[Term]
id: PR:000011145
name: sialidase-1
def: "A vertebrate-like neuraminidase that is a translation product of the human NEU1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Neu" RELATED Gene-based []
synonym: "NANH" RELATED Gene-based []
synonym: "NEU1" EXACT PRO-short-label [PRO:DNx]
synonym: "G9 sialidase" EXACT []
synonym: "lysosomal sialidase" EXACT []
synonym: "acetylneuraminyl hydrolase" EXACT []
synonym: "N-acetyl-alpha-neuraminidase 1" EXACT []
is_a: PR:000022007 ! vertebrate-like neuraminidase

[Term]
id: PR:Q99PW3
name: sialidase-1 (rat)
def: "A sialidase-1 that is encoded in the genome of rat." [PANTHER:PTHR10628:SF9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Neu1" RELATED Gene-based [UniProtKB:Q99PW3]
synonym: "rNEU1" EXACT PRO-short-label [PRO:DNx]
synonym: "lysosomal sialidase (rat)" EXACT [UniProtKB:Q99PW3]
synonym: "N-acetyl-alpha-neuraminidase 1 (rat)" EXACT [UniProtKB:Q99PW3]
xref: UniProtKB:Q99PW3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000011145 ! sialidase-1
relationship: has_gene_template RGD:3163 ! Neu1 (rat)

[Term]
id: PR:Q99519
name: sialidase-1 (human)
def: "A sialidase-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q99519]
comment: Category=organism-gene.
synonym: "NANH" RELATED Gene-based [UniProtKB:Q99519]
synonym: "NEU1" RELATED Gene-based [UniProtKB:Q99519]
synonym: "hNEU1" EXACT PRO-short-label [PRO:DNx]
synonym: "G9 sialidase (human)" EXACT [UniProtKB:Q99519]
synonym: "lysosomal sialidase (human)" EXACT [UniProtKB:Q99519]
synonym: "acetylneuraminyl hydrolase (human)" EXACT [UniProtKB:Q99519]
synonym: "N-acetyl-alpha-neuraminidase 1 (human)" EXACT [UniProtKB:Q99519]
xref: UniProtKB:Q99519
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000011145 ! sialidase-1
relationship: has_gene_template HGNC:7758 ! NEU1 (human)

[Term]
id: PR:000048582
name: sialidase-1, signal peptide removed form (human)
def: "A sialidase-1 (human) that has had the signal peptide removed. UniProtKB:Q99519, 48-415." [PRO:DNx, Reactome:R-HSA-1605788]
comment: Category=organism-modification.
synonym: "hNEU1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000012026" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q99519, 48-415" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1605788 "PR:000048582 located_in GO:0043202"
xref: Reactome:R-HSA-6806148 "PR:000048582 located_in GO:0035580"
xref: Reactome:R-HSA-6806158 "PR:000048582 located_in GO:0005576"
intersection_of: PR:Q99519 ! sialidase-1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O35657
name: sialidase-1 (mouse)
def: "A sialidase-1 that is encoded in the genome of mouse." [OMA:O35657, PRO:DNx]
comment: Category=organism-gene.
synonym: "Neu" RELATED Gene-based [UniProtKB:O35657]
synonym: "Neu1" RELATED Gene-based [UniProtKB:O35657]
synonym: "mNEU1" EXACT PRO-short-label [PRO:DNx]
synonym: "G9 sialidase (mouse)" EXACT [UniProtKB:O35657]
synonym: "lysosomal sialidase (mouse)" EXACT [UniProtKB:O35657]
synonym: "N-acetyl-alpha-neuraminidase 1 (mouse)" EXACT [UniProtKB:O35657]
xref: UniProtKB:O35657
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000011145 ! sialidase-1
relationship: has_gene_template MGI:97305 ! Neu1 (mouse)

[Term]
id: PR:000020732
name: sialidase-1, signal peptide removed form
def: "A sialidase-1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "NEU1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000011145 ! sialidase-1
intersection_of: lacks_part SO:0000418 ! signal_peptide