue within the DNA binding domain. Example: UniProtKB:P63015-3, Lys-91, PR:000026291." [PMID:21084637, PRO:DAN, PRO:HJD]
comment: Category=modification.
synonym: "PAX6/iso:3/UnSumo:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000037284 ! paired box protein Pax-6 isoform 3

[Term]
id: PR:000037289
name: paired box protein Pax-6 isoform 3 unsumoylated 1 (mouse)
def: "A paired box protein Pax-6 isoform 3 unsumoylated 1 in mouse. This lacks the sumoylation on the lysine corresponding to position 91 of the amino acid sequence represented by UniProtKB:P63015-3. UniProtKB:P63015-3, Lys-91, PR:000026291." [PMID:21084637, PRO:HJD]
comment: Category=organism-modification.
synonym: "mPAX6/iso:3/UnSumo:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P63015-3, Lys-91, PR:000026291" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000037288 ! paired box protein Pax-6 isoform 3 unsumoylated 1

[Term]
id: PR:000012318
name: paired box protein Pax-6
def: "A paired box protein PAX group IV that is a translation product of the human PAX6 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AN2" RELATED Gene-based []
synonym: "Sey" RELATED Gene-based []
synonym: "PAX6" EXACT PRO-short-label [PRO:DNx]
synonym: "Pax-6" RELATED Gene-based []
synonym: "oculorhombin" EXACT []
synonym: "aniridia type II protein" EXACT []
is_a: PR:000037798 ! paired box protein PAX group IV

[Term]
id: PR:P63015
name: paired box protein Pax-6 (mouse)
def: "A paired box protein Pax-6 that is encoded in the genome of mouse." [OMA:P63015, PRO:DNx]
comment: Category=organism-gene.
synonym: "Sey" RELATED Gene-based [UniProtKB:P63015]
synonym: "Pax6" RELATED Gene-based [UniProtKB:P63015]
synonym: "Pax-6" RELATED Gene-based [UniProtKB:P63015]
synonym: "mPAX6" EXACT PRO-short-label [PRO:DNx]
synonym: "oculorhombin (mouse)" EXACT [UniProtKB:P63015]
xref: UniProtKB:P63015
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000012318 ! paired box protein Pax-6
relationship: has_gene_template MGI:97490 ! Pax6 (mouse)

[Term]
id: PR:P63016
name: paired box protein Pax-6 (rat)
def: "A paired box protein Pax-6 that is encoded in the genome of rat." [OMA:P63016, PANTHER:PTHR24329:SF73, PRO:DNx]
comment: Category=organism-gene.
synonym: "Sey" RELATED Gene-based [UniProtKB:P63016]
synonym: "Pax6" RELATED Gene-based [UniProtKB:P63016]
synonym: "Pax-6" RELATED Gene-based [UniProtKB:P63016]
synonym: "rPAX6" EXACT PRO-short-label [PRO:DNx]
synonym: "oculorhombin (rat)" EXACT [UniProtKB:P63016]
xref: UniProtKB:P63016
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000012318 ! paired box protein Pax-6
relationship: has_gene_template RGD:3258 ! Pax6 (rat)