[Term]
id: PR:P70512
name: hepatocyte nuclear factor 6 (rat)
def: "A hepatocyte nuclear factor 6 that is encoded in the genome of rat." [PANTHER:PTHR14057:SF9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hnf6" RELATED Gene-based [UniProtKB:P70512]
synonym: "Hnf6a" RELATED Gene-based [UniProtKB:P70512]
synonym: "Onecut1" RELATED Gene-based [UniProtKB:P70512]
synonym: "rONECUT1" EXACT PRO-short-label [PRO:DNx]
synonym: "HNF-6 (rat)" EXACT [UniProtKB:P70512]
synonym: "one cut homeobox 1 (rat)" EXACT [UniProtKB:P70512]
synonym: "one cut domain family member 1 (rat)" EXACT [UniProtKB:P70512]
xref: UniProtKB:P70512
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000011639 ! hepatocyte nuclear factor 6
relationship: has_gene_template RGD:2811 ! Onecut1 (rat)

[Term]
id: PR:O08755
name: hepatocyte nuclear factor 6 (mouse)
def: "A hepatocyte nuclear factor 6 that is encoded in the genome of mouse." [OMA:O08755, PRO:DNx]
comment: Category=organism-gene.
synonym: "Hnf6" RELATED Gene-based [UniProtKB:O08755]
synonym: "Hnf6a" RELATED Gene-based [UniProtKB:O08755]
synonym: "Onecut1" RELATED Gene-based [UniProtKB:O08755]
synonym: "mONECUT1" EXACT PRO-short-label [PRO:DNx]
synonym: "HNF-6 (mouse)" EXACT [UniProtKB:O08755]
synonym: "one cut homeobox 1 (mouse)" EXACT [UniProtKB:O08755]
synonym: "one cut domain family member 1 (mouse)" EXACT [UniProtKB:O08755]
xref: UniProtKB:O08755
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011639 ! hepatocyte nuclear factor 6
relationship: has_gene_template MGI:1196423 ! Onecut1 (mouse)

[Term]
id: PR:Q9UBC0-1
name: hepatocyte nuclear factor 6 isoform 1 (human)
def: "A hepatocyte nuclear factor 6 isoform 1 that is encoded in the genome of human." [PRO:PD]
comment: Category=organism-sequence.
synonym: "hONECUT1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9UBC0-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028755 ! hepatocyte nuclear factor 6 isoform 1

[Term]
id: PR:000011639
name: hepatocyte nuclear factor 6
def: "A protein that is a translation product of the human ONECUT1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HNF6" RELATED Gene-based []
synonym: "HNF-6" EXACT []
synonym: "HNF6A" RELATED Gene-based []
synonym: "ONECUT1" EXACT PRO-short-label [PRO:DNx]
synonym: "one cut homeobox 1" EXACT []
synonym: "one cut domain family member 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000028757
name: hepatocyte nuclear factor 6 isoform 1 acetylated 1
def: "A hepatocyte nuclear factor 6 isoform 1 that has been acetylated on a Lys residue located at the HNF6 Cut domain (Pfam:PF02376). Example: UniProtKB:Q9UBC0-1, Lys-339, MOD:00064." [PMID:15304484, PRO:PD]
comment: Category=modification.
synonym: "ONECUT1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000028755 ! hepatocyte nuclear factor 6 isoform 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000028755
name: hepatocyte nuclear factor 6 isoform 1
def: "A hepatocyte nuclear factor 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBC0-1 or a 1:1 ortholog thereof." [PMID:15304484, PRO:PD]
comment: Category=sequence.
synonym: "ONECUT1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000011639 ! hepatocyte nuclear factor 6

[Term]
id: PR:P70512-1
name: hepatocyte nuclear factor 6 isoform Alpha (rat)
def: "A hepatocyte nuclear factor 6 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70512-1." [PRO:DNx, UniProtKB:P70512]
comment: Category=organism-sequence.
synonym: "rONECUT1/iso:Alpha" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P70512-1
is_a: PR:P70512 ! hepatocyte nuclear factor 6 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q9UBC0
name: hepatocyte nuclear factor 6 (human)
def: "A hepatocyte nuclear factor 6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9UBC0]
comment: Category=organism-gene.
synonym: "HNF6" RELATED Gene-based [UniProtKB:Q9UBC0]
synonym: "HNF6A" RELATED Gene-based [UniProtKB:Q9UBC0]
synonym: "ONECUT1" RELATED Gene-based [UniProtKB:Q9UBC0]
synonym: "hONECUT1" EXACT PRO-short-label [PRO:DNx]
synonym: "HNF-6 (human)" EXACT [UniProtKB:Q9UBC0]
synonym: "one cut homeobox 1 (human)" EXACT [UniProtKB:Q9UBC0]
synonym: "one cut domain family member 1 (human)" EXACT [UniProtKB:Q9UBC0]
xref: UniProtKB:Q9UBC0
xref: Reactome:R-HSA-210782 "PR:Q9UBC0 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011639 ! hepatocyte nuclear factor 6
relationship: has_gene_template HGNC:8138 ! ONECUT1 (human)

[Term]
id: PR:P70512-2
name: hepatocyte nuclear factor 6 isoform Beta (rat)
def: "A hepatocyte nuclear factor 6 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70512-2." [PRO:DNx, UniProtKB:P70512]
comment: Category=organism-sequence.
synonym: "rONECUT1/iso:Beta" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P70512-2
is_a: PR:P70512 ! hepatocyte nuclear factor 6 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000028758
name: hepatocyte nuclear factor 6 isoform 1 acetylated 1 (human)
def: "A hepatocyte nuclear factor 6 isoform 1 acetylated 1 in human. Acetylation leads to enhanced protein stability and transcriptional activity. UniProtKB:Q9UBC0-1, Lys-339, MOD:00064." [PMID:15304484, PRO:PD]
comment: Category=organism-modification. Acetylase=("CREBBP"; PR:Q92793).
synonym: "hONECUT1/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UBC0-1, Lys-339, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028757 ! hepatocyte nuclear factor 6 isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine