[Term]
id: PR:O75469-6
name: nuclear receptor subfamily 1 group I member 2 isoform h2C (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-6." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h2C" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PRR2-C (human)" EXACT [UniProtKB:O75469]
xref: UniProtKB:O75469-6
xref: Reactome:R-HSA-3196160 "PR:O75469-6 located_in GO:0005654"
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75469-7
name: nuclear receptor subfamily 1 group I member 2 isoform h3 (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-7." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O75469-7
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75469-4
name: nuclear receptor subfamily 1 group I member 2 isoform h2A (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-4." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h2A" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform 2 (human)" EXACT [UniProtKB:O75469]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PRR2-A (human)" EXACT [UniProtKB:O75469]
xref: UniProtKB:O75469-4
xref: Reactome:R-HSA-3196184 "PR:O75469-4 located_in GO:0005654"
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75469-5
name: nuclear receptor subfamily 1 group I member 2 isoform h2B (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-5." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h2B" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PRR2-B (human)" EXACT [UniProtKB:O75469]
xref: UniProtKB:O75469-5
xref: Reactome:R-HSA-3196166 "PR:O75469-5 located_in GO:0005654"
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75469-2
name: nuclear receptor subfamily 1 group I member 2 isoform h1B (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-2." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h1B" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PRR1-B (human)" EXACT [UniProtKB:O75469]
xref: UniProtKB:O75469-2
xref: Reactome:R-HSA-3196181 "PR:O75469-2 located_in GO:0005654"
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O54915-2
name: nuclear receptor subfamily 1 group I member 2 isoform m2 (mouse)
def: "A nuclear receptor subfamily 1 group I member 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54915-2." [PRO:DNx, UniProtKB:O54915]
comment: Category=organism-sequence.
synonym: "mNR1I2/iso:m2" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PXR.2 (mouse)" EXACT [UniProtKB:O54915]
xref: UniProtKB:O54915-2
is_a: PR:O54915 ! nuclear receptor subfamily 1 group I member 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O54915-1
name: nuclear receptor subfamily 1 group I member 2 isoform 1 (mouse)
def: "A nuclear receptor subfamily 1 group I member 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mNR1I2/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PXR.1 (mouse)" EXACT [UniProtKB:O54915]
xref: UniProtKB:O54915-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038211 ! nuclear receptor subfamily 1 group I member 2 isoform 1

[Term]
id: PR:O75469-1
name: nuclear receptor subfamily 1 group I member 2 isoform h1A (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-1." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h1A" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform 1 (human)" EXACT [UniProtKB:O75469]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PRR1-A (human)" EXACT [UniProtKB:O75469]
xref: UniProtKB:O75469-1
xref: Reactome:R-HSA-3008636 "PR:O75469-1 located_in GO:0005654"
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O75469
name: nuclear receptor subfamily 1 group I member 2 (human)
def: "A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-gene.
synonym: "PXR" RELATED Gene-based [UniProtKB:O75469]
synonym: "NR1I2" RELATED Gene-based [UniProtKB:O75469]
synonym: "hNR1I2" EXACT PRO-short-label [PRO:DNx]
synonym: "SXR (human)" EXACT [UniProtKB:O75469]
synonym: "pregnane X receptor (human)" EXACT [UniProtKB:O75469]
synonym: "orphan nuclear receptor PXR (human)" EXACT [UniProtKB:O75469]
synonym: "orphan nuclear receptor PAR1 (human)" EXACT [UniProtKB:O75469]
synonym: "steroid and xenobiotic receptor (human)" EXACT [UniProtKB:O75469]
xref: Reactome:R-HSA-3196156 "PR:O75469 located_in GO:0005654"
xref: Reactome:R-HSA-3196164 "PR:O75469 located_in GO:0005654"
xref: DTO:00117497
xref: UniProtKB:O75469
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011397 ! nuclear receptor subfamily 1 group I member 2
relationship: has_gene_template HGNC:7968 ! NR1I2 (human)

[Term]
id: PR:Q9R1A7-1
name: nuclear receptor subfamily 1 group I member 2 isoform 1 (rat)
def: "A nuclear receptor subfamily 1 group I member 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rNR1I2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9R1A7-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038211 ! nuclear receptor subfamily 1 group I member 2 isoform 1

[Term]
id: PR:000038211
name: nuclear receptor subfamily 1 group I member 2 isoform 1
def: "A nuclear receptor subfamily 1 group I member 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54915-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "NR1I2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000011397 ! nuclear receptor subfamily 1 group I member 2

[Term]
id: PR:Q9R1A7
name: nuclear receptor subfamily 1 group I member 2 (rat)
def: "A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of rat." [OMA:Q9R1A7, PANTHER:PTHR24082:SF165, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pxr" RELATED Gene-based [UniProtKB:Q9R1A7]
synonym: "Nr1i2" RELATED Gene-based [UniProtKB:Q9R1A7]
synonym: "rNR1I2" EXACT PRO-short-label [PRO:DNx]
synonym: "pregnane X receptor (rat)" EXACT [UniProtKB:Q9R1A7]
synonym: "orphan nuclear receptor PXR (rat)" EXACT [UniProtKB:Q9R1A7]
xref: UniProtKB:Q9R1A7
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000011397 ! nuclear receptor subfamily 1 group I member 2
relationship: has_gene_template RGD:69057 ! Nr1i2 (rat)

[Term]
id: PR:O54915
name: nuclear receptor subfamily 1 group I member 2 (mouse)
def: "A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of mouse." [OMA:O54915, PRO:DNx]
comment: Category=organism-gene.
synonym: "Pxr" RELATED Gene-based [UniProtKB:O54915]
synonym: "Nr1i2" RELATED Gene-based [UniProtKB:O54915]
synonym: "mNR1I2" EXACT PRO-short-label [PRO:DNx]
synonym: "pregnane X receptor (mouse)" EXACT [UniProtKB:O54915]
synonym: "orphan nuclear receptor PXR (mouse)" EXACT [UniProtKB:O54915]
xref: UniProtKB:O54915
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011397 ! nuclear receptor subfamily 1 group I member 2
relationship: has_gene_template MGI:1337040 ! Nr1i2 (mouse)

[Term]
id: PR:000045606
name: nuclear receptor subfamily 1 group I member 2 phosphorylated 1 (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that has been phosphorylated at the position equivalent to Ser-350 of the amino acid sequence represented by UniProtKB:O75469-1. Example: UniProtKB:O75469-1, Ser-350, MOD:00046." [PMID:18784074, iPTMnet:O75469]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18784074). Status=unreviewed.
synonym: "hNR1I2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O75469-1, Ser-350, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000011397
name: nuclear receptor subfamily 1 group I member 2
def: "A protein that is a translation product of the human NR1I2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "PXR" RELATED Gene-based []
synonym: "SXR" EXACT []
synonym: "NR1I2" EXACT PRO-short-label [PRO:DNx]
synonym: "pregnane X receptor" EXACT []
synonym: "orphan nuclear receptor PXR" EXACT []
synonym: "orphan nuclear receptor PAR1" EXACT []
synonym: "steroid and xenobiotic receptor" EXACT []
xref: IUPHARobj:606
is_a: PR:000000001 ! protein

[Term]
id: PR:O75469-3
name: nuclear receptor subfamily 1 group I member 2 isoform h1C (human)
def: "A nuclear receptor subfamily 1 group I member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75469-3." [PRO:DNx, UniProtKB:O75469]
comment: Category=organism-sequence.
synonym: "hNR1I2/iso:h1C" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear receptor subfamily 1 group I member 2 isoform PRR1-C (human)" EXACT [UniProtKB:O75469]
xref: UniProtKB:O75469-3
is_a: PR:O75469 ! nuclear receptor subfamily 1 group I member 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens