[Term]
id: PR:000011612
name: 2-oxoglutarate dehydrogenase, mitochondrial
def: "A protein that is a translation product of the human OGDH gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "OGDH" EXACT PRO-short-label [PRO:DNx]
synonym: "OGDC-E1" EXACT []
synonym: "Kiaa4192" RELATED Gene-based []
synonym: "alpha-ketoglutarate dehydrogenase" BROAD [PRO:DNx]
synonym: "2-oxoglutarate dehydrogenase complex component E1" EXACT []
synonym: "2-oxoglutarate dehydrogenase E1 component, mitochondrial" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q02218-1
name: 2-oxoglutarate dehydrogenase, mitochondrial isoform 1 (human)
def: "A 2-oxoglutarate dehydrogenase, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "hOGDH/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02218-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026830 ! 2-oxoglutarate dehydrogenase, mitochondrial isoform 1

[Term]
id: PR:Q02218-2
name: 2-oxoglutarate dehydrogenase, mitochondrial isoform h2 (human)
def: "A 2-oxoglutarate dehydrogenase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02218-2." [PRO:DNx, UniProtKB:Q02218]
comment: Category=organism-sequence.
synonym: "hOGDH/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02218-2
is_a: PR:Q02218 ! 2-oxoglutarate dehydrogenase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02218-3
name: 2-oxoglutarate dehydrogenase, mitochondrial isoform h3 (human)
def: "A 2-oxoglutarate dehydrogenase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02218-3." [PRO:DNx, UniProtKB:Q02218]
comment: Category=organism-sequence.
synonym: "hOGDH/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02218-3
is_a: PR:Q02218 ! 2-oxoglutarate dehydrogenase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02218
name: 2-oxoglutarate dehydrogenase, mitochondrial (human)
def: "A 2-oxoglutarate dehydrogenase, mitochondrial that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q02218]
comment: Category=organism-gene.
synonym: "OGDH" RELATED Gene-based [UniProtKB:Q02218]
synonym: "hOGDH" EXACT PRO-short-label [PRO:DNx]
synonym: "OGDC-E1 (human)" EXACT [UniProtKB:Q02218]
synonym: "alpha-ketoglutarate dehydrogenase (human)" EXACT [UniProtKB:Q02218]
synonym: "2-oxoglutarate dehydrogenase complex component E1 (human)" EXACT [UniProtKB:Q02218]
xref: UniProtKB:Q02218
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011612 ! 2-oxoglutarate dehydrogenase, mitochondrial
relationship: has_gene_template HGNC:8124 ! OGDH (human)

[Term]
id: PR:000048663
name: 2-oxoglutarate dehydrogenase, mitochondrial, transit peptide removed form (human)
def: "A 2-oxoglutarate dehydrogenase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:Q02218, 41-1023." [PRO:DNx, Reactome:R-HSA-69981]
comment: Category=organism-modification.
synonym: "PRO_0000020432" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hOGDH/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q02218, 41-1023" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-69981 "PR:000048663 located_in GO:0005759"
intersection_of: PR:Q02218 ! 2-oxoglutarate dehydrogenase, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens