[Term]
id: PR:Q13469-4
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform h4 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13469-4." [PRO:DNx, UniProtKB:Q13469]
comment: Category=organism-sequence.
synonym: "hNFATC2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13469-4
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13469
name: nuclear factor of activated T-cells, cytoplasmic 2 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13469]
comment: Category=organism-gene.
synonym: "NFAT1" RELATED Gene-based [UniProtKB:Q13469]
synonym: "NFATP" RELATED Gene-based [UniProtKB:Q13469]
synonym: "NFATC2" RELATED Gene-based [UniProtKB:Q13469]
synonym: "hNFATC2" EXACT PRO-short-label [PRO:DNx]
synonym: "NF-ATp (human)" EXACT [UniProtKB:Q13469]
synonym: "NFATc2 (human)" EXACT [UniProtKB:Q13469]
synonym: "NF-ATc2 (human)" EXACT [UniProtKB:Q13469]
synonym: "NFAT pre-existing subunit (human)" EXACT [UniProtKB:Q13469]
synonym: "T-cell transcription factor NFAT1 (human)" EXACT [UniProtKB:Q13469]
xref: Reactome:R-HSA-3791114 "PR:Q13469 located_in GO:0005654"
xref: UniProtKB:Q13469
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011164 ! nuclear factor of activated T-cells, cytoplasmic 2
relationship: has_gene_template HGNC:7776 ! NFATC2 (human)

[Term]
id: PR:Q13469-1
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform h1 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13469-1." [PRO:DNx, UniProtKB:Q13469]
comment: Category=organism-sequence.
synonym: "hNFATC2/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform C (human)" EXACT [UniProtKB:Q13469]
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform NFATc2_IB_IIL (human)" EXACT [UniProtKB:Q13469]
xref: UniProtKB:Q13469-1
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13469-2
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform h2 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13469-2." [PRO:DNx, UniProtKB:Q13469]
comment: Category=organism-sequence.
synonym: "hNFATC2/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform B (human)" EXACT [UniProtKB:Q13469]
xref: UniProtKB:Q13469-2
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13469-3
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform h3 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13469-3." [PRO:DNx, UniProtKB:Q13469]
comment: Category=organism-sequence.
synonym: "hNFATC2/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform NFATc2_IA_IIL (human)" EXACT [UniProtKB:Q13469]
xref: UniProtKB:Q13469-3
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q60591
name: nuclear factor of activated T-cells, cytoplasmic 2 (mouse)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 that is encoded in the genome of mouse." [OMA:Q60591, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nfat1" RELATED Gene-based [UniProtKB:Q60591]
synonym: "Nfatp" RELATED Gene-based [UniProtKB:Q60591]
synonym: "Nfatc2" RELATED Gene-based [UniProtKB:Q60591]
synonym: "mNFATC2" EXACT PRO-short-label [PRO:DNx]
synonym: "NF-ATp (mouse)" EXACT [UniProtKB:Q60591]
synonym: "NFATc2 (mouse)" EXACT [UniProtKB:Q60591]
synonym: "NF-ATc2 (mouse)" EXACT [UniProtKB:Q60591]
synonym: "NFAT pre-existing subunit (mouse)" EXACT [UniProtKB:Q60591]
synonym: "T-cell transcription factor NFAT1 (mouse)" EXACT [UniProtKB:Q60591]
xref: UniProtKB:Q60591
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011164 ! nuclear factor of activated T-cells, cytoplasmic 2
relationship: has_gene_template MGI:102463 ! Nfatc2 (mouse)

[Term]
id: PR:Q13469-5
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform h5 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13469-5." [PRO:DNx, UniProtKB:Q13469]
comment: Category=organism-sequence.
synonym: "hNFATC2/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13469-5
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q60591-2
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform 2 (mouse)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60591-2." [PMID:8668213, PRO:KRC, UniProtKB:Q60591]
comment: Category=organism-sequence. Note: PMID:8668213 shows isolation of cDNAs for isoforms A, B, and C (though UniProt record indicates that cDNA for isoform A is chimeric).
synonym: "mNFATC2/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "NFAT1-B (mouse)" EXACT []
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform B (mouse)" EXACT []
xref: UniProtKB:Q60591-2
is_a: PR:Q60591 ! nuclear factor of activated T-cells, cytoplasmic 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q60591-3
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform 3 (mouse)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60591-3." [PMID:8668213, PRO:KRC, UniProtKB:Q60591]
comment: Category=organism-sequence. Note: PMID:8668213 shows isolation of cDNAs for isoforms A, B, and C (though UniProt record indicates that cDNA for isoform A is chimeric).
synonym: "mNFATC2/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "NFAT1-C (mouse)" EXACT []
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform C (mouse)" EXACT []
xref: UniProtKB:Q60591-3
is_a: PR:Q60591 ! nuclear factor of activated T-cells, cytoplasmic 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q60591-1
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform 1 (mouse)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60591-1." [PMID:8235597, PMID:8668213, PRO:KRC, UniProtKB:Q60591-1]
comment: Category=organism-sequence. Note: PMID:8235597 identifies a partial cDNA. PMID:8668213 also identifies a cDNA for isoform A (but the sequence shown in then paper seems to be a chimeric DNA), as well as cDNAs for isoforms B and C.
synonym: "mNFATC2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q60591-1
is_a: PR:Q60591 ! nuclear factor of activated T-cells, cytoplasmic 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q60591-4
name: nuclear factor of activated T-cells, cytoplasmic 2 isoform 4 (mouse)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q60591-4." [PMID:11278367, PRO:KRC]
comment: Category=organism-sequence. Note: PMID:11278367 shows isolation of cDNA for isoform D, and expression of isoform D mRNA in brain, and showed presence of isoform D protein in brain by Western.
synonym: "mNFATC2/iso:4" EXACT PRO-short-label [PRO:DNx]
synonym: "NFAT1-D (mouse)" EXACT []
synonym: "nuclear factor of activated T-cells, cytoplasmic 2 isoform D (mouse)" EXACT []
xref: UniProtKB:Q60591-4
is_a: PR:Q60591 ! nuclear factor of activated T-cells, cytoplasmic 2 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000048590
name: nuclear factor of activated T-cells, cytoplasmic 2 phosphorylated 1 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that has been post-translationally modified to include phosphoserine at positions 171, 172, 174, 175, 177, 213, 217, 221, 243, 268, 274, 276, 280 and 326 of the amino acid sequence represented by UniProtKB:Q13469. UniProtKB:Q13469, Ser-171/Ser-172/Ser-174/Ser-175/Ser-177/Ser-213/Ser-217/Ser-221/Ser-243/Ser-268/Ser-274/Ser-276/Ser-280/Ser-326, MOD:00046." [PRO:DNx, Reactome:R-HSA-2025848]
comment: Category=organism-modification.
synonym: "hNFATC2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13469, Ser-171/Ser-172/Ser-174/Ser-175/Ser-177/Ser-213/Ser-217/Ser-221/Ser-243/Ser-268/Ser-274/Ser-276/Ser-280/Ser-326, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2025848 "PR:000048590 located_in GO:0005829"
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048591
name: nuclear factor of activated T-cells, cytoplasmic 2 phosphorylated 2 (human)
def: "A nuclear factor of activated T-cells, cytoplasmic 2 (human) that has been post-translationally modified to include phosphoserine at position 243 of the amino acid sequence represented by UniProtKB:Q13469. UniProtKB:Q13469, Ser-243, MOD:00046." [PRO:DNx, Reactome:R-HSA-2025894, Reactome:R-HSA-2685626]
comment: Category=organism-modification.
synonym: "hNFATC2/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13469, Ser-243, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2025894 "PR:000048591 located_in GO:0005654"
xref: Reactome:R-HSA-2685626 "PR:000048591 located_in GO:0005829"
is_a: PR:Q13469 ! nuclear factor of activated T-cells, cytoplasmic 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000011164
name: nuclear factor of activated T-cells, cytoplasmic 2
def: "A protein that is a translation product of the human NFATC2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NFAT1" RELATED Gene-based []
synonym: "NFATP" RELATED Gene-based []
synonym: "NF-ATp" EXACT []
synonym: "NFATC2" EXACT PRO-short-label [PRO:DNx]
synonym: "NFATc2" EXACT []
synonym: "NF-ATc2" EXACT []
synonym: "NFAT pre-existing subunit" EXACT []
synonym: "T-cell transcription factor NFAT1" EXACT []
is_a: PR:000000001 ! protein